4RL4

Crystal structure of GTP cyclohydrolase II from Helicobacter pylori 26695

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003824	molecular_function	catalytic activity
A	0003935	molecular_function	GTP cyclohydrolase II activity
A	0005525	molecular_function	GTP binding
A	0005829	cellular_component	cytosol
A	0008270	molecular_function	zinc ion binding
A	0009231	biological_process	riboflavin biosynthetic process
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding
B	0000166	molecular_function	nucleotide binding
B	0003824	molecular_function	catalytic activity
B	0003935	molecular_function	GTP cyclohydrolase II activity
B	0005525	molecular_function	GTP binding
B	0005829	cellular_component	cytosol
B	0008270	molecular_function	zinc ion binding
B	0009231	biological_process	riboflavin biosynthetic process
B	0016787	molecular_function	hydrolase activity
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PPV A 201

Chain	Residue
A	ARG50
A	ARG128
A	THR149
A	ASN150
A	ASN151
A	LYS154
A	HOH327

---

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PPV B 201

Chain	Residue
B	THR149
B	ASN150
B	ASN151
B	LYS154
B	LEU169
B	HOH333
B	ARG50
B	ARG128

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00179","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"HAMAP-Rule","id":"MF_00179","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00179","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---