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4TN5

Crystal Structure of Predicted Fructose Specific IIB from Escherichia Coli

Replaces:  4JXD
Functional Information from GO Data
ChainGOidnamespacecontents
A0005737cellular_componentcytoplasm
A0008982molecular_functionprotein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A0009401biological_processphosphoenolpyruvate-dependent sugar phosphotransferase system
A0016301molecular_functionkinase activity
A0016740molecular_functiontransferase activity
A0022877molecular_functionprotein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A0090582molecular_functionprotein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
A1990539biological_processfructose import across plasma membrane
B0005737cellular_componentcytoplasm
B0008982molecular_functionprotein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B0009401biological_processphosphoenolpyruvate-dependent sugar phosphotransferase system
B0016301molecular_functionkinase activity
B0016740molecular_functiontransferase activity
B0022877molecular_functionprotein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B0090582molecular_functionprotein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
B1990539biological_processfructose import across plasma membrane
Functional Information from PDB Data
site_idAC1
Number of Residues4
Detailsbinding site for residue NI A 201
ChainResidue
AHIS109
BHIS109
BHOH206
BHOH207

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsActive site: {"description":"Phosphocysteine intermediate","evidences":[{"source":"UniProtKB","id":"P20966","evidenceCode":"ECO:0000250"},{"evidenceCode":"ECO:0000305"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues2
DetailsModified residue: {"description":"Phosphocysteine; by EIIA","evidences":[{"source":"PROSITE-ProRule","id":"PRU00422","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

250359

PDB entries from 2026-03-11

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