4RKM
Wolinella succinogenes octaheme sulfite reductase MccA, form I
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016002 | molecular_function | sulfite reductase activity |
| A | 0020037 | molecular_function | heme binding |
| A | 0070814 | biological_process | hydrogen sulfide biosynthetic process |
| B | 0016002 | molecular_function | sulfite reductase activity |
| B | 0020037 | molecular_function | heme binding |
| B | 0070814 | biological_process | hydrogen sulfide biosynthetic process |
| C | 0016002 | molecular_function | sulfite reductase activity |
| C | 0020037 | molecular_function | heme binding |
| C | 0070814 | biological_process | hydrogen sulfide biosynthetic process |
| D | 0016002 | molecular_function | sulfite reductase activity |
| D | 0020037 | molecular_function | heme binding |
| D | 0070814 | biological_process | hydrogen sulfide biosynthetic process |
| E | 0016002 | molecular_function | sulfite reductase activity |
| E | 0020037 | molecular_function | heme binding |
| E | 0070814 | biological_process | hydrogen sulfide biosynthetic process |
| F | 0016002 | molecular_function | sulfite reductase activity |
| F | 0020037 | molecular_function | heme binding |
| F | 0070814 | biological_process | hydrogen sulfide biosynthetic process |
| G | 0016002 | molecular_function | sulfite reductase activity |
| G | 0020037 | molecular_function | heme binding |
| G | 0070814 | biological_process | hydrogen sulfide biosynthetic process |
| H | 0016002 | molecular_function | sulfite reductase activity |
| H | 0020037 | molecular_function | heme binding |
| H | 0070814 | biological_process | hydrogen sulfide biosynthetic process |
| I | 0016002 | molecular_function | sulfite reductase activity |
| I | 0020037 | molecular_function | heme binding |
| I | 0070814 | biological_process | hydrogen sulfide biosynthetic process |
| J | 0016002 | molecular_function | sulfite reductase activity |
| J | 0020037 | molecular_function | heme binding |
| J | 0070814 | biological_process | hydrogen sulfide biosynthetic process |
| K | 0016002 | molecular_function | sulfite reductase activity |
| K | 0020037 | molecular_function | heme binding |
| K | 0070814 | biological_process | hydrogen sulfide biosynthetic process |
| L | 0016002 | molecular_function | sulfite reductase activity |
| L | 0020037 | molecular_function | heme binding |
| L | 0070814 | biological_process | hydrogen sulfide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CU1 A 801 |
| Chain | Residue |
| A | CYS399 |
| A | CYS495 |
| A | SX802 |
| A | HEM807 |
| A | SO2814 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SX A 802 |
| Chain | Residue |
| A | CU1801 |
| A | HEM807 |
| A | SO2814 |
| A | HOH1233 |
| A | TYR301 |
| A | ARG366 |
| A | LYS393 |
| A | CYS399 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE BU3 A 803 |
| Chain | Residue |
| A | ILE357 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE BU3 A 804 |
| Chain | Residue |
| A | LYS288 |
| A | SER394 |
| A | ARG539 |
| A | ASP540 |
