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4TMZ

Translation initiation factor eIF5B (517-858) from C. thermophilum, bound to GTPgammaS and potassium

Functional Information from GO Data
ChainGOidnamespacecontents
A0003924molecular_functionGTPase activity
A0005525molecular_functionGTP binding
B0003924molecular_functionGTPase activity
B0005525molecular_functionGTP binding
Functional Information from PDB Data
site_idAC1
Number of Residues23
Detailsbinding site for residue GSP B 901
ChainResidue
BVAL532
BTHR557
BGLY597
BASN648
BLYS649
BASP651
BARG652
BSER716
BALA717
BHIS718
BMG902
BASP533
BK903
BHOH1013
BHOH1014
BHOH1015
BTHR534
BGLY535
BLYS536
BTHR537
BLYS538
BGLN549
BILE556

site_idAC2
Number of Residues5
Detailsbinding site for residue MG B 902
ChainResidue
BTHR537
BTHR557
BGSP901
BHOH1013
BHOH1014

site_idAC3
Number of Residues5
Detailsbinding site for residue K B 903
ChainResidue
BASP533
BGLY555
BGSP901
BHOH1016
BHOH1104

site_idAC4
Number of Residues5
Detailsbinding site for residue GOL B 904
ChainResidue
BARG680
BASP684
BGLU702
BTYR709
BHOH1001

site_idAC5
Number of Residues2
Detailsbinding site for residue CL B 905
ChainResidue
BPHE643
BARG737

site_idAC6
Number of Residues2
Detailsbinding site for residue CL B 906
ChainResidue
BARG803
BGLU804

site_idAC7
Number of Residues22
Detailsbinding site for residue GSP A 901
ChainResidue
AVAL532
AASP533
ATHR534
AGLY535
ALYS536
ATHR537
ALYS538
AGLN549
AILE556
ATHR557
AGLY597
AASN648
ALYS649
AASP651
AARG652
ASER716
AALA717
AHIS718
AMG902
AK903
AHOH1006
AHOH1007

site_idAC8
Number of Residues5
Detailsbinding site for residue MG A 902
ChainResidue
ATHR537
ATHR557
AGSP901
AHOH1006
AHOH1007

site_idAC9
Number of Residues5
Detailsbinding site for residue K A 903
ChainResidue
AASP533
AGLY555
AGSP901
AHOH1010
AHOH1052

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:25225612, ECO:0007744|PDB:4TMV, ECO:0007744|PDB:4TMW, ECO:0007744|PDB:4TMX
ChainResidueDetails
BASP533
BGLY555
AASP533
AGLY555

site_idSWS_FT_FI2
Number of Residues6
DetailsBINDING: BINDING => ECO:0000269|PubMed:25225612
ChainResidueDetails
BTHR537
BGLN549
BTHR557
ATHR537
AGLN549
ATHR557

site_idSWS_FT_FI3
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:24686316, ECO:0000269|PubMed:25225612
ChainResidueDetails
BASN648
BALA717
AASN648
AALA717

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PDB entries from 2024-11-13

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