4S3E
IspG in complex with Inhibitor 7 (compound 1061)
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005506 | molecular_function | iron ion binding |
A | 0008299 | biological_process | isoprenoid biosynthetic process |
A | 0016114 | biological_process | terpenoid biosynthetic process |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0019288 | biological_process | isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway |
A | 0044237 | biological_process | cellular metabolic process |
A | 0046429 | molecular_function | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity (ferredoxin) |
A | 0046872 | molecular_function | metal ion binding |
A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
A | 0141197 | molecular_function | 4-hydroxy-3-methylbut-2-enyl-diphosphate synthase activity (flavodoxin) |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE SF4 A 901 |
Chain | Residue |
A | CYS297 |
A | GLY299 |
A | CYS300 |
A | THR303 |
A | GLY342 |
A | CYS343 |
A | 0CG902 |
A | HOH1001 |
site_id | AC2 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE 0CG A 902 |
Chain | Residue |
A | ARG56 |
A | ARG110 |
A | ARG141 |
A | ASN145 |
A | LYS204 |
A | THR231 |
A | ARG260 |
A | SER262 |
A | SF4901 |
A | HOH1001 |
A | HOH1060 |
A | HOH1061 |
A | HOH1346 |
A | MET29 |
site_id | AC3 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE GOL A 903 |
Chain | Residue |
A | THR155 |
A | MET158 |
A | ASP159 |
A | LEU381 |
A | GLU389 |
A | ARG392 |
A | HOH1110 |
A | HOH1424 |
site_id | AC4 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE GOL A 904 |
Chain | Residue |
A | GLU276 |
A | GLN279 |
A | GLU280 |
A | GLN283 |
A | PHE290 |
A | ALA291 |
A | HOH1097 |
A | HOH1142 |
site_id | AC5 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE GOL A 905 |
Chain | Residue |
A | ASN31 |
A | GLN43 |
A | ALA266 |
A | GLY268 |
A | GLU269 |
A | ARG271 |
A | GLN309 |
A | HOH1267 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00159 |
Chain | Residue | Details |
A | CYS297 | |
A | CYS300 | |
A | CYS343 | |
A | GLU350 |