| A | HOH1284 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 805 |
| Chain | Residue |
| A | ASN359 |
| A | GLN365 |
| A | GLY403 |
| A | THR406 |
| A | TYR412 |
| A | HOH1249 |
| site_id | AC6 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE HEM A 806 |
| Chain | Residue |
| A | CYS143 |
| A | CYS146 |
| A | HIS147 |
| A | GLU340 |
| A | HIS343 |
| A | GLY346 |
| A | GLY347 |
| A | HIS348 |
| A | HEM808 |
| A | HOH990 |
| B | ARG124 |
| B | VAL125 |
| B | LEU356 |
| B | ILE357 |
| B | SER358 |
| B | ASN359 |
| B | CYS360 |
| B | GLU361 |
| B | ARG362 |
| B | HOH914 |
| B | HOH1030 |
| site_id | AC7 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE HEM A 807 |
| Chain | Residue |
| A | TYR123 |
| A | VAL202 |
| A | GLY203 |
| A | HIS204 |
| A | ARG206 |
| A | THR207 |
| A | LYS208 |
| A | PHE212 |
| A | ARG218 |
| A | TYR301 |
| A | CYS302 |
| A | CYS305 |
| A | HIS306 |
| A | CYS363 |
| A | HIS364 |
| A | CYS399 |
| A | GLY400 |
| A | GLU402 |
| A | ARG513 |
| A | CU1801 |
| A | SX802 |
| A | HEM809 |
| A | HEM810 |
| A | SO2814 |
| site_id | AC8 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE HEM A 808 |
| Chain | Residue |
| A | HIS147 |
| A | GLN150 |
| A | TYR151 |
| A | TRP154 |
| A | HIS159 |
| A | VAL337 |
| A | SER338 |
| A | CYS339 |
| A | CYS342 |
| A | HIS343 |
| A | ILE357 |
| A | SER358 |
| A | ALA419 |
| A | PRO424 |
| A | HIS425 |
| A | LYS459 |
| A | HEM806 |
| A | HEM809 |
| A | HOH960 |
| A | HOH1000 |
| A | HOH1208 |
| A | HOH1234 |
| B | ASN359 |
| B | GLU361 |
| B | ARG417 |
| B | HOH958 |
| site_id | AC9 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE HEM A 809 |
| Chain | Residue |
| A | HIS204 |
| A | VAL304 |
| A | CYS305 |
| A | HIS306 |
| A | VAL337 |
| A | CYS360 |
| A | ARG362 |
| A | CYS363 |
| A | HIS364 |
| A | VAL427 |
| A | THR428 |
| A | SER454 |
| A | ARG513 |
| A | HEM807 |
| A | HEM808 |
| A | HEM810 |
| A | ARG158 |
| A | HIS159 |
| A | THR162 |
| site_id | BC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE HEM A 810 |
| Chain | Residue |
| A | ARG206 |
| A | HIS364 |
| A | GLU402 |
| A | GLY403 |
| A | MET416 |
| A | ARG417 |
| A | CYS418 |
| A | CYS421 |
| A | HIS422 |
| A | SER454 |
| A | LYS455 |
| A | PRO456 |
| A | LEU458 |
| A | PHE491 |
| A | ARG513 |
| A | ARG514 |
| A | HIS516 |
| A | TRP518 |
| A | HEM807 |
| A | HEM809 |
| A | HOH920 |
| A | HOH1087 |
| A | HOH1206 |
| A | HOH1316 |
| site_id | BC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE HEM A 811 |
| Chain | Residue |
| A | HIS411 |
| A | MET416 |
| A | LYS460 |
| A | CYS462 |
| A | CYS465 |
| A | HIS466 |
| A | HIS488 |
| A | TRP518 |
| A | ARG553 |
| A | HEM812 |
| A | HOH928 |
| A | HOH935 |
| A | HOH955 |
| A | HOH994 |
| A | HOH1181 |
| site_id | BC3 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE HEM A 812 |
| Chain | Residue |
| A | CYS462 |
| A | HIS466 |
| A | GLN469 |
| A | GLN473 |
| A | HIS479 |
| A | CYS484 |
| A | CYS487 |
| A | HIS488 |
| A | ILE520 |
| A | VAL522 |
| A | GLN606 |
| A | ASP657 |
