Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4TO9

2.0A resolution structure of BfrB (N148L) from Pseudomonas aeruginosa

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004322	molecular_function	ferroxidase activity
A	0005506	molecular_function	iron ion binding
A	0005829	cellular_component	cytosol
A	0006826	biological_process	iron ion transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0006880	biological_process	intracellular sequestering of iron ion
A	0008199	molecular_function	ferric iron binding
A	0020037	molecular_function	heme binding
A	0046872	molecular_function	metal ion binding
A	0070288	cellular_component	ferritin complex
B	0004322	molecular_function	ferroxidase activity
B	0005506	molecular_function	iron ion binding
B	0005829	cellular_component	cytosol
B	0006826	biological_process	iron ion transport
B	0006879	biological_process	intracellular iron ion homeostasis
B	0006880	biological_process	intracellular sequestering of iron ion
B	0008199	molecular_function	ferric iron binding
B	0020037	molecular_function	heme binding
B	0046872	molecular_function	metal ion binding
B	0070288	cellular_component	ferritin complex
C	0004322	molecular_function	ferroxidase activity
C	0005506	molecular_function	iron ion binding
C	0005829	cellular_component	cytosol
C	0006826	biological_process	iron ion transport
C	0006879	biological_process	intracellular iron ion homeostasis
C	0006880	biological_process	intracellular sequestering of iron ion
C	0008199	molecular_function	ferric iron binding
C	0020037	molecular_function	heme binding
C	0046872	molecular_function	metal ion binding
C	0070288	cellular_component	ferritin complex
D	0004322	molecular_function	ferroxidase activity
D	0005506	molecular_function	iron ion binding
D	0005829	cellular_component	cytosol
D	0006826	biological_process	iron ion transport
D	0006879	biological_process	intracellular iron ion homeostasis
D	0006880	biological_process	intracellular sequestering of iron ion
D	0008199	molecular_function	ferric iron binding
D	0020037	molecular_function	heme binding
D	0046872	molecular_function	metal ion binding
D	0070288	cellular_component	ferritin complex
E	0004322	molecular_function	ferroxidase activity
E	0005506	molecular_function	iron ion binding
E	0005829	cellular_component	cytosol
E	0006826	biological_process	iron ion transport
E	0006879	biological_process	intracellular iron ion homeostasis
E	0006880	biological_process	intracellular sequestering of iron ion
E	0008199	molecular_function	ferric iron binding
E	0020037	molecular_function	heme binding
E	0046872	molecular_function	metal ion binding
E	0070288	cellular_component	ferritin complex
F	0004322	molecular_function	ferroxidase activity
F	0005506	molecular_function	iron ion binding
F	0005829	cellular_component	cytosol
F	0006826	biological_process	iron ion transport
F	0006879	biological_process	intracellular iron ion homeostasis
F	0006880	biological_process	intracellular sequestering of iron ion
F	0008199	molecular_function	ferric iron binding
F	0020037	molecular_function	heme binding
F	0046872	molecular_function	metal ion binding
F	0070288	cellular_component	ferritin complex
G	0004322	molecular_function	ferroxidase activity
G	0005506	molecular_function	iron ion binding
G	0005829	cellular_component	cytosol
G	0006826	biological_process	iron ion transport
G	0006879	biological_process	intracellular iron ion homeostasis
G	0006880	biological_process	intracellular sequestering of iron ion
G	0008199	molecular_function	ferric iron binding
G	0020037	molecular_function	heme binding
G	0046872	molecular_function	metal ion binding
G	0070288	cellular_component	ferritin complex
H	0004322	molecular_function	ferroxidase activity
H	0005506	molecular_function	iron ion binding
H	0005829	cellular_component	cytosol
H	0006826	biological_process	iron ion transport
H	0006879	biological_process	intracellular iron ion homeostasis
H	0006880	biological_process	intracellular sequestering of iron ion
H	0008199	molecular_function	ferric iron binding
H	0020037	molecular_function	heme binding
H	0046872	molecular_function	metal ion binding
H	0070288	cellular_component	ferritin complex
I	0004322	molecular_function	ferroxidase activity
I	0005506	molecular_function	iron ion binding
I	0005829	cellular_component	cytosol
I	0006826	biological_process	iron ion transport
I	0006879	biological_process	intracellular iron ion homeostasis
I	0006880	biological_process	intracellular sequestering of iron ion
I	0008199	molecular_function	ferric iron binding
I	0020037	molecular_function	heme binding
I	0046872	molecular_function	metal ion binding
I	0070288	cellular_component	ferritin complex
J	0004322	molecular_function	ferroxidase activity
J	0005506	molecular_function	iron ion binding
J	0005829	cellular_component	cytosol
J	0006826	biological_process	iron ion transport
J	0006879	biological_process	intracellular iron ion homeostasis
J	0006880	biological_process	intracellular sequestering of iron ion
J	0008199	molecular_function	ferric iron binding
J	0020037	molecular_function	heme binding
J	0046872	molecular_function	metal ion binding
J	0070288	cellular_component	ferritin complex
K	0004322	molecular_function	ferroxidase activity
K	0005506	molecular_function	iron ion binding
K	0005829	cellular_component	cytosol
K	0006826	biological_process	iron ion transport
K	0006879	biological_process	intracellular iron ion homeostasis
K	0006880	biological_process	intracellular sequestering of iron ion
K	0008199	molecular_function	ferric iron binding
K	0020037	molecular_function	heme binding
K	0046872	molecular_function	metal ion binding
K	0070288	cellular_component	ferritin complex
L	0004322	molecular_function	ferroxidase activity
L	0005506	molecular_function	iron ion binding
L	0005829	cellular_component	cytosol
L	0006826	biological_process	iron ion transport
L	0006879	biological_process	intracellular iron ion homeostasis
L	0006880	biological_process	intracellular sequestering of iron ion
L	0008199	molecular_function	ferric iron binding
L	0020037	molecular_function	heme binding
L	0046872	molecular_function	metal ion binding
