Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 501 |
| Chain | Residue |
| A | GLU78 |
| A | ASP397 |
| A | SER399 |
| A | VAL402 |
| A | HOH729 |
| A | HOH737 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue CA A 502 |
| Chain | Residue |
| A | HOH636 |
| A | HOH637 |
| A | HOH638 |
| A | HOH671 |
| A | HOH633 |
| A | HOH634 |
| A | HOH635 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue PEG A 503 |
| Chain | Residue |
| A | ARG103 |
| A | ASP104 |
| A | THR184 |
| A | GLN199 |
| A | LYS264 |
| A | GLU307 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue PEG A 504 |
| Chain | Residue |
| A | ALA137 |
| A | ASP139 |
| A | LYS174 |
| A | TRP179 |
| C | LYS239 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | ASP249 |
| A | TYR263 |
| A | THR308 |
| A | TYR310 |
| A | HOH671 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 506 |
| Chain | Residue |
| A | ALA286 |
| A | ASP287 |
| A | ASP288 |
| A | GLY291 |
| A | PRO292 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 501 |
| Chain | Residue |
| B | GLU78 |
| B | ASP397 |
| B | SER399 |
| B | VAL402 |
| B | HOH671 |
| B | HOH675 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue CA B 502 |
| Chain | Residue |
| B | HOH634 |
| B | HOH635 |
| B | HOH636 |
| B | HOH638 |
| B | HOH639 |
| B | HOH640 |
| B | HOH641 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue ACY B 503 |
| Chain | Residue |
| A | HIS414 |
| B | THR351 |
| B | PHE377 |
| B | THR378 |
| B | ASN379 |
| site_id | AD1 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 504 |
| Chain | Residue |
| B | ASP249 |
| B | GLN251 |
| B | TYR262 |
| B | TYR263 |
| B | THR308 |
| B | TYR310 |
| B | HOH639 |
| B | HOH733 |
| site_id | AD2 |
| Number of Residues | 1 |
| Details | binding site for residue EDO B 505 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 506 |
| Chain | Residue |
| B | GLY113 |
| B | GLU157 |
| B | HOH719 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue CA C 501 |
| Chain | Residue |
| C | GLU78 |
| C | ASP397 |
| C | SER399 |
| C | VAL402 |
| C | HOH683 |
| C | HOH761 |
| C | HOH762 |
| site_id | AD5 |
| Number of Residues | 7 |
| Details | binding site for residue CA C 502 |
| Chain | Residue |
| C | HOH630 |
| C | HOH631 |
| C | HOH632 |
| C | HOH633 |
| C | HOH635 |
| C | HOH636 |
| C | HOH637 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue EDO C 503 |
| Chain | Residue |
| C | ASP123 |
| C | HOH752 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 504 |
| Chain | Residue |
| C | GLY257 |
| C | LYS258 |
| C | ASP287 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO C 505 |
| Chain | Residue |
| C | ASP249 |
| C | GLN251 |
| C | TYR262 |
| C | HIS281 |
| C | THR308 |
| C | HOH635 |
| C | HOH687 |
| site_id | AD9 |
| Number of Residues | 7 |
| Details | binding site for residue CA D 501 |
| Chain | Residue |
| D | GLU78 |
| D | ASP397 |
| D | SER399 |
| D | VAL402 |
| D | HOH741 |
| D | HOH752 |
| D | HOH753 |
| site_id | AE1 |
| Number of Residues | 7 |
| Details | binding site for residue CA D 502 |
| Chain | Residue |
| D | HOH631 |
| D | HOH632 |
| D | HOH633 |
| D | HOH634 |
| D | HOH635 |
| D | HOH628 |
| D | HOH630 |
| site_id | AE2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO D 503 |
| Chain | Residue |
| C | GLU417 |
| C | PHE420 |
| D | ARG87 |
| site_id | AE3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO D 504 |
| Chain | Residue |
| D | TYR153 |
| D | GLU165 |
| D | VAL167 |
| site_id | AE4 |
| Number of Residues | 2 |
| Details | binding site for residue EDO D 505 |
| Chain | Residue |
| D | ASP123 |
| D | HOH746 |