| A | GLY658 |
| A | HIS663 |
| A | HEM811 |
| A | HOH974 |
| A | HOH977 |
| A | HOH1053 |
| A | HOH1139 |
| A | HOH1180 |
| A | HOH1189 |
| A | HOH1217 |
| site_id | BC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE HEM A 813 |
| Chain | Residue |
| A | THR478 |
| A | HIS479 |
| A | SER486 |
| A | ALA561 |
| A | CYS562 |
| A | ALA575 |
| A | CYS578 |
| A | HIS579 |
| A | LEU586 |
| A | VAL602 |
| A | TRP605 |
| F | HEM814 |
| site_id | BC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SO2 A 814 |
| Chain | Residue |
| A | LYS208 |
| A | TYR285 |
| A | ARG366 |
| A | LYS393 |
| A | CYS399 |
| A | CYS495 |
| A | CU1801 |
| A | SX802 |
| A | HEM807 |
| A | HOH1232 |
| A | HOH1233 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CU1 B 801 |
| Chain | Residue |
| B | CYS399 |
| B | CYS495 |
| B | SX802 |
| B | HEM808 |
| site_id | BC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SX B 802 |
| Chain | Residue |
| B | ARG366 |
| B | LYS393 |
| B | CYS399 |
| B | CU1801 |
| B | HEM808 |
| B | HOH1148 |
| B | HOH1182 |
| site_id | BC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BU3 B 803 |
| Chain | Residue |
| A | HOH1000 |
| B | ILE357 |
| site_id | BC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BU3 B 804 |
| Chain | Residue |
| B | LYS288 |
| B | SER394 |
| B | ASP540 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE BU3 B 805 |
| Chain | Residue |
| B | GLN615 |
| B | GLY619 |
| B | GLN683 |
| I | GLN615 |
| I | VAL618 |
| I | GLN683 |
| site_id | CC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT B 806 |
| Chain | Residue |
| B | ASN359 |
| B | GLN365 |
| B | GLY403 |
| B | THR406 |
| B | TYR412 |
| B | HOH1158 |
| site_id | CC3 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE HEM B 807 |
| Chain | Residue |
| B | CYS143 |
| B | CYS146 |
| B | HIS147 |
| B | GLU340 |
| B | HIS343 |
| B | GLY347 |
| B | HIS348 |
| B | HEM809 |
| B | HOH923 |
| B | HOH973 |
| C | ARG124 |
| C | VAL125 |
| C | ILE357 |
| C | SER358 |
| C | ASN359 |
| C | CYS360 |
| C | GLU361 |
| C | ARG362 |
| C | HOH1123 |
| site_id | CC4 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM B 808 |
| Chain | Residue |
| B | TYR123 |
| B | VAL202 |
| B | GLY203 |
| B | HIS204 |
| B | ARG206 |
| B | THR207 |
| B | LYS208 |
| B | ARG218 |
| B | TYR301 |
| B | CYS302 |
| B | CYS305 |
| B | HIS306 |
| B | CYS363 |
| B | HIS364 |
| B | CYS399 |
| B | GLY400 |
| B | GLU402 |
| B | CYS495 |
| B | ARG513 |
| B | CU1801 |
| B | SX802 |
| B | HEM810 |
| B | HEM811 |
| site_id | CC5 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM B 809 |
| Chain | Residue |
| B | CYS143 |
| B | HIS147 |
| B | TYR151 |
| B | TRP154 |
| B | HIS159 |
| B | VAL337 |
| B | CYS339 |
| B | CYS342 |
| B | HIS343 |
| B | SER358 |
| B | ALA419 |
| B | PRO424 |
| B | HIS425 |
| B | LYS459 |
| B | HEM807 |
| B | HEM810 |
| B | HOH908 |
| B | HOH976 |
| B | HOH992 |
| B | HOH1193 |
| C | ASN359 |
| C | GLU361 |
| C | ARG417 |
| site_id | CC6 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE HEM B 810 |
