4TUG

Crystal structure of MjMre11-DNA2 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000403	molecular_function	Y-form DNA binding
A	0003677	molecular_function	DNA binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004527	molecular_function	exonuclease activity
A	0004529	molecular_function	DNA exonuclease activity
A	0006281	biological_process	DNA repair
A	0006302	biological_process	double-strand break repair
A	0006974	biological_process	DNA damage response
A	0008408	molecular_function	3'-5' exonuclease activity
A	0016787	molecular_function	hydrolase activity
A	0030145	molecular_function	manganese ion binding
A	0042802	molecular_function	identical protein binding
A	0045027	molecular_function	DNA end binding
A	0046872	molecular_function	metal ion binding
B	0000403	molecular_function	Y-form DNA binding
B	0003677	molecular_function	DNA binding
B	0004518	molecular_function	nuclease activity
B	0004519	molecular_function	endonuclease activity
B	0004527	molecular_function	exonuclease activity
B	0004529	molecular_function	DNA exonuclease activity
B	0006281	biological_process	DNA repair
B	0006302	biological_process	double-strand break repair
B	0006974	biological_process	DNA damage response
B	0008408	molecular_function	3'-5' exonuclease activity
B	0016787	molecular_function	hydrolase activity
B	0030145	molecular_function	manganese ion binding
B	0042802	molecular_function	identical protein binding
B	0045027	molecular_function	DNA end binding
B	0046872	molecular_function	metal ion binding
C	0000403	molecular_function	Y-form DNA binding
C	0003677	molecular_function	DNA binding
C	0004518	molecular_function	nuclease activity
C	0004519	molecular_function	endonuclease activity
C	0004527	molecular_function	exonuclease activity
C	0004529	molecular_function	DNA exonuclease activity
C	0006281	biological_process	DNA repair
C	0006302	biological_process	double-strand break repair
C	0006974	biological_process	DNA damage response
C	0008408	molecular_function	3'-5' exonuclease activity
C	0016787	molecular_function	hydrolase activity
C	0030145	molecular_function	manganese ion binding
C	0042802	molecular_function	identical protein binding
C	0045027	molecular_function	DNA end binding
C	0046872	molecular_function	metal ion binding
D	0000403	molecular_function	Y-form DNA binding
D	0003677	molecular_function	DNA binding
D	0004518	molecular_function	nuclease activity
D	0004519	molecular_function	endonuclease activity
D	0004527	molecular_function	exonuclease activity
D	0004529	molecular_function	DNA exonuclease activity
D	0006281	biological_process	DNA repair
D	0006302	biological_process	double-strand break repair
D	0006974	biological_process	DNA damage response
D	0008408	molecular_function	3'-5' exonuclease activity
D	0016787	molecular_function	hydrolase activity
D	0030145	molecular_function	manganese ion binding
D	0042802	molecular_function	identical protein binding
D	0045027	molecular_function	DNA end binding
D	0046872	molecular_function	metal ion binding
E	0000403	molecular_function	Y-form DNA binding
E	0003677	molecular_function	DNA binding
E	0004518	molecular_function	nuclease activity
E	0004519	molecular_function	endonuclease activity
E	0004527	molecular_function	exonuclease activity
E	0004529	molecular_function	DNA exonuclease activity
E	0006281	biological_process	DNA repair
E	0006302	biological_process	double-strand break repair
E	0006974	biological_process	DNA damage response
E	0008408	molecular_function	3'-5' exonuclease activity
E	0016787	molecular_function	hydrolase activity
E	0030145	molecular_function	manganese ion binding
E	0042802	molecular_function	identical protein binding
E	0045027	molecular_function	DNA end binding
E	0046872	molecular_function	metal ion binding
F	0000403	molecular_function	Y-form DNA binding
F	0003677	molecular_function	DNA binding
F	0004518	molecular_function	nuclease activity
F	0004519	molecular_function	endonuclease activity
F	0004527	molecular_function	exonuclease activity
F	0004529	molecular_function	DNA exonuclease activity
F	0006281	biological_process	DNA repair
F	0006302	biological_process	double-strand break repair
F	0006974	biological_process	DNA damage response
F	0008408	molecular_function	3'-5' exonuclease activity
F	0016787	molecular_function	hydrolase activity
F	0030145	molecular_function	manganese ion binding
F	0042802	molecular_function	identical protein binding
F	0045027	molecular_function	DNA end binding
F	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue MG C 401

Chain	Residue
C	ASP49
C	ASN84
C	HIS158
C	HIS186
C	MG402

---

site_id	AC2
Number of Residues	5
Details	binding site for residue MG C 402

Chain	Residue
C	MG401
C	ASP8
C	HIS10
C	ASP49
C	HIS188

---

site_id	AC3
Number of Residues	5
Details	binding site for residue MG A 401

Chain	Residue
A	ASP49
A	ASN84
A	HIS158
A	HIS186
A	MG402

---

site_id	AC4
Number of Residues	5
Details	binding site for residue MG A 402

Chain	Residue
A	ASP8
A	HIS10
A	ASP49
A	HIS188
A	MG401

---

site_id	AC5
Number of Residues	5
Details	binding site for residue MG B 401

Chain	Residue
B	ASP49
B	ASN84
B	HIS158
B	HIS186
B	MG402

---

site_id	AC6
Number of Residues	5
Details	binding site for residue MG B 402

Chain	Residue
B	ASP8
B	HIS10
B	ASP49
B	HIS188
B	MG401

---

site_id	AC7
Number of Residues	6
Details	binding site for residue MG D 401

Chain	Residue
D	ASP49
D	ASN84
D	HIS158
D	HIS186
D	MG402
D	HOH501

---

site_id	AC8
Number of Residues	6
Details	binding site for residue MG D 402

Chain	Residue
D	ASP8
D	HIS10
D	ASP49
D	HIS188
D	MG401
D	HOH501

---

site_id	AC9
Number of Residues	5
Details	binding site for residue MG E 401

Chain	Residue
E	ASP49
E	ASN84
E	HIS158
E	HIS186
E	MG402

---

site_id	AD1
Number of Residues	6
Details	binding site for residue MG E 402

Chain	Residue
E	ASP8
E	HIS10
E	ASP49
E	HIS188
E	MG401
E	HOH503

---

site_id	AD2
Number of Residues	5
Details	binding site for residue MG F 401

Chain	Residue
F	ASP49
F	ASN84
F	HIS158
F	HIS186
F	MG402

---

site_id	AD3
Number of Residues	7
Details	binding site for residue MG F 402

Chain	Residue
F	ASP8
F	HIS10
F	ASP49
F	HIS186
F	HIS188
F	MG401
F	HOH501

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_02044","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	42
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_02044","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---