4U1T

The crystal structure of holo CalE6, a methionine gamma lyase from Micromonospora echinospora

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0005737	cellular_component	cytoplasm
A	0016846	molecular_function	carbon-sulfur lyase activity
A	0018826	molecular_function	methionine gamma-lyase activity
A	0019346	biological_process	transsulfuration
A	0030170	molecular_function	pyridoxal phosphate binding
A	0047982	molecular_function	homocysteine desulfhydrase activity
B	0003824	molecular_function	catalytic activity
B	0005737	cellular_component	cytoplasm
B	0016846	molecular_function	carbon-sulfur lyase activity
B	0018826	molecular_function	methionine gamma-lyase activity
B	0019346	biological_process	transsulfuration
B	0030170	molecular_function	pyridoxal phosphate binding
B	0047982	molecular_function	homocysteine desulfhydrase activity
C	0003824	molecular_function	catalytic activity
C	0005737	cellular_component	cytoplasm
C	0016846	molecular_function	carbon-sulfur lyase activity
C	0018826	molecular_function	methionine gamma-lyase activity
C	0019346	biological_process	transsulfuration
C	0030170	molecular_function	pyridoxal phosphate binding
C	0047982	molecular_function	homocysteine desulfhydrase activity
D	0003824	molecular_function	catalytic activity
D	0005737	cellular_component	cytoplasm
D	0016846	molecular_function	carbon-sulfur lyase activity
D	0018826	molecular_function	methionine gamma-lyase activity
D	0019346	biological_process	transsulfuration
D	0030170	molecular_function	pyridoxal phosphate binding
D	0047982	molecular_function	homocysteine desulfhydrase activity
E	0003824	molecular_function	catalytic activity
E	0005737	cellular_component	cytoplasm
E	0016846	molecular_function	carbon-sulfur lyase activity
E	0018826	molecular_function	methionine gamma-lyase activity
E	0019346	biological_process	transsulfuration
E	0030170	molecular_function	pyridoxal phosphate binding
E	0047982	molecular_function	homocysteine desulfhydrase activity
F	0003824	molecular_function	catalytic activity
F	0005737	cellular_component	cytoplasm
F	0016846	molecular_function	carbon-sulfur lyase activity
F	0018826	molecular_function	methionine gamma-lyase activity
F	0019346	biological_process	transsulfuration
F	0030170	molecular_function	pyridoxal phosphate binding
F	0047982	molecular_function	homocysteine desulfhydrase activity
G	0003824	molecular_function	catalytic activity
G	0005737	cellular_component	cytoplasm
G	0016846	molecular_function	carbon-sulfur lyase activity
G	0018826	molecular_function	methionine gamma-lyase activity
G	0019346	biological_process	transsulfuration
G	0030170	molecular_function	pyridoxal phosphate binding
G	0047982	molecular_function	homocysteine desulfhydrase activity
H	0003824	molecular_function	catalytic activity
H	0005737	cellular_component	cytoplasm
H	0016846	molecular_function	carbon-sulfur lyase activity
H	0018826	molecular_function	methionine gamma-lyase activity
H	0019346	biological_process	transsulfuration
H	0030170	molecular_function	pyridoxal phosphate binding
H	0047982	molecular_function	homocysteine desulfhydrase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue SO4 A 401

Chain	Residue
A	TYR100
A	HOH787
A	LLP197
A	VAL322
A	SER323
A	THR338
A	ARG358
A	HOH541
A	HOH664
A	HOH754

---

site_id	AC2
Number of Residues	9
Details	binding site for residue SO4 B 401

Chain	Residue
B	TYR100
B	ASN147
B	LLP197
B	SER323
B	THR338
B	ARG358
B	HOH598
B	HOH676
B	HOH758

---

site_id	AC3
Number of Residues	6
Details	binding site for residue SO4 C 401

Chain	Residue
C	TYR100
C	LLP197
C	SER323
C	ARG358
C	HOH673
C	HOH686

---

site_id	AC4
Number of Residues	7
Details	binding site for residue SO4 D 401

Chain	Residue
D	TYR100
D	LLP197
D	SER323
D	LEU324
D	ARG358
D	HOH699
D	HOH703

---

site_id	AC5
Number of Residues	11
Details	binding site for residue SO4 E 401

Chain	Residue
E	TYR100
E	ASN147
E	LLP197
E	VAL322
E	SER323
E	LEU324
E	ARG358
E	HOH678
E	HOH680
E	HOH724
E	HOH759

---

site_id	AC6
Number of Residues	12
Details	binding site for residue SO4 F 401

Chain	Residue
F	TYR100
F	ASN147
F	LLP197
F	VAL322
F	SER323
F	LEU324
F	THR338
F	ARG358
F	HOH635
F	HOH673
F	HOH687
F	HOH759

---

site_id	AC7
Number of Residues	7
Details	binding site for residue SO4 G 401

Chain	Residue
G	TYR100
G	LLP197
G	VAL322
G	SER323
G	ARG358
G	HOH597
G	HOH793

---

site_id	AC8
Number of Residues	8
Details	binding site for residue SO4 H 401

Chain	Residue
H	TYR100
H	LLP197
H	VAL322
H	SER323
H	THR338
H	ARG358
H	HOH645
H	HOH769

---

Functional Information from PROSITE/UniProt

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. FSSGQAAAATLLSLV

Chain	Residue	Details
A	PHE73-VAL87

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