4TQE

Structure of tau peptide in complex with Tau5 antibody Fab fragment

Functional Information from GO Data

Chain	GOid	namespace	contents
L	0002250	biological_process	adaptive immune response
L	0002376	biological_process	immune system process
L	0005576	cellular_component	extracellular region
L	0005886	cellular_component	plasma membrane
L	0019814	cellular_component	immunoglobulin complex
L	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue SO4 L 301

Chain	Residue
H	SER120
H	SER121
H	NA302
L	SER158
L	GLU159
L	NA305
L	HOH417

---

site_id	AC2
Number of Residues	5
Details	binding site for residue SO4 L 302

Chain	Residue
L	LYS112
L	HOH416
L	HOH441
L	SER28
L	VAL30

---

site_id	AC3
Number of Residues	3
Details	binding site for residue SO4 L 303

Chain	Residue
L	ARG113
L	ASP175
L	HOH547

---

site_id	AC4
Number of Residues	3
Details	binding site for residue SO4 L 304

Chain	Residue
L	ASN166
L	TRP168
L	NA307

---

site_id	AC5
Number of Residues	3
Details	binding site for residue NA L 305

Chain	Residue
H	VAL119
L	SER158
L	SO4301

---

site_id	AC6
Number of Residues	4
Details	binding site for residue NA L 306

Chain	Residue
L	SER14
L	ASP17
L	LYS112
L	HOH438

---

site_id	AC7
Number of Residues	2
Details	binding site for residue NA L 307

Chain	Residue
L	ASN166
L	SO4304

---

site_id	AC8
Number of Residues	8
Details	binding site for residue SO4 H 301

Chain	Residue
H	SER164
H	ASN204
H	ASP215
H	HOH420
H	HOH444
L	SER61
L	GLY62
L	HOH442

---

site_id	AC9
Number of Residues	4
Details	binding site for residue NA H 302

Chain	Residue
H	SER14
H	SER121
L	SO4301
L	HOH417

---

site_id	AD1
Number of Residues	5
Details	binding site for residue PGE H 303

Chain	Residue
H	GLN39
H	VAL93
H	GLN113
H	GLY114
L	GLY46

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
L	TYR197-HIS203

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI3
Number of Residues	1
Details	Site: {"description":"Not glycated","evidences":[{"source":"PubMed","id":"9326300","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine; by PDPK1","evidences":[{"source":"PubMed","id":"16443603","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19451179","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P10637","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (Glc) (glycation) lysine; in PHF-tau; in vitro","evidences":[{"source":"PubMed","id":"9326300","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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