4RLG
The clear crystal structure of pyridoxal-dependent decarboxylase from sphaerobacter thermophilus dsm 20745
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004782 | molecular_function | sulfinoalanine decarboxylase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016830 | molecular_function | carbon-carbon lyase activity |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| A | 0019752 | biological_process | carboxylic acid metabolic process |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0004782 | molecular_function | sulfinoalanine decarboxylase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016830 | molecular_function | carbon-carbon lyase activity |
| B | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0019752 | biological_process | carboxylic acid metabolic process |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| C | 0004782 | molecular_function | sulfinoalanine decarboxylase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0016829 | molecular_function | lyase activity |
| C | 0016830 | molecular_function | carbon-carbon lyase activity |
| C | 0016831 | molecular_function | carboxy-lyase activity |
| C | 0019752 | biological_process | carboxylic acid metabolic process |
| C | 0030170 | molecular_function | pyridoxal phosphate binding |
| D | 0004782 | molecular_function | sulfinoalanine decarboxylase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0016829 | molecular_function | lyase activity |
| D | 0016830 | molecular_function | carbon-carbon lyase activity |
| D | 0016831 | molecular_function | carboxy-lyase activity |
| D | 0019752 | biological_process | carboxylic acid metabolic process |
| D | 0030170 | molecular_function | pyridoxal phosphate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE PMP A 2001 |
| Chain | Residue |
| A | MSE91 |
| A | ALA274 |
| A | ASN301 |
| A | GLN303 |
| A | LLP304 |
| A | HOH2148 |
| A | HOH2186 |
| A | HOH2218 |
| B | THR351 |
| B | HOH634 |
| A | GLY150 |
| A | GLY151 |
| A | SER152 |
| A | ASN155 |
| A | HIS190 |
| A | GLY245 |
| A | THR247 |
| A | ASP272 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 2002 |
| Chain | Residue |
| A | ARG384 |
| A | GLY388 |
| A | GLN391 |
| A | ARG392 |
| A | ASP465 |
| A | PHE468 |
| A | HOH2361 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE K A 2003 |
| Chain | Residue |
| A | VAL389 |
| A | ARG392 |
| A | LEU395 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE PMP B 501 |
| Chain | Residue |
| A | THR351 |
| B | MSE91 |
| B | GLY150 |
| B | GLY151 |
| B | SER152 |
| B | HIS190 |
| B | GLY245 |
| B | THR247 |
| B | ASP272 |
| B | ALA274 |
| B | ASN301 |
| B | GLN303 |
| B | LLP304 |
| B | HOH601 |
| B | HOH680 |
| B | HOH893 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 502 |
| Chain | Residue |
| B | SER115 |
| B | GLU117 |
| B | MSE118 |
| B | HOH754 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 503 |
| Chain | Residue |
| B | ARG384 |
| B | GLU387 |
| B | GLY388 |
| B | ASP465 |
| B | PHE468 |
| B | HOH843 |
| B | HOH901 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE K B 504 |
| Chain | Residue |
| B | VAL389 |
| B | ARG392 |
| B | LEU395 |
| site_id | AC8 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE PMP D 501 |
| Chain | Residue |
| C | THR351 |
| C | HOH611 |
| D | MSE91 |
| D | GLY150 |
| D | GLY151 |
| D | SER152 |
| D | HIS190 |
| D | GLY245 |
| D | THR247 |
| D | ASP272 |
| D | ALA274 |
| D | ASN301 |
| D | GLN303 |
| D | LLP304 |
| D | HOH660 |
| D | HOH869 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ABU D 502 |
| Chain | Residue |
| D | SER186 |
| D | ALA188 |
| D | ALA189 |
| D | HIS190 |
| D | THR191 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ABU D 503 |
| Chain | Residue |
| D | ALA189 |
| D | HIS190 |
| D | THR191 |
| D | LEU193 |
| D | GLN194 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL D 504 |
| Chain | Residue |
| D | ARG384 |
| D | GLU387 |
| D | GLN391 |
| D | ASP465 |
| D | PHE468 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE K D 505 |
| Chain | Residue |
| D | VAL389 |
| D | ARG390 |
| D | ARG392 |
| D | LEU395 |
| site_id | BC4 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE PMP C 501 |
| Chain | Residue |
| C | GLY245 |
| C | THR247 |
| C | ASP272 |
| C | ALA274 |
| C | ASN301 |
| C | GLN303 |
| C | LLP304 |
| C | HOH632 |
| C | HOH683 |
| C | HOH872 |
| D | THR351 |
| C | MSE91 |
| C | GLY150 |
| C | GLY151 |
| C | SER152 |
| C | ASN155 |
| C | HIS190 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL C 502 |
| Chain | Residue |
| C | ARG384 |
| C | GLY388 |
| C | ASP465 |
| C | PHE468 |
| C | HOH810 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE K C 503 |
| Chain | Residue |
| C | VAL389 |
| C | ARG392 |
| C | LEU395 |
