4S3E
IspG in complex with Inhibitor 7 (compound 1061)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0008299 | biological_process | isoprenoid biosynthetic process |
| A | 0016114 | biological_process | terpenoid biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019288 | biological_process | isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway |
| A | 0044237 | biological_process | cellular metabolic process |
| A | 0046429 | molecular_function | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity (ferredoxin) |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| A | 0141197 | molecular_function | 4-hydroxy-3-methylbut-2-enyl-diphosphate synthase activity (flavodoxin) |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SF4 A 901 |
| Chain | Residue |
| A | CYS297 |
| A | GLY299 |
| A | CYS300 |
| A | THR303 |
| A | GLY342 |
| A | CYS343 |
| A | 0CG902 |
| A | HOH1001 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 0CG A 902 |
| Chain | Residue |
| A | ARG56 |
| A | ARG110 |
| A | ARG141 |
| A | ASN145 |
| A | LYS204 |
| A | THR231 |
| A | ARG260 |
| A | SER262 |
| A | SF4901 |
| A | HOH1001 |
| A | HOH1060 |
| A | HOH1061 |
| A | HOH1346 |
| A | MET29 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 903 |
| Chain | Residue |
| A | THR155 |
| A | MET158 |
| A | ASP159 |
| A | LEU381 |
| A | GLU389 |
| A | ARG392 |
| A | HOH1110 |
| A | HOH1424 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 904 |
| Chain | Residue |
| A | GLU276 |
| A | GLN279 |
| A | GLU280 |
| A | GLN283 |
| A | PHE290 |
| A | ALA291 |
| A | HOH1097 |
| A | HOH1142 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 905 |
| Chain | Residue |
| A | ASN31 |
| A | GLN43 |
| A | ALA266 |
| A | GLY268 |
| A | GLU269 |
| A | ARG271 |
| A | GLN309 |
| A | HOH1267 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00159 |
| Chain | Residue | Details |
| A | CYS297 | |
| A | CYS300 | |
| A | CYS343 | |
| A | GLU350 |
