4TLZ
Kutzneria sp. 744 ornithine N-hydroxylase, KtzI-FADox-NADP+-L-orn
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0006879 | biological_process | intracellular iron ion homeostasis |
| A | 0044249 | biological_process | cellular biosynthetic process |
| A | 0047091 | molecular_function | L-lysine 6-monooxygenase (NADPH) activity |
| A | 1901566 | biological_process | organonitrogen compound biosynthetic process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0006879 | biological_process | intracellular iron ion homeostasis |
| B | 0044249 | biological_process | cellular biosynthetic process |
| B | 0047091 | molecular_function | L-lysine 6-monooxygenase (NADPH) activity |
| B | 1901566 | biological_process | organonitrogen compound biosynthetic process |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004497 | molecular_function | monooxygenase activity |
| C | 0006879 | biological_process | intracellular iron ion homeostasis |
| C | 0044249 | biological_process | cellular biosynthetic process |
| C | 0047091 | molecular_function | L-lysine 6-monooxygenase (NADPH) activity |
| C | 1901566 | biological_process | organonitrogen compound biosynthetic process |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0004497 | molecular_function | monooxygenase activity |
| D | 0006879 | biological_process | intracellular iron ion homeostasis |
| D | 0044249 | biological_process | cellular biosynthetic process |
| D | 0047091 | molecular_function | L-lysine 6-monooxygenase (NADPH) activity |
| D | 1901566 | biological_process | organonitrogen compound biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 34 |
| Details | binding site for residue FAD A 501 |
| Chain | Residue |
| A | GLY18 |
| A | HIS51 |
| A | MET54 |
| A | ARG104 |
| A | SER126 |
| A | GLU127 |
| A | VAL128 |
| A | SER163 |
| A | THR164 |
| A | GLY165 |
| A | LEU166 |
| A | GLY20 |
| A | ASN275 |
| A | TYR276 |
| A | TYR346 |
| A | SER403 |
| A | LEU404 |
| A | NAP502 |
| A | HOH608 |
| A | HOH609 |
| A | HOH611 |
| A | HOH612 |
| A | PRO21 |
| A | HOH658 |
| A | HOH682 |
| A | HOH713 |
| A | HOH714 |
| A | HOH762 |
| A | ALA22 |
| A | PHE42 |
| A | GLU43 |
| A | ARG44 |
| A | ARG45 |
| A | TRP50 |
| site_id | AC2 |
| Number of Residues | 27 |
| Details | binding site for residue NAP A 502 |
| Chain | Residue |
| A | LYS60 |
| A | GLN62 |
| A | ARG104 |
| A | PRO171 |
| A | GLY205 |
| A | GLY206 |
| A | GLY207 |
| A | GLN208 |
| A | SER209 |
| A | GLU212 |
| A | PRO231 |
| A | ASN275 |
| A | SER277 |
| A | HIS309 |
| A | VAL310 |
| A | ALA343 |
| A | THR344 |
| A | GLY345 |
| A | FAD501 |
| A | ORN503 |
| A | HOH624 |
| A | HOH625 |
| A | HOH636 |
| A | HOH666 |
| A | HOH682 |
| A | HOH700 |
| D | TYR270 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue ORN A 503 |
| Chain | Residue |
| A | GLN62 |
| A | VAL63 |
| A | LYS67 |
| A | ASN245 |
| A | PHE248 |
| A | ASN275 |
| A | SER406 |
| A | NAP502 |
| A | HOH717 |
| A | HOH718 |
| A | HOH719 |
| A | HOH720 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue K A 504 |
| Chain | Residue |
| A | LEU30 |
| A | GLU31 |
| A | SER33 |
| A | ALA35 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue K A 505 |
| Chain | Residue |
| A | GLU115 |
| A | SER116 |
| A | LEU118 |
| A | HIS120 |
| A | HOH650 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue K A 506 |
| Chain | Residue |
| A | SER116 |
| A | LEU118 |
| site_id | AC7 |
| Number of Residues | 29 |
| Details | binding site for residue FAD B 501 |
| Chain | Residue |
| B | LEU166 |
| B | ASN275 |
| B | TYR276 |
| B | TYR346 |
| B | SER403 |
| B | LEU404 |
| B | NAP502 |
| B | HOH620 |
| B | HOH621 |
| B | HOH624 |
| B | HOH685 |
| B | HOH724 |
| B | HOH744 |
| B | HOH750 |
| B | GLY18 |
| B | GLY20 |
| B | PRO21 |
| B | ALA22 |
| B | PHE42 |
| B | GLU43 |
| B | ARG44 |
| B | TRP50 |
| B | HIS51 |
| B | ARG104 |
| B | SER126 |
| B | VAL128 |
| B | SER163 |
| B | THR164 |
| B | GLY165 |
| site_id | AC8 |
| Number of Residues | 31 |
| Details | binding site for residue NAP B 502 |
| Chain | Residue |
| B | LYS60 |
| B | GLN62 |
| B | ARG104 |
| B | PRO171 |
| B | GLY205 |
| B | GLY206 |
| B | GLY207 |
| B | GLN208 |
| B | SER209 |
| B | GLU212 |
| B | ILE229 |
