4RNW
Truncated version of the G303 Circular Permutation of Old Yellow Enzyme
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE FMN A 401 |
| Chain | Residue |
| A | GLY24 |
| A | THR136 |
| A | GLY171 |
| A | GLN213 |
| A | HIS290 |
| A | ASN293 |
| A | ARG342 |
| A | EPE402 |
| A | EDO403 |
| A | HOH509 |
| A | HOH532 |
| A | ASN25 |
| A | HOH559 |
| A | HOH960 |
| A | TYR46 |
| A | GLY47 |
| A | ARG48 |
| A | TYR75 |
| A | PRO133 |
| A | PRO134 |
| A | LEU135 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE EPE A 402 |
| Chain | Residue |
| A | TYR75 |
| A | TYR181 |
| A | HIS290 |
| A | ASN293 |
| A | TYR295 |
| A | PHE349 |
| A | FMN401 |
| A | EDO403 |
| A | EDO409 |
| A | HOH646 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 403 |
| Chain | Residue |
| A | PHE349 |
| A | FMN401 |
| A | EPE402 |
| A | HOH640 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 404 |
| Chain | Residue |
| A | HIS80 |
| A | ASP84 |
| A | TYR85 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 405 |
| Chain | Residue |
| A | LYS373 |
| A | LYS376 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 406 |
| Chain | Residue |
| A | MET138 |
| A | TYR181 |
| A | ASP182 |
| A | ASN183 |
| A | PHE222 |
| A | ASN225 |
| A | EDO409 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 407 |
| Chain | Residue |
| A | SER237 |
| A | ASP238 |
| A | ASN239 |
| A | SER259 |
| A | THR307 |
| A | HOH748 |
| A | HOH803 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 408 |
| Chain | Residue |
| A | PHE241 |
| A | GLU247 |
| A | ALA250 |
| A | PRO256 |
| A | GLN257 |
| A | HOH686 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 409 |
| Chain | Residue |
| A | PHE222 |
| A | EPE402 |
| A | EDO406 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 410 |
| Chain | Residue |
| A | PRO118 |
| A | ILE119 |
| A | GLU125 |
| A | HOH571 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 411 |
| Chain | Residue |
| A | ARG321 |
| A | HOH554 |
| A | HOH922 |
| site_id | BC3 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE FMN B 401 |
| Chain | Residue |
| B | GLY24 |
| B | ASN25 |
| B | GLY47 |
| B | ARG48 |
| B | TYR75 |
| B | PRO133 |
| B | PRO134 |
| B | LEU135 |
| B | THR136 |
| B | GLY171 |
| B | GLN213 |
| B | HIS290 |
| B | ASN293 |
| B | ARG342 |
| B | EPE402 |
| B | EDO404 |
| B | HOH513 |
| B | HOH546 |
| B | HOH741 |
| B | HOH842 |
| B | HOH941 |
| site_id | BC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EPE B 402 |
| Chain | Residue |
| B | HOH766 |
| B | TYR75 |
| B | TYR181 |
| B | HIS290 |
| B | ASN293 |
| B | TYR295 |
| B | PHE349 |
| B | FMN401 |
| B | EDO404 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 403 |
| Chain | Residue |
| B | MET138 |
| B | TYR181 |
| B | ASP182 |
| B | ASN183 |
| B | ASN225 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 404 |
| Chain | Residue |
| B | ASN293 |
| B | PHE349 |
| B | FMN401 |
| B | EPE402 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 405 |
| Chain | Residue |
| B | ARG374 |
| B | HOH783 |
| B | HOH957 |
| site_id | BC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO B 406 |
| Chain | Residue |
| B | HOH839 |
| site_id | BC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO B 407 |
| Chain | Residue |
| B | GLU245 |
| site_id | CC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO B 408 |
| Chain | Residue |
| B | HOH905 |
| site_id | CC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO B 409 |
| Chain | Residue |
| B | ASP112 |
| B | HOH656 |
| site_id | CC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO B 410 |
| Chain | Residue |
| B | LEU94 |
| site_id | CC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO B 411 |
| Chain | Residue |
| B | GLU191 |
| site_id | CC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 413 |
| Chain | Residue |
| B | LYS120 |
| B | ASN123 |
| B | GLU125 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"9830020","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11668181","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7881908","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9830019","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11668181","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7881908","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 319 |
| Chain | Residue | Details |
| A | THR136 | electrostatic stabiliser, hydrogen bond donor |
| A | HIS290 | electrostatic stabiliser, hydrogen bond donor |
| A | ASN293 | electrostatic stabiliser, hydrogen bond donor |
| A | TYR295 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | ASN350 | hydrogen bond donor, increase acidity |
| site_id | MCSA2 |
| Number of Residues | 5 |
| Details | M-CSA 319 |
| Chain | Residue | Details |
| B | THR136 | electrostatic stabiliser, hydrogen bond donor |
| B | HIS290 | electrostatic stabiliser, hydrogen bond donor |
| B | ASN293 | electrostatic stabiliser, hydrogen bond donor |
| B | TYR295 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| B | ASN350 | hydrogen bond donor, increase acidity |
