Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4TM3

Kutzneria sp. 744 ornithine N-hydroxylase, KtzI-FADox-Br

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004497	molecular_function	monooxygenase activity
A	0016491	molecular_function	oxidoreductase activity
A	0047091	molecular_function	L-lysine 6-monooxygenase (NADPH) activity
B	0000166	molecular_function	nucleotide binding
B	0004497	molecular_function	monooxygenase activity
B	0016491	molecular_function	oxidoreductase activity
B	0047091	molecular_function	L-lysine 6-monooxygenase (NADPH) activity
C	0000166	molecular_function	nucleotide binding
C	0004497	molecular_function	monooxygenase activity
C	0016491	molecular_function	oxidoreductase activity
C	0047091	molecular_function	L-lysine 6-monooxygenase (NADPH) activity
D	0000166	molecular_function	nucleotide binding
D	0004497	molecular_function	monooxygenase activity
D	0016491	molecular_function	oxidoreductase activity
D	0047091	molecular_function	L-lysine 6-monooxygenase (NADPH) activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	30
Details	binding site for residue FAD A 501

Chain	Residue
A	GLY18
A	HIS51
A	MET54
A	SER126
A	GLU127
A	VAL128
A	SER163
A	THR164
A	GLY165
A	LEU166
A	TYR276
A	GLY20
A	TYR346
A	SER403
A	LEU405
A	BR503
A	HOH604
A	HOH625
A	HOH629
A	HOH643
A	HOH648
A	HOH651
A	PRO21
A	HOH694
A	ALA22
A	PHE42
A	GLU43
A	ARG44
A	ARG45
A	TRP50

site_id	AC2
Number of Residues	1
Details	binding site for residue BR A 502

Chain	Residue
A	LEU91

site_id	AC3
Number of Residues	4
Details	binding site for residue BR A 503

Chain	Residue
A	SER183
A	SER209
A	TYR346
A	FAD501

site_id	AC4
Number of Residues	3
Details	binding site for residue BR A 504

Chain	Residue
A	SER64
A	LYS67
B	HIS98

site_id	AC5
Number of Residues	2
Details	binding site for residue BR A 505

Chain	Residue
A	TYR276
A	LEU405

site_id	AC6
Number of Residues	4
Details	binding site for residue BR A 506

Chain	Residue
A	ARG374
A	TYR376
A	ASN407
A	GLU414

site_id	AC7
Number of Residues	2
Details	binding site for residue BR A 507

Chain	Residue
A	HIS182
A	HIS189

site_id	AC8
Number of Residues	1
Details	binding site for residue BR A 508

Chain	Residue
A	GLY413

site_id	AC9
Number of Residues	1
Details	binding site for residue BR A 509

Chain	Residue
A	ARG78

site_id	AD1
Number of Residues	2
Details	binding site for residue BR A 510

Chain	Residue
A	ARG105
A	ARG191

site_id	AD2
Number of Residues	2
Details	binding site for residue BR A 511

Chain	Residue
A	PHE100
B	HOH690

site_id	AD3
Number of Residues	2
Details	binding site for residue BR A 512

Chain	Residue
A	ASP177
A	PHE179

site_id	AD4
Number of Residues	1
Details	binding site for residue BR A 513

Chain	Residue
A	LEU307

site_id	AD5
Number of Residues	3
Details	binding site for residue BR A 514

Chain	Residue
A	ASP249
A	PRO250
A	ALA251

site_id	AD6
Number of Residues	1
Details	binding site for residue BR A 515

Chain	Residue
A	GLU295

site_id	AD7
Number of Residues	28
Details	binding site for residue FAD B 501

Chain	Residue
B	GLY18
B	GLY20
B	PRO21
B	ALA22
B	PHE42
B	GLU43
B	ARG44
B	ARG45
B	TRP50
B	HIS51
B	MET54
B	SER126
B	VAL128
B	SER163
B	THR164
B	GLY165
B	LEU166
B	TYR276
B	TYR346
B	SER403
B	LEU404
B	LEU405
B	BR503
B	BR505
B	HOH611
B	HOH618
B	HOH662
B	HOH682