| B | PRO231 |
| B | ASN275 |
| B | SER277 |
| B | HIS309 |
| B | VAL310 |
| B | ALA343 |
| B | THR344 |
| B | GLY345 |
| B | TYR346 |
| B | FAD501 |
| B | ORN503 |
| B | HOH629 |
| B | HOH630 |
| B | HOH631 |
| B | HOH635 |
| B | HOH650 |
| B | HOH685 |
| B | HOH721 |
| B | HOH736 |
| C | TYR270 |
| site_id | AC9 |
| Number of Residues | 10 |
| Details | binding site for residue ORN B 503 |
| Chain | Residue |
| B | GLN62 |
| B | VAL63 |
| B | LYS67 |
| B | ASN245 |
| B | PHE248 |
| B | ASN275 |
| B | SER406 |
| B | NAP502 |
| B | HOH719 |
| B | HOH720 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue K B 504 |
| Chain | Residue |
| B | LEU30 |
| B | GLU31 |
| B | SER33 |
| B | ALA35 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue K B 505 |
| Chain | Residue |
| B | GLU115 |
| B | SER116 |
| B | LEU118 |
| B | HIS120 |
| B | HOH610 |
| site_id | AD3 |
| Number of Residues | 32 |
| Details | binding site for residue FAD C 501 |
| Chain | Residue |
| C | GLY18 |
| C | GLY20 |
| C | PRO21 |
| C | ALA22 |
| C | PHE42 |
| C | GLU43 |
| C | ARG44 |
| C | ARG45 |
| C | TRP50 |
| C | HIS51 |
| C | ARG104 |
| C | SER126 |
| C | GLU127 |
| C | VAL128 |
| C | SER163 |
| C | THR164 |
| C | GLY165 |
| C | LEU166 |
| C | ASN275 |
| C | TYR276 |
| C | TYR346 |
| C | SER403 |
| C | LEU404 |
| C | NAP502 |
| C | HOH623 |
| C | HOH624 |
| C | HOH626 |
| C | HOH627 |
| C | HOH628 |
| C | HOH701 |
| C | HOH723 |
| C | HOH726 |
| site_id | AD4 |
| Number of Residues | 31 |
| Details | binding site for residue NAP C 502 |
| Chain | Residue |
| B | TYR270 |
| C | LYS60 |
| C | GLN62 |
| C | ARG104 |
| C | PRO171 |
| C | GLY205 |
| C | GLY206 |
| C | GLY207 |
| C | GLN208 |
| C | SER209 |
| C | GLU212 |
| C | ILE229 |
| C | PRO231 |
| C | ASN275 |
| C | SER277 |
| C | HIS309 |
| C | VAL310 |
| C | ALA343 |
| C | THR344 |
| C | GLY345 |
| C | FAD501 |
| C | ORN503 |
| C | HOH611 |
| C | HOH617 |
| C | HOH618 |
| C | HOH619 |
| C | HOH669 |
| C | HOH691 |
| C | HOH694 |
| C | HOH700 |
| C | HOH726 |
| site_id | AD5 |
| Number of Residues | 12 |
| Details | binding site for residue ORN C 503 |
| Chain | Residue |
| C | GLN62 |
| C | VAL63 |
| C | LYS67 |
| C | ASN245 |
| C | PHE248 |
| C | ASN275 |
| C | SER406 |
| C | NAP502 |
| C | HOH695 |
| C | HOH696 |
| C | HOH698 |
| C | HOH699 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue K C 504 |
| Chain | Residue |
| C | LEU30 |
| C | GLU31 |
| C | SER33 |
| C | ALA35 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue K C 505 |
| Chain | Residue |
| C | GLU115 |
| C | LEU118 |
| C | HIS120 |
| C | GLU121 |
| site_id | AD8 |
| Number of Residues | 32 |
| Details | binding site for residue FAD D 501 |
| Chain | Residue |
| D | GLY18 |
| D | PHE19 |
| D | GLY20 |
| D | PRO21 |
| D | ALA22 |
| D | PHE42 |
| D | GLU43 |
| D | ARG44 |
| D | ARG45 |
| D | TRP50 |
| D | HIS51 |
| D | MET54 |
| D | ARG104 |
| D | SER126 |
| D | VAL128 |
| D | SER163 |
| D | THR164 |
| D | GLY165 |
| D | LEU166 |
| D | ASN275 |
| D | TYR276 |
| D | TYR346 |
| D | SER403 |
| D | LEU404 |
| D | NAP502 |
| D | HOH623 |
| D | HOH628 |
| D | HOH629 |
| D | HOH630 |
| D | HOH631 |
| D | HOH666 |
| D | HOH677 |
| site_id | AD9 |
| Number of Residues | 32 |
| Details | binding site for residue NAP D 502 |
| Chain | Residue |
| A | TYR270 |
| D | LYS60 |
| D | GLN62 |
| D | ARG104 |
| D | PRO171 |
| D | GLY205 |
| D | GLY206 |
| D | GLY207 |
| D | GLN208 |
| D | SER209 |
| D | GLU212 |
| D | ILE229 |
| D | PRO231 |
| D | ASN275 |
| D | SER277 |
| D | HIS309 |
| D | VAL310 |
| D | ALA343 |
| D | THR344 |
| D | GLY345 |
| D | TYR346 |
| D | FAD501 |
| D | ORN503 |
| D | HOH612 |
| D | HOH613 |
| D | HOH614 |
| D | HOH616 |
| D | HOH644 |
| D | HOH665 |
| D | HOH666 |
| D | HOH734 |
| D | HOH739 |
| site_id | AE1 |
| Number of Residues | 11 |
| Details | binding site for residue ORN D 503 |
| Chain | Residue |
| D | GLN62 |
| D | VAL63 |
| D | LYS67 |
| D | ASN245 |
| D | PHE248 |
| D | ASN275 |
| D | SER406 |
| D | NAP502 |
| D | HOH711 |
| D | HOH712 |
| D | HOH713 |
| site_id | AE2 |
| Number of Residues | 4 |
| Details | binding site for residue K D 504 |
| Chain | Residue |
| D | LEU30 |
| D | GLU31 |
| D | SER33 |
| D | ALA35 |
