4RVU
The native structure of mycobacterial Rv1454c complexed with NADPH
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003960 | molecular_function | quinone reductase (NADPH) activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0009274 | cellular_component | peptidoglycan-based cell wall |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0035925 | molecular_function | mRNA 3'-UTR AU-rich region binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003960 | molecular_function | quinone reductase (NADPH) activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005829 | cellular_component | cytosol |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0009274 | cellular_component | peptidoglycan-based cell wall |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0035925 | molecular_function | mRNA 3'-UTR AU-rich region binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0003960 | molecular_function | quinone reductase (NADPH) activity |
| C | 0005576 | cellular_component | extracellular region |
| C | 0005829 | cellular_component | cytosol |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0009274 | cellular_component | peptidoglycan-based cell wall |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0035925 | molecular_function | mRNA 3'-UTR AU-rich region binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0003960 | molecular_function | quinone reductase (NADPH) activity |
| D | 0005576 | cellular_component | extracellular region |
| D | 0005829 | cellular_component | cytosol |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0009274 | cellular_component | peptidoglycan-based cell wall |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0035925 | molecular_function | mRNA 3'-UTR AU-rich region binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 40 |
| Details | BINDING SITE FOR RESIDUE NDP A 401 |
| Chain | Residue |
| A | PHE41 |
| A | VAL173 |
| A | SER174 |
| A | LYS178 |
| A | TYR193 |
| A | GLY219 |
| A | PHE241 |
| A | GLY242 |
| A | ALA243 |
| A | ALA244 |
| A | SER245 |
| A | TYR45 |
| A | ARG266 |
| A | PRO267 |
| A | SER268 |
| A | LEU269 |
| A | LEU315 |
| A | GLU316 |
| A | ARG318 |
| A | HOH505 |
| A | HOH509 |
| A | HOH516 |
| A | LEU124 |
| A | HOH522 |
| A | HOH524 |
| A | HOH530 |
| A | HOH557 |
| A | HOH582 |
| A | HOH589 |
| A | HOH600 |
| A | HOH615 |
| A | HOH627 |
| A | HOH756 |
| A | THR128 |
| A | HOH779 |
| A | TYR131 |
| A | ALA149 |
| A | GLY152 |
| A | GLY153 |
| A | VAL154 |
| site_id | AC2 |
| Number of Residues | 37 |
| Details | BINDING SITE FOR RESIDUE NDP B 401 |
| Chain | Residue |
| B | PHE41 |
| B | TYR45 |
| B | LEU124 |
| B | LYS125 |
| B | THR128 |
| B | TYR131 |
| B | ALA149 |
| B | GLY152 |
| B | GLY153 |
| B | VAL154 |
| B | VAL173 |
| B | SER174 |
| B | LYS178 |
| B | TYR193 |
| B | GLY219 |
| B | VAL220 |
| B | PHE241 |
| B | GLY242 |
| B | ALA243 |
| B | ALA244 |
| B | SER245 |
| B | ARG266 |
| B | PRO267 |
| B | SER268 |
| B | LEU269 |
| B | GLU316 |
| B | ARG318 |
| B | HOH516 |
| B | HOH535 |
| B | HOH538 |
| B | HOH543 |
| B | HOH549 |
| B | HOH575 |
| B | HOH585 |
| B | HOH745 |
| B | HOH765 |
| B | HOH780 |
| site_id | AC3 |
| Number of Residues | 37 |
| Details | BINDING SITE FOR RESIDUE NDP C 401 |
| Chain | Residue |
| C | LEU269 |
| C | GLU316 |
| C | ARG318 |
| C | HOH505 |
| C | HOH506 |
| C | HOH507 |
| C | HOH516 |
| C | HOH521 |
| C | HOH525 |
| C | HOH535 |
| C | HOH543 |
| C | HOH547 |
| C | HOH548 |
| C | HOH563 |
| C | HOH584 |
| C | PHE41 |
| C | TYR45 |
| C | LEU124 |
| C | THR128 |
| C | TYR131 |
| C | ALA149 |
| C | GLY152 |
| C | GLY153 |
| C | VAL154 |
| C | VAL173 |
| C | SER174 |
| C | LYS178 |
| C | TYR193 |
| C | GLY219 |
| C | PHE241 |
| C | GLY242 |
| C | ALA243 |
| C | ALA244 |
| C | SER245 |
| C | ARG266 |
| C | PRO267 |
| C | SER268 |
| site_id | AC4 |
| Number of Residues | 37 |
| Details | BINDING SITE FOR RESIDUE NDP D 401 |
| Chain | Residue |
| D | PHE41 |
| D | TYR45 |
| D | LEU124 |
| D | THR128 |
| D | TYR131 |
| D | ALA149 |
| D | GLY152 |
| D | GLY153 |
| D | VAL154 |
| D | VAL173 |
| D | SER174 |
| D | LYS178 |
| D | TYR193 |
| D | GLY219 |
| D | VAL220 |
| D | PHE241 |
| D | GLY242 |
| D | ALA243 |
| D | ALA244 |
| D | SER245 |
| D | ARG266 |
| D | PRO267 |
| D | SER268 |
| D | LEU269 |
| D | GLU316 |
| D | ARG318 |
| D | HOH503 |
| D | HOH504 |
| D | HOH511 |
| D | HOH512 |
| D | HOH531 |
| D | HOH534 |
| D | HOH544 |
| D | HOH567 |
| D | HOH672 |
| D | HOH698 |
| D | HOH781 |