site_id	AD8
Number of Residues	3
Details	binding site for residue BR B 502

Chain	Residue
B	GLY89
B	LEU91
B	VAL92

site_id	AD9
Number of Residues	3
Details	binding site for residue BR B 503

Chain	Residue
B	TYR276
B	LEU405
B	FAD501

site_id	AE1
Number of Residues	1
Details	binding site for residue BR B 504

Chain	Residue
B	HOH703

site_id	AE2
Number of Residues	4
Details	binding site for residue BR B 505

Chain	Residue
B	SER183
B	SER209
B	TYR346
B	FAD501

site_id	AE3
Number of Residues	3
Details	binding site for residue BR B 506

Chain	Residue
B	SER64
B	LYS67
A	HIS98

site_id	AE4
Number of Residues	4
Details	binding site for residue BR B 507

Chain	Residue
B	ARG374
B	TYR376
B	ASN407
B	GLU414

site_id	AE5
Number of Residues	3
Details	binding site for residue BR B 508

Chain	Residue
A	ASN303
A	TYR333
B	ARG385

site_id	AE6
Number of Residues	4
Details	binding site for residue BR B 509

Chain	Residue
B	SER176
B	HIS182
B	ARG185
B	HIS189

site_id	AE7
Number of Residues	2
Details	binding site for residue BR B 510

Chain	Residue
B	PHE100
B	HOH690

site_id	AE8
Number of Residues	1
Details	binding site for residue BR B 511

Chain	Residue
B	LEU307

site_id	AE9
Number of Residues	3
Details	binding site for residue BR B 512

Chain	Residue
B	THR164
B	ASP350
B	LEU354

site_id	AF1
Number of Residues	29
Details	binding site for residue FAD C 501

Chain	Residue
C	GLY18
C	GLY20
C	PRO21
C	ALA22
C	PHE42
C	GLU43
C	ARG44
C	ARG45
C	TRP50
C	HIS51
C	MET54
C	SER126
C	GLU127
C	VAL128
C	SER163
C	THR164
C	GLY165
C	LEU166
C	TYR276
C	TYR346
C	SER403
C	LEU405
C	BR502
C	HOH616
C	HOH618
C	HOH625
C	HOH651
C	HOH691
C	HOH692

site_id	AF2
Number of Residues	3
Details	binding site for residue BR C 502

Chain	Residue
C	TYR276
C	LEU405
C	FAD501

site_id	AF3
Number of Residues	2
Details	binding site for residue BR C 503

Chain	Residue
C	LEU91
C	VAL92

site_id	AF4
Number of Residues	3
Details	binding site for residue BR C 504

Chain	Residue
C	SER183
C	SER209
C	TYR346

site_id	AF5
Number of Residues	3
Details	binding site for residue BR C 505

Chain	Residue
C	SER64
C	LYS67
D	HIS98

site_id	AF6
Number of Residues	4
Details	binding site for residue BR C 506

Chain	Residue
C	ARG374
C	TYR376
C	ASN407
C	GLU414

site_id	AF7
Number of Residues	1
Details	binding site for residue BR C 508

Chain	Residue
C	TYR333

site_id	AF8
Number of Residues	2
Details	binding site for residue BR C 509

Chain	Residue
C	ASP99
C	PHE100

site_id	AF9
Number of Residues	29
Details	binding site for residue FAD D 501

Chain	Residue
D	GLY18
D	GLY20
D	PRO21
D	ALA22
D	PHE42
D	GLU43
D	ARG44
D	ARG45
D	TRP50
D	HIS51
D	MET54
D	SER126
D	VAL128
D	SER163
D	THR164
D	GLY165
D	LEU166
D	TYR276
D	TYR346
D	SER403
D	LEU405
D	BR504
D	HOH622
D	HOH637
D	HOH646
D	HOH657
D	HOH675
D	HOH691
D	HOH707

site_id	AG1
Number of Residues	3
Details	binding site for residue BR D 502

Chain	Residue
D	SER183
D	SER209
D	TYR346

site_id	AG2
Number of Residues	3
Details	binding site for residue BR D 503

Chain	Residue
D	GLY89
D	LEU91
D	VAL92

site_id	AG3
Number of Residues	3
Details	binding site for residue BR D 504

Chain	Residue
D	TYR276
D	LEU405
D	FAD501

site_id	AG4
Number of Residues	3
Details	binding site for residue BR D 505

Chain	Residue
C	HIS98
D	SER64
D	LYS67

site_id	AG5
Number of Residues	4
Details	binding site for residue BR D 506

Chain	Residue
D	SER176
D	TRP181
D	HIS182
D	HIS189

site_id	AG6
Number of Residues	4
Details	binding site for residue BR D 508

Chain	Residue
D	ARG374
D	TYR376
D	ASN407
D	GLU414

site_id	AG7
Number of Residues	2
Details	binding site for residue BR D 510

Chain	Residue
D	PRO250
D	ALA251

site_id	AG8
Number of Residues	1
Details	binding site for residue BR D 511

Chain	Residue
D	PHE100

site_id	AG9
Number of Residues	1
Details	binding site for residue BR D 512

Chain	Residue
D	PHE179

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)