| Chain | Residue |
| B | ARG158 |
| B | HIS159 |
| B | THR162 |
| B | HIS204 |
| B | VAL304 |
| B | CYS305 |
| B | HIS306 |
| B | VAL337 |
| B | SER358 |
| B | CYS360 |
| B | ARG362 |
| B | CYS363 |
| B | HIS364 |
| B | VAL427 |
| B | THR428 |
| B | SER454 |
| B | ARG513 |
| B | HEM808 |
| B | HEM809 |
| B | HEM811 |
| site_id | CC7 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE HEM B 811 |
| Chain | Residue |
| B | ARG206 |
| B | HIS364 |
| B | GLU402 |
| B | GLY403 |
| B | MET416 |
| B | CYS418 |
| B | CYS421 |
| B | HIS422 |
| B | SER454 |
| B | LYS455 |
| B | LEU458 |
| B | PHE491 |
| B | ARG513 |
| B | ARG514 |
| B | HIS516 |
| B | HEM808 |
| B | HEM810 |
| B | HEM812 |
| B | HOH948 |
| B | HOH959 |
| B | HOH1087 |
| B | HOH1128 |
| site_id | CC8 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE HEM B 812 |
| Chain | Residue |
| B | HIS411 |
| B | MET416 |
| B | LYS460 |
| B | CYS462 |
| B | CYS465 |
| B | HIS466 |
| B | HIS488 |
| B | MET489 |
| B | TRP518 |
| B | ARG553 |
| B | HEM811 |
| B | HEM813 |
| B | HOH921 |
| B | HOH1035 |
| B | HOH1142 |
| site_id | CC9 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE HEM B 813 |
| Chain | Residue |
| B | CYS462 |
| B | HIS466 |
| B | GLN469 |
| B | HIS479 |
| B | CYS484 |
| B | CYS487 |
| B | HIS488 |
| B | VAL522 |
| B | GLN606 |
| B | ASP657 |
| B | HIS663 |
| B | HEM812 |
| B | HOH917 |
| B | HOH987 |
| B | HOH990 |
| B | HOH1002 |
| B | HOH1080 |
| B | HOH1091 |
| site_id | DC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE HEM B 814 |
| Chain | Residue |
| B | THR478 |
| B | HIS479 |
| B | ASN482 |
| B | SER486 |
| B | ALA561 |
| B | CYS562 |
| B | ALA575 |
| B | CYS578 |
| B | HIS579 |
| B | GLU601 |
| B | VAL602 |
| B | HOH1027 |
| site_id | DC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CU1 C 801 |
| Chain | Residue |
| C | CYS399 |
| C | CYS495 |
| C | SX802 |
| C | HEM807 |
| site_id | DC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SX C 802 |
| Chain | Residue |
| C | ARG366 |
| C | LYS393 |
| C | CYS399 |
| C | CU1801 |
| C | HEM807 |
| C | HOH1127 |
| C | HOH1128 |
| site_id | DC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BU3 C 803 |
| Chain | Residue |
| B | HOH976 |
| C | ILE357 |
| site_id | DC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE BU3 C 804 |
| Chain | Residue |
| C | LYS288 |
| C | SER394 |
| C | TYR499 |
| C | ASP540 |
| C | HOH924 |
| site_id | DC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT C 805 |
| Chain | Residue |
| C | GLN365 |
| C | GLY403 |
| C | THR406 |
| C | TYR412 |
| C | HOH1035 |
| site_id | DC7 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE HEM C 806 |
| Chain | Residue |
| A | ARG124 |
| A | VAL125 |
| A | ALA126 |
| A | ILE357 |
| A | SER358 |
| A | ASN359 |
| A | CYS360 |
| A | GLU361 |
| A | ARG362 |
| A | HOH958 |
| C | CYS143 |
| C | CYS146 |
| C | HIS147 |
| C | GLU340 |
| C | HIS343 |
| C | GLY346 |
| C | GLY347 |
| C | HIS348 |
| C | LEU349 |
| C | HEM808 |
| C | HOH907 |
| C | HOH916 |
