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4RPT

The 1.35A structure of a viral RNase L antagonist reveals basis for the 2'-5'-oligoadenylate binding and enzyme activity.

Functional Information from PDB Data
site_idAC1
Number of Residues10
DetailsBINDING SITE FOR RESIDUE MLI A 1001
ChainResidue
AVAL767
BTYR754
ASER768
AGLY769
AVAL770
ALEU771
AILE795
APRO796
AHOH1128
AHOH1153

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE EDO A 1002
ChainResidue
APHE700
AHIS718
ATHR720
AHOH1187

site_idAC3
Number of Residues10
DetailsBINDING SITE FOR RESIDUE MLI B 1001
ChainResidue
ATYR754
BVAL767
BSER768
BGLY769
BVAL770
BLEU771
BILE795
BPRO796
BHOH1122
BHOH1161

site_idAC4
Number of Residues3
DetailsBINDING SITE FOR RESIDUE EDO B 1002
ChainResidue
BHIS718
BTHR720
BHOH1238

226707

PDB entries from 2024-10-30

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