4TMV
Translation initiation factor eIF5B (517-858) from C. thermophilum, bound to GTPgammaS and Sodium
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 27 |
| Details | binding site for residue GSP B 901 |
| Chain | Residue |
| B | VAL532 |
| B | ILE556 |
| B | THR557 |
| B | GLY597 |
| B | ASN648 |
| B | LYS649 |
| B | ASP651 |
| B | ARG652 |
| B | SER716 |
| B | ALA717 |
| B | HIS718 |
| B | ASP533 |
| B | MG902 |
| B | NA903 |
| B | HOH1074 |
| B | HOH1075 |
| B | HOH1126 |
| B | HOH1159 |
| B | HOH1162 |
| B | HOH1224 |
| B | THR534 |
| B | GLY535 |
| B | LYS536 |
| B | THR537 |
| B | LYS538 |
| B | GLN549 |
| B | GLY555 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 902 |
| Chain | Residue |
| B | THR537 |
| B | THR557 |
| B | GSP901 |
| B | HOH1074 |
| B | HOH1075 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue NA B 903 |
| Chain | Residue |
| B | ASP533 |
| B | GLY555 |
| B | GSP901 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 904 |
| Chain | Residue |
| B | ARG522 |
| B | LEU611 |
| B | ASN613 |
| B | SER770 |
| B | ASN771 |
| B | HOH1206 |
| B | HOH1294 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 905 |
| Chain | Residue |
| B | ARG639 |
| B | LYS640 |
| B | PRO642 |
| B | ARG737 |
| B | MET738 |
| B | ALA739 |
| B | HOH1107 |
| B | HOH1244 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 906 |
| Chain | Residue |
| B | HIS814 |
| B | GLU816 |
| B | VAL817 |
| B | HOH1110 |
| B | HOH1153 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 907 |
| Chain | Residue |
| B | LEU748 |
| B | GLY772 |
| B | ILE773 |
| B | ARG775 |
| B | HOH1140 |
| B | HOH1155 |
| site_id | AC8 |
| Number of Residues | 26 |
| Details | binding site for residue GSP A 901 |
| Chain | Residue |
| A | VAL532 |
| A | ASP533 |
| A | THR534 |
| A | GLY535 |
| A | LYS536 |
| A | THR537 |
| A | LYS538 |
| A | GLN549 |
| A | GLY555 |
| A | ILE556 |
| A | THR557 |
| A | GLY597 |
| A | ASN648 |
| A | LYS649 |
| A | ASP651 |
| A | SER716 |
| A | ALA717 |
| A | HIS718 |
| A | MG902 |
| A | NA903 |
| A | HOH1057 |
| A | HOH1058 |
| A | HOH1100 |
| A | HOH1159 |
| A | HOH1170 |
| A | HOH1235 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 902 |
| Chain | Residue |
| A | THR537 |
| A | THR557 |
| A | GSP901 |
| A | HOH1057 |
| A | HOH1058 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue NA A 903 |
| Chain | Residue |
| A | ASP533 |
| A | GLY555 |
| A | GSP901 |
| site_id | AD2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 904 |
| Chain | Residue |
| A | HOH1064 |
| A | HOH1103 |
| A | HOH1193 |
| B | HOH1097 |
| A | LYS542 |
| A | ILE543 |
| A | GLN545 |
| A | LYS573 |
| site_id | AD3 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 905 |
| Chain | Residue |
| A | ARG779 |
| A | VAL842 |
| A | GLY843 |
| A | PRO844 |
| A | GLU848 |
| A | HOH1005 |
| A | HOH1024 |
| A | HOH1025 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 906 |
| Chain | Residue |
| A | ARG779 |
| A | LYS790 |
| A | THR791 |
| A | PRO828 |
| A | HOH1011 |
| A | HOH1123 |
| A | HOH1284 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 442 |
| Details | Domain: {"description":"tr-type G","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 14 |
| Details | Region: {"description":"G1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Region: {"description":"G2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Region: {"description":"G3","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Region: {"description":"G4","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Region: {"description":"G5","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24686316","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25225612","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25225612","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4TMV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4TMW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4TMX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25225612","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