| site_id | DC8 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE HEM C 807 |
| Chain | Residue |
| C | TYR123 |
| C | VAL202 |
| C | GLY203 |
| C | HIS204 |
| C | ARG206 |
| C | THR207 |
| C | LYS208 |
| C | ARG218 |
| C | TYR301 |
| C | CYS302 |
| C | CYS305 |
| C | HIS306 |
| C | CYS363 |
| C | HIS364 |
| C | CYS399 |
| C | GLY400 |
| C | GLU402 |
| C | ARG513 |
| C | CU1801 |
| C | SX802 |
| C | HEM809 |
| C | HEM810 |
| site_id | DC9 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE HEM C 808 |
| Chain | Residue |
| A | ASN359 |
| A | GLU361 |
| A | ARG417 |
| A | HOH903 |
| C | HIS147 |
| C | TYR151 |
| C | TRP154 |
| C | HIS159 |
| C | VAL337 |
| C | SER338 |
| C | CYS339 |
| C | CYS342 |
| C | HIS343 |
| C | ILE357 |
| C | SER358 |
| C | ALA419 |
| C | PRO424 |
| C | HIS425 |
| C | LYS459 |
| C | HEM806 |
| C | HEM809 |
| C | HOH1009 |
| C | HOH1046 |
| C | HOH1068 |
| C | HOH1071 |
| C | HOH1109 |
| site_id | EC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE HEM C 809 |
| Chain | Residue |
| C | ARG158 |
| C | HIS159 |
| C | THR162 |
| C | HIS204 |
| C | VAL304 |
| C | CYS305 |
| C | HIS306 |
| C | VAL337 |
| C | SER358 |
| C | CYS360 |
| C | CYS363 |
| C | HIS364 |
| C | VAL427 |
| C | THR428 |
| C | SER454 |
| C | ARG513 |
| C | HEM807 |
| C | HEM808 |
| C | HEM810 |
| site_id | EC2 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE HEM C 810 |
| Chain | Residue |
| C | ARG206 |
| C | HIS364 |
| C | GLU402 |
| C | GLY403 |
| C | MET416 |
| C | CYS418 |
| C | CYS421 |
| C | HIS422 |
| C | SER454 |
| C | LYS455 |
| C | PRO456 |
| C | LEU458 |
| C | MET489 |
| C | PHE491 |
| C | ARG513 |
| C | ARG514 |
| C | HIS516 |
| C | TRP518 |
| C | HEM807 |
| C | HEM809 |
| C | HEM811 |
| C | HOH908 |
| C | HOH1000 |
| C | HOH1013 |
| C | HOH1026 |
| C | HOH1074 |
| site_id | EC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE HEM C 811 |
| Chain | Residue |
| C | HIS411 |
| C | MET416 |
| C | LYS460 |
| C | CYS462 |
| C | CYS465 |
| C | HIS466 |
| C | HIS488 |
| C | TRP518 |
| C | ARG553 |
| C | HEM810 |
| C | HEM812 |
| C | HOH989 |
| C | HOH1086 |
| site_id | EC4 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE HEM C 812 |
| Chain | Residue |
| C | CYS462 |
| C | THR463 |
| C | HIS466 |
| C | GLN469 |
| C | HIS479 |
| C | CYS484 |
| C | CYS487 |
| C | HIS488 |
| C | ILE520 |
| C | GLN606 |
| C | ASP657 |
| C | GLY658 |
| C | HIS663 |
| C | HEM811 |
| C | HOH947 |
| C | HOH998 |
| C | HOH1006 |
| C | HOH1010 |
| site_id | EC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE HEM C 813 |
| Chain | Residue |
| C | THR478 |
| C | HIS479 |
| C | SER486 |
| C | ALA561 |
| C | CYS562 |
| C | ALA575 |
| C | CYS578 |
| C | HIS579 |
| C | VAL602 |
| site_id | EC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CU1 D 801 |
| Chain | Residue |
| D | CYS399 |
| D | CYS495 |
| D | SO2802 |
| D | HEM807 |
| site_id | EC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO2 D 802 |
| Chain | Residue |
| D | LYS208 |
| D | TYR285 |
| D | ARG366 |
| D | LYS