Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004252 | molecular_function | serine-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 19 |
Details | binding site for residue 39D A 301 |
Chain | Residue |
A | HIS40 |
A | ASP194 |
A | SER195 |
A | THR213 |
A | GLY218 |
A | EDO303 |
A | HOH484 |
A | HOH539 |
A | HOH618 |
A | HOH621 |
A | HOH622 |
A | HIS57 |
A | TYR143 |
A | ILE151 |
A | ASP189 |
A | ALA190 |
A | CYS191 |
A | LYS192 |
A | GLY193 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue SO4 A 302 |
Chain | Residue |
A | ARG170 |
A | ARG170 |
A | ARG184 |
A | ARG184 |
site_id | AC3 |
Number of Residues | 6 |
Details | binding site for residue EDO A 303 |
Chain | Residue |
A | GLY216 |
A | GLY218 |
A | 39D301 |
A | HOH448 |
A | HOH504 |
A | HOH622 |
site_id | AC4 |
Number of Residues | 7 |
Details | binding site for residue EDO A 304 |
Chain | Residue |
A | ASN49 |
A | THR111 |
A | VAL112 |
A | GLY113 |
A | TYR114 |
A | HOH633 |
A | HOH638 |
site_id | AC5 |
Number of Residues | 8 |
Details | binding site for residue EDO A 305 |
Chain | Residue |
A | ARG24 |
A | SER99 |
A | GLY173 |
A | HIS174 |
A | LYS175 |
A | HOH414 |
A | HOH429 |
A | HOH458 |
site_id | AC6 |
Number of Residues | 9 |
Details | binding site for residue EDO A 306 |
Chain | Residue |
A | ARG24 |
A | GLY25 |
A | GLU26 |
A | TRP27 |
A | PRO28 |
A | ILE70 |
A | LEU71 |
A | HOH426 |
A | HOH625 |
site_id | AC7 |
Number of Residues | 2 |
Details | binding site for residue EDO A 307 |
Chain | Residue |
A | LYS175 |
A | HIS178 |
site_id | AC8 |
Number of Residues | 3 |
Details | binding site for residue EDO A 308 |
Chain | Residue |
A | HIS34 |
A | ILE76 |
A | HOH542 |
site_id | AC9 |
Number of Residues | 7 |
Details | binding site for residue EDO A 309 |
Chain | Residue |
A | GLU167 |
A | ARG170 |
A | TYR184 |
A | ARG184 |
A | GLU223 |
A | PRO225 |
A | HOH507 |
site_id | AD1 |
Number of Residues | 4 |
Details | binding site for residue EDO A 310 |
Chain | Residue |
A | GLU26 |
A | TRP137 |
A | LYS157 |
A | HOH623 |
Functional Information from PROSITE/UniProt
site_id | PS00134 |
Number of Residues | 6 |
Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
Chain | Residue | Details |
A | LEU53-CYS58 | |
site_id | PS00135 |
Number of Residues | 12 |
Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DAckGDSGGPLS |
Chain | Residue | Details |
A | ASP189-SER200 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 3 |
Details | ACT_SITE: Charge relay system |
Chain | Residue | Details |
A | HIS57 | |
A | ASP102 | |
A | SER195 | |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | BINDING: |
Chain | Residue | Details |
A | LYS169 | |
Chain | Residue | Details |
A | ASN72 | |
Chain | Residue | Details |
A | GLY113 | |