L	0070288	cellular_component	ferritin complex
M	0004322	molecular_function	ferroxidase activity
M	0005506	molecular_function	iron ion binding
M	0005829	cellular_component	cytosol
M	0006826	biological_process	iron ion transport
M	0006879	biological_process	intracellular iron ion homeostasis
M	0006880	biological_process	intracellular sequestering of iron ion
M	0008199	molecular_function	ferric iron binding
M	0020037	molecular_function	heme binding
M	0046872	molecular_function	metal ion binding
M	0070288	cellular_component	ferritin complex
N	0004322	molecular_function	ferroxidase activity
N	0005506	molecular_function	iron ion binding
N	0005829	cellular_component	cytosol
N	0006826	biological_process	iron ion transport
N	0006879	biological_process	intracellular iron ion homeostasis
N	0006880	biological_process	intracellular sequestering of iron ion
N	0008199	molecular_function	ferric iron binding
N	0020037	molecular_function	heme binding
N	0046872	molecular_function	metal ion binding
N	0070288	cellular_component	ferritin complex
O	0004322	molecular_function	ferroxidase activity
O	0005506	molecular_function	iron ion binding
O	0005829	cellular_component	cytosol
O	0006826	biological_process	iron ion transport
O	0006879	biological_process	intracellular iron ion homeostasis
O	0006880	biological_process	intracellular sequestering of iron ion
O	0008199	molecular_function	ferric iron binding
O	0020037	molecular_function	heme binding
O	0046872	molecular_function	metal ion binding
O	0070288	cellular_component	ferritin complex
P	0004322	molecular_function	ferroxidase activity
P	0005506	molecular_function	iron ion binding
P	0005829	cellular_component	cytosol
P	0006826	biological_process	iron ion transport
P	0006879	biological_process	intracellular iron ion homeostasis
P	0006880	biological_process	intracellular sequestering of iron ion
P	0008199	molecular_function	ferric iron binding
P	0020037	molecular_function	heme binding
P	0046872	molecular_function	metal ion binding
P	0070288	cellular_component	ferritin complex
Q	0004322	molecular_function	ferroxidase activity
Q	0005506	molecular_function	iron ion binding
Q	0005829	cellular_component	cytosol
Q	0006826	biological_process	iron ion transport
Q	0006879	biological_process	intracellular iron ion homeostasis
Q	0006880	biological_process	intracellular sequestering of iron ion
Q	0008199	molecular_function	ferric iron binding
Q	0020037	molecular_function	heme binding
Q	0046872	molecular_function	metal ion binding
Q	0070288	cellular_component	ferritin complex
R	0004322	molecular_function	ferroxidase activity
R	0005506	molecular_function	iron ion binding
R	0005829	cellular_component	cytosol
R	0006826	biological_process	iron ion transport
R	0006879	biological_process	intracellular iron ion homeostasis
R	0006880	biological_process	intracellular sequestering of iron ion
R	0008199	molecular_function	ferric iron binding
R	0020037	molecular_function	heme binding
R	0046872	molecular_function	metal ion binding
R	0070288	cellular_component	ferritin complex
S	0004322	molecular_function	ferroxidase activity
S	0005506	molecular_function	iron ion binding
S	0005829	cellular_component	cytosol
S	0006826	biological_process	iron ion transport
S	0006879	biological_process	intracellular iron ion homeostasis
S	0006880	biological_process	intracellular sequestering of iron ion
S	0008199	molecular_function	ferric iron binding
S	0020037	molecular_function	heme binding
S	0046872	molecular_function	metal ion binding
S	0070288	cellular_component	ferritin complex
T	0004322	molecular_function	ferroxidase activity
T	0005506	molecular_function	iron ion binding
T	0005829	cellular_component	cytosol
T	0006826	biological_process	iron ion transport
T	0006879	biological_process	intracellular iron ion homeostasis
T	0006880	biological_process	intracellular sequestering of iron ion
T	0008199	molecular_function	ferric iron binding
T	0020037	molecular_function	heme binding
T	0046872	molecular_function	metal ion binding
T	0070288	cellular_component	ferritin complex
U	0004322	molecular_function	ferroxidase activity
U	0005506	molecular_function	iron ion binding
U	0005829	cellular_component	cytosol
U	0006826	biological_process	iron ion transport
U	0006879	biological_process	intracellular iron ion homeostasis
U	0006880	biological_process	intracellular sequestering of iron ion
U	0008199	molecular_function	ferric iron binding
U	0020037	molecular_function	heme binding
U	0046872	molecular_function	metal ion binding
U	0070288	cellular_component	ferritin complex
V	0004322	molecular_function	ferroxidase activity
V	0005506	molecular_function	iron ion binding
V	0005829	cellular_component	cytosol
V	0006826	biological_process	iron ion transport
V	0006879	biological_process	intracellular iron ion homeostasis
V	0006880	biological_process	intracellular sequestering of iron ion
V	0008199	molecular_function	ferric iron binding
V	0020037	molecular_function	heme binding
V	0046872	molecular_function	metal ion binding
V	0070288	cellular_component	ferritin complex
W	0004322	molecular_function	ferroxidase activity
W	0005506	molecular_function	iron ion binding
W	0005829	cellular_component	cytosol
W	0006826	biological_process	iron ion transport
W	0006879	biological_process	intracellular iron ion homeostasis
W	0006880	biological_process	intracellular sequestering of iron ion
W	0008199	molecular_function	ferric iron binding
W	0020037	molecular_function	heme binding
W	0046872	molecular_function	metal ion binding
W	0070288	cellular_component	ferritin complex
X	0004322	molecular_function	ferroxidase activity
X	0005506	molecular_function	iron ion binding
X	0005829	cellular_component	cytosol
X	0006826	biological_process	iron ion transport
X	0006879	biological_process	intracellular iron ion homeostasis
X	0006880	biological_process	intracellular sequestering of iron ion
X	0008199	molecular_function	ferric iron binding
X	0020037	molecular_function	heme binding
X	0046872	molecular_function	metal ion binding
X	0070288	cellular_component	ferritin complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue K A 201

