4RLY
Crystal Structure of AnkB Ankyrin Repeats (R1-R9) in Complex with Nav1.2 Ankyrin Binding Domain
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2401 |
| Chain | Residue |
| A | ASN1128 |
| A | ASN2141 |
| A | GLY2174 |
| A | ASN2176 |
| A | GLN2177 |
| A | HOH2521 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2402 |
| Chain | Residue |
| A | ASN2129 |
| A | PHE2131 |
| A | HOH2511 |
| A | HOH2535 |
| A | VAL1121 |
| A | GLY1122 |
| A | LYS2096 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2403 |
| Chain | Residue |
| A | HIS2076 |
| A | HIS2076 |
| A | VAL2077 |
| A | VAL2077 |
| A | GLY2078 |
| A | GLY2078 |
| A | LEU2079 |
| A | LEU2079 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2404 |
| Chain | Residue |
| A | GLY2108 |
| A | GLN2109 |
| A | ALA2110 |
| A | GLU2111 |
| A | HOH2514 |
| A | HOH2574 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2405 |
| Chain | Residue |
| A | ASN2141 |
| A | HIS2142 |
| A | ILE2143 |
| A | ASP2144 |
| A | HOH2558 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2406 |
| Chain | Residue |
| A | LEU2251 |
| A | ASN2254 |
| A | GLY2289 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2407 |
| Chain | Residue |
| A | ASN2278 |
| A | THR2279 |
| A | ASN2280 |
| A | MET2281 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 32 |
| Details | Repeat: {"description":"ANK 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 29 |
| Details | Repeat: {"description":"ANK 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 29 |
| Details | Repeat: {"description":"ANK 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 29 |
| Details | Repeat: {"description":"ANK 4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 29 |
| Details | Repeat: {"description":"ANK 7"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 29 |
| Details | Repeat: {"description":"ANK 8"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q8C8R3","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
