4TQS

Ternary complex of Y-family DNA polymerase Dpo4 with (5'S)-8,5'-Cyclo-2'-deoxyguanosine and dCTP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0003677	molecular_function	DNA binding
A	0003684	molecular_function	damaged DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0005737	cellular_component	cytoplasm
A	0006260	biological_process	DNA replication
A	0006261	biological_process	DNA-templated DNA replication
A	0006281	biological_process	DNA repair
A	0006974	biological_process	DNA damage response
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0034061	molecular_function	DNA polymerase activity
A	0042276	biological_process	error-prone translesion synthesis
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0003677	molecular_function	DNA binding
B	0003684	molecular_function	damaged DNA binding
B	0003887	molecular_function	DNA-directed DNA polymerase activity
B	0005737	cellular_component	cytoplasm
B	0006260	biological_process	DNA replication
B	0006261	biological_process	DNA-templated DNA replication
B	0006281	biological_process	DNA repair
B	0006974	biological_process	DNA damage response
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0034061	molecular_function	DNA polymerase activity
B	0042276	biological_process	error-prone translesion synthesis
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	24
Details	binding site for residue DCP A 401

Chain	Residue
A	ASP7
A	ASP105
A	MG402
A	MG403
A	HOH602
A	HOH605
A	HOH613
A	HOH617
A	HOH619
A	HOH624
A	HOH696
A	PHE8
A	HOH722
P	DT12
P	DOC101
T	DG6
T	DA7
A	TYR10
A	PHE11
A	ALA44
A	THR45
A	TYR48
A	ARG51
A	GLY58

---

site_id	AC2
Number of Residues	5
Details	binding site for residue MG A 402

Chain	Residue
A	ASP7
A	PHE8
A	ASP105
A	DCP401
A	MG403

---

site_id	AC3
Number of Residues	7
Details	binding site for residue MG A 403

Chain	Residue
A	ASP7
A	ASP105
A	GLU106
A	DCP401
A	MG402
P	DOC101
P	HOH211

---

site_id	AC4
Number of Residues	24
Details	binding site for residue DCP B 401

Chain	Residue
B	ASP7
B	PHE8
B	ASP9
B	TYR10
B	PHE11
B	TYR12
B	ALA44
B	THR45
B	TYR48
B	ARG51
B	ALA57
B	GLY58
B	ASP105
B	LYS159
B	MG402
B	MG403
B	HOH507
B	HOH514
B	HOH580
B	HOH621
C	DT12
C	DOC101
D	DG6
D	DA7

---

site_id	AC5
Number of Residues	7
Details	binding site for residue MG B 402

Chain	Residue
B	ASP7
B	ASP105
B	GLU106
B	DCP401
B	MG403
C	DOC101
C	HOH207

---

site_id	AC6
Number of Residues	5
Details	binding site for residue MG B 403

Chain	Residue
B	ASP7
B	PHE8
B	ASP105
B	DCP401
B	MG402

---

site_id	AC7
Number of Residues	13
Details	binding site for residue DOC C 101

Chain	Residue
B	ALA102
B	ASP105
B	GLU106
B	LYS152
B	DCP401
B	MG402
B	HOH518
C	DT11
C	DT12
C	HOH203
C	HOH207
C	HOH210
D	DC11

---

site_id	AC8
Number of Residues	19
Details	binding site for Di-nucleotide DOC P 101 and DT P 12

Chain	Residue
T	DA7
T	DA8
T	DT9
T	DC10
T	HOH112
A	ALA102
A	ASP105
A	GLU106
A	LYS152
A	GLY185
A	DCP401
A	MG403
P	DA10
P	DT11
P	HOH202
P	HOH205
P	HOH207
P	HOH210
P	HOH211

---

site_id	AC9
Number of Residues	11
Details	binding site for Di-nucleotide 2LF T 5 and DG T 6

Chain	Residue
A	SER34
A	GLY41
A	ALA42
A	GLY58
A	PRO60
A	DCP401
A	HOH646
A	HOH691
T	DA7
T	HOH104
T	HOH105

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	368
Details	Domain: {"description":"UmuC"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Site: {"description":"Substrate discrimination"}

Chain

Residue

Details

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