4RPF
Crystal structure of homoserine kinase from Yersinia pestis Nepal516, NYSGRC target 032715
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004413 | molecular_function | homoserine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006566 | biological_process | L-threonine metabolic process |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009088 | biological_process | L-threonine biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004413 | molecular_function | homoserine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006566 | biological_process | L-threonine metabolic process |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009088 | biological_process | L-threonine biosynthetic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016740 | molecular_function | transferase activity |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004413 | molecular_function | homoserine kinase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006566 | biological_process | L-threonine metabolic process |
| C | 0008652 | biological_process | amino acid biosynthetic process |
| C | 0009088 | biological_process | L-threonine biosynthetic process |
| C | 0016301 | molecular_function | kinase activity |
| C | 0016740 | molecular_function | transferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE CIT A 401 |
| Chain | Residue |
| A | GLY93 |
| A | HIS139 |
| A | ASN142 |
| A | THR184 |
| A | GLY261 |
| A | SER262 |
| A | HOH502 |
| A | SER94 |
| A | GLY95 |
| A | LEU96 |
| A | GLY97 |
| A | SER98 |
| A | SER99 |
| A | ALA100 |
| A | GLU131 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE CIT B 401 |
| Chain | Residue |
| B | GLY93 |
| B | SER94 |
| B | GLY95 |
| B | LEU96 |
| B | GLY97 |
| B | SER98 |
| B | SER99 |
| B | ALA100 |
| B | GLU131 |
| B | HIS139 |
| B | ASN142 |
| B | THR184 |
| B | GLY261 |
| B | SER262 |
| B | HOH533 |
| B | HOH538 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE CIT C 401 |
| Chain | Residue |
| C | GLY93 |
| C | SER94 |
| C | GLY95 |
| C | LEU96 |
| C | GLY97 |
| C | SER98 |
| C | SER99 |
| C | ALA100 |
| C | GLU131 |
| C | HIS139 |
| C | ASN142 |
| C | THR184 |
| C | GLY261 |
| C | SER262 |
Functional Information from PROSITE/UniProt
| site_id | PS00627 |
| Number of Residues | 12 |
| Details | GHMP_KINASES_ATP GHMP kinases putative ATP-binding domain. MPiGsGLGSSAC |
| Chain | Residue | Details |
| A | MET90-CYS101 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 30 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00384","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