Chain	Residue
A	GLN151
L	GLN151
M	GLN151
M	HOH263
X	GLN151

site_id	AC2
Number of Residues	22
Details	binding site for residue HEM B 201

Chain	Residue
A	TYR45
A	ILE49
A	MET52
A	LYS53
A	ILE59
A	LEU71
B	LEU19
B	ILE22
B	ASN23
B	PHE26
B	TYR45
B	ILE49
B	MET52
B	ILE59
B	HOH340
B	HOH366
B	HOH385
B	HOH390
A	LEU19
A	ILE22
A	ASN23
A	PHE26

site_id	AC3
Number of Residues	23
Details	binding site for residue HEM C 201

Chain	Residue
C	LEU19
C	ILE22
C	ASN23
C	PHE26
C	TYR45
C	ILE49
C	MET52
C	LYS53
C	ILE59
C	HOH320
C	HOH330
C	HOH353
C	HOH398
C	HOH410
D	LEU19
D	ILE22
D	ASN23
D	PHE26
D	TYR45
D	ILE49
D	MET52
D	LYS53
D	ILE59

site_id	AC4
Number of Residues	5
Details	binding site for residue K E 201

Chain	Residue
E	GLN151
J	GLN151
Q	GLN151
V	GLN151
V	HOH362

site_id	AC5
Number of Residues	22
Details	binding site for residue HEM F 201

Chain	Residue
E	LEU19
E	ILE22
E	ASN23
E	PHE26
E	TYR45
E	ILE49
E	MET52
E	ALA55
E	ILE59
F	LEU19
F	ILE22
F	ASN23
F	PHE26
F	TYR45
F	ILE49
F	MET52
F	LYS53
F	ALA55
F	ILE59
F	HOH323
F	HOH355
F	HOH368

site_id	AC6
Number of Residues	21
Details	binding site for residue HEM H 201

Chain	Residue
G	ILE22
G	ASN23
G	PHE26
G	TYR45
G	ILE49
G	MET52
G	LYS53
G	ILE59
H	LEU19
H	ILE22
H	ASN23
H	PHE26
H	TYR45
H	ILE49
H	MET52
H	LYS53
H	ILE59
H	HOH343
H	HOH385
H	HOH405
H	HOH417

