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4RYE

The crystal structure of D-ALANYL-D-ALANINE CARBOXYPEPTIDASE from Mycobacterium tuberculosis H37Rv

Functional Information from GO Data
ChainGOidnamespacecontents
A0004180molecular_functioncarboxypeptidase activity
A0006508biological_processproteolysis
A0008233molecular_functionpeptidase activity
A0008360biological_processregulation of cell shape
A0009002molecular_functionserine-type D-Ala-D-Ala carboxypeptidase activity
A0009252biological_processpeptidoglycan biosynthetic process
A0016787molecular_functionhydrolase activity
A0042597cellular_componentperiplasmic space
A0071555biological_processcell wall organization
B0004180molecular_functioncarboxypeptidase activity
B0006508biological_processproteolysis
B0008233molecular_functionpeptidase activity
B0008360biological_processregulation of cell shape
B0009002molecular_functionserine-type D-Ala-D-Ala carboxypeptidase activity
B0009252biological_processpeptidoglycan biosynthetic process
B0016787molecular_functionhydrolase activity
B0042597cellular_componentperiplasmic space
B0071555biological_processcell wall organization
C0004180molecular_functioncarboxypeptidase activity
C0006508biological_processproteolysis
C0008233molecular_functionpeptidase activity
C0008360biological_processregulation of cell shape
C0009002molecular_functionserine-type D-Ala-D-Ala carboxypeptidase activity
C0009252biological_processpeptidoglycan biosynthetic process
C0016787molecular_functionhydrolase activity
C0042597cellular_componentperiplasmic space
C0071555biological_processcell wall organization
D0004180molecular_functioncarboxypeptidase activity
D0006508biological_processproteolysis
D0008233molecular_functionpeptidase activity
D0008360biological_processregulation of cell shape
D0009002molecular_functionserine-type D-Ala-D-Ala carboxypeptidase activity
D0009252biological_processpeptidoglycan biosynthetic process
D0016787molecular_functionhydrolase activity
D0042597cellular_componentperiplasmic space
D0071555biological_processcell wall organization
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsActive site: {"description":"Acyl-ester intermediate","evidences":[{"source":"PubMed","id":"25551456","evidenceCode":"ECO:0000305"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues4
DetailsActive site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"P0AEB2","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues4
DetailsActive site: {"evidences":[{"source":"UniProtKB","id":"P0AEB2","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

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PDB entries from 2025-12-24

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