4TLR

NS5b in complex with lactam-thiophene carboxylic acids

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0003968	molecular_function	RNA-dependent RNA polymerase activity
A	0039694	biological_process	viral RNA genome replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue 33H A 601

Chain	Residue
A	ARG422
A	HOH763
A	HOH774
A	HOH777
A	HOH1081
A	HIS475
A	SER476
A	TYR477
A	ILE482
A	ARG501
A	TRP528
A	HOH750
A	HOH757

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site_id	AC2
Number of Residues	16
Details	binding site for residue 79Z A 602

Chain	Residue
A	PHE193
A	PRO197
A	ARG200
A	LEU204
A	LEU314
A	CYS316
A	ASP319
A	VAL321
A	ILE363
A	SER365
A	CYS366
A	SER368
A	MET414
A	TYR415
A	TYR448
A	HOH1104

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