Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue CA A 501 |
| Chain | Residue |
| A | GLU63 |
| A | ASP374 |
| A | SER376 |
| A | VAL379 |
| A | EDO509 |
| A | HOH684 |
| A | HOH953 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue CA A 502 |
| Chain | Residue |
| A | HOH948 |
| A | HOH949 |
| A | HOH950 |
| A | HOH951 |
| A | HOH952 |
| A | HOH678 |
| A | HOH680 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue PEG A 503 |
| Chain | Residue |
| A | ARG301 |
| A | ASN329 |
| A | PHE355 |
| A | THR356 |
| A | HOH921 |
| A | HOH955 |
| A | HOH961 |
| B | TYR390 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | TYR106 |
| A | ARG107 |
| A | ASN108 |
| A | LEU130 |
| A | GLU132 |
| A | HOH640 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | TYR100 |
| A | ASP140 |
| A | TRP350 |
| A | ARG370 |
| A | HOH958 |
| B | ILE409 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 506 |
| Chain | Residue |
| A | GLU146 |
| A | LYS175 |
| A | TYR177 |
| A | EDO512 |
| A | HOH606 |
| A | HOH628 |
| A | HOH777 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 507 |
| Chain | Residue |
| A | ASN53 |
| A | ASN319 |
| A | ILE320 |
| A | HOH795 |
| A | HOH870 |
| A | HOH960 |
| A | HOH965 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 508 |
| Chain | Residue |
| A | LYS238 |
| A | LYS343 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 509 |
| Chain | Residue |
| A | GLU60 |
| A | ASN61 |
| A | ASN62 |
| A | GLU63 |
| A | ASP374 |
| A | LYS385 |
| A | CA501 |
| A | HOH828 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 510 |
| Chain | Residue |
| A | ARG408 |
| A | ILE409 |
| A | HOH1005 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 511 |
| Chain | Residue |
| A | THR342 |
| A | LYS343 |
| A | TYR344 |
| A | HOH872 |
| A | HOH977 |
| site_id | AD3 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 512 |
| Chain | Residue |
| A | TRP134 |
| A | GLY148 |
| A | TYR177 |
| A | PRO267 |
| A | EDO506 |
| A | HOH604 |
| A | HOH608 |
| A | HOH636 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 513 |
| Chain | Residue |
| A | TRP172 |
| A | LYS173 |
| A | HOH726 |
| A | HOH797 |
| A | HOH966 |
| A | HOH1003 |
| site_id | AD5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 514 |
| Chain | Residue |
| A | PHE76 |
| A | ASP77 |
| A | TYR78 |
| A | GLY80 |
| A | HIS81 |
| A | HOH770 |
| A | HOH994 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 515 |
| Chain | Residue |
| A | ASN97 |
| A | LYS99 |
| A | TYR101 |
| A | ASP205 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 516 |
| Chain | Residue |
| A | LYS36 |
| A | TYR51 |
| A | MET55 |
| A | HOH717 |
| A | HOH967 |
| A | HOH1016 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 517 |
| Chain | Residue |
| A | LYS139 |
| A | GLU213 |
| A | HOH601 |
| A | HOH603 |
| A | HOH873 |
| A | THR137 |
| A | SER138 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 518 |
| Chain | Residue |
| A | LYS156 |
| A | PRO157 |
| A | TRP161 |
| A | HOH886 |
| B | ASP252 |
| site_id | AE1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 519 |
| Chain | Residue |
| A | GLU325 |
| A | PHE326 |
| A | HOH1030 |
| B | GLU325 |
| B | PHE326 |
| site_id | AE2 |
| Number of Residues | 10 |
| Details | binding site for residue EDO A 520 |
| Chain | Residue |
| A | TYR70 |
| A | PHE326 |
| A | MET327 |
| A | PRO328 |
| A | ASN329 |
| A | PHE355 |
| A | HOH689 |
| A | HOH850 |
| A | HOH921 |
| B | TYR396 |
| site_id | AE3 |
| Number of Residues | 11 |
| Details | binding site for residue 3DY A 521 |
| Chain | Residue |
| A | ARG88 |
| A | ASP89 |
| A | TRP128 |
| A | THR166 |
| A | GLN181 |
| A | ASP192 |
| A | ASP231 |
| A | LYS246 |
| A | GLU285 |
| A | HIS354 |
| A | HOH1004 |
| site_id | AE4 |
| Number of Residues | 7 |
| Details | binding site for residue CA B 501 |
| Chain | Residue |
| B | HOH648 |
| B | HOH660 |
| B | HOH794 |
| B | HOH795 |
| B | HOH796 |
| B | HOH797 |
| B | HOH798 |
| site_id | AE5 |
| Number of Residues | 7 |
| Details | binding site for residue CA B 502 |
| Chain | Residue |
| B | GLU63 |
| B | ASP374 |
| B | SER376 |
| B | VAL379 |
| B | HOH609 |
| B | HOH674 |
| B | HOH691 |
| site_id | AE6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 503 |
| Chain | Residue |
| B | ASN53 |
| B | TYR54 |
| B | MET55 |
| B | ASN319 |
| B | ILE320 |
| B | ALA321 |
| B | HOH809 |
| site_id | AE7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 504 |
| Chain | Residue |
| A | LYS74 |
| A | PHE142 |
| A | HOH739 |
| A | HOH848 |
| B | ARG406 |
| site_id | AE8 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 505 |
| Chain | Residue |
| B | THR166 |
| B | GLN181 |
| B | HOH684 |
| site_id | AE9 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 506 |
| Chain | Residue |
| B | SER274 |
| B | PRO275 |
| site_id | AF1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 507 |
| Chain | Residue |
| B | LYS246 |
| B | HIS284 |
| B | GLU285 |
| B | HOH764 |
| B | HOH765 |