site_id	AC7
Number of Residues	5
Details	binding site for residue K H 202

Chain	Residue
D	GLN151
D	HOH278
F	GLN151
H	GLN151
B	GLN151

site_id	AC8
Number of Residues	18
Details	binding site for residue HEM J 201

Chain	Residue
I	LEU19
I	ILE22
I	ASN23
I	PHE26
I	TYR45
I	ILE49
I	MET52
I	LYS53
I	ILE59
J	LEU19
J	ASN23
J	PHE26
J	TYR45
J	MET52
J	LYS53
J	ILE59
J	HOH376
J	HOH400

site_id	AC9
Number of Residues	22
Details	binding site for residue HEM K 201

Chain	Residue
K	LEU19
K	ASN23
K	PHE26
K	TYR45
K	ILE49
K	MET52
K	LYS53
K	ALA55
K	ILE59
K	HOH319
K	HOH336
K	HOH376
K	HOH391
L	LEU19
L	ILE22
L	ASN23
L	PHE26
L	TYR45
L	ILE49
L	MET52
L	LYS53
L	ILE59

site_id	AD1
Number of Residues	24
Details	binding site for residue HEM N 201

Chain	Residue
M	LEU19
M	ILE22
M	ASN23
M	PHE26
M	TYR45
M	ILE49
M	MET52
M	ALA55
M	ILE59
M	LEU71
N	LEU19
N	ILE22
N	ASN23
N	PHE26
N	TYR45
N	ILE49
N	MET52
N	LYS53
N	HOH342
N	HOH349
N	HOH352
N	HOH388
N	HOH389
N	HOH390

site_id	AD2
Number of Residues	19
Details	binding site for residue HEM O 201

Chain	Residue
O	LEU19
O	ASN23
O	PHE26
O	TYR45
O	ILE49
O	MET52
O	LYS53
O	ILE59
O	HOH359
O	HOH377
O	HOH378
O	HOH385
P	LEU19
P	ILE22
P	ASN23
P	PHE26
P	TYR45
P	ILE49
P	MET52

site_id	AD3
Number of Residues	5
Details	binding site for residue K O 202

Chain	Residue
G	GLN151
I	GLN151
O	GLN151
O	HOH369
W	GLN151

site_id	AD4
Number of Residues	19
Details	binding site for residue HEM Q 201

Chain	Residue
Q	LEU19
Q	ILE22
Q	ASN23
Q	PHE26
Q	TYR45
Q	ILE49
Q	MET52
Q	LYS53
Q	ILE59
Q	HOH319
Q	HOH373
R	LEU19
R	ILE22
R	ASN23
R	PHE26
R	TYR45
R	ILE49
R	MET52
R	ILE59

site_id	AD5
Number of Residues	5
Details	binding site for residue K R 201

Chain	Residue
N	GLN151
N	HOH375
P	GLN151
R	GLN151
T	GLN151

site_id	AD6
Number of Residues	22
Details	binding site for residue HEM S 201

Chain	Residue
S	LEU19
S	ILE22
S	ASN23
S	PHE26
S	TYR45
S	ILE49
S	MET52
S	LYS53
S	ILE59
S	HOH334
S	HOH338
S	HOH353
S	HOH402
T	LEU19
T	ILE22
T	ASN23
T	PHE26
T	TYR45
T	ILE49
T	MET52
T	LYS53
T	ILE59

site_id	AD7
Number of Residues	5
Details	binding site for residue K S 202

Chain	Residue
C	GLN151
K	GLN151
S	GLN151
S	HOH359
U	GLN151

site_id	AD8
Number of Residues	19
Details	binding site for residue HEM V 201

Chain	Residue
U	ILE22
U	ASN23
U	PHE26
U	TYR45
U	ILE49
U	MET52
U	ILE59
V	LEU19
V	ILE22
V	ASN23
V	PHE26
V	TYR45
V	ILE49
V	MET52
V	ILE59
V	HOH346
V	HOH382
V	HOH389
V	HOH397

site_id	AD9
Number of Residues	18
Details	binding site for residue HEM W 201

Chain	Residue
W	LEU19
W	ASN23
W	PHE26
W	TYR45
W	ILE49
W	MET52
W	ALA55
W	HOH352
W	HOH395
W	HOH399
X	LEU19
X	ILE22
X	ASN23
X	PHE26
X	TYR45
X	ILE49
X	MET52
X	ILE59

Functional Information from PROSITE/UniProt

site_id	PS00549
Number of Residues	19
Details	BACTERIOFERRITIN Bacterioferritin signature. MkGdkkVIqhLnkiLgneL

Chain	Residue	Details
A	MET1-LEU19

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)