Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004455 | molecular_function | ketol-acid reductoisomerase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| A | 0009097 | biological_process | isoleucine biosynthetic process |
| A | 0009099 | biological_process | L-valine biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue MG A 401 |
| Chain | Residue |
| A | ARG247 |
| A | TYR248 |
| A | ILE250 |
| A | ASP252 |
| A | GLN255 |
| A | HOH519 |
| A | HOH526 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 402 |
| Chain | Residue |
| A | GLU226 |
| A | TLA404 |
| A | HOH502 |
| A | ASP190 |
| A | GLU194 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 403 |
| Chain | Residue |
| A | ASP190 |
| A | GLU194 |
| A | TLA404 |
| A | HOH512 |
| A | HOH523 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | binding site for residue TLA A 404 |
| Chain | Residue |
| A | PRO132 |
| A | ASP190 |
| A | GLU194 |
| A | LEU198 |
| A | GLU230 |
| A | ILE250 |
| A | SER251 |
| A | ALA254 |
| A | MG402 |
| A | MG403 |
| A | NDP405 |
| A | HOH512 |
| A | HOH515 |
| A | HOH523 |
| site_id | AC5 |
| Number of Residues | 25 |
| Details | binding site for residue NDP A 405 |
| Chain | Residue |
| A | TYR25 |
| A | GLY26 |
| A | SER27 |
| A | GLN28 |
| A | ARG48 |
| A | SER52 |
| A | LEU79 |
| A | LEU80 |
| A | PRO81 |
| A | ASP82 |
| A | GLN85 |
| A | VAL88 |
| A | ALA106 |
| A | HIS107 |
| A | GLY131 |
| A | PRO132 |
| A | GLY133 |
| A | SER249 |
| A | ILE250 |
| A | SER251 |
| A | TLA404 |
| A | HOH513 |
| A | HOH528 |
| A | HOH536 |
| A | HOH541 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 179 |
| Details | Domain: {"description":"KARI N-terminal Rossmann","evidences":[{"source":"PROSITE-ProRule","id":"PRU01197","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 145 |
| Details | Domain: {"description":"KARI C-terminal knotted","evidences":[{"source":"PROSITE-ProRule","id":"PRU01198","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00435","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 11 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00435","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"25849365","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00435","evidenceCode":"ECO:0000255"}]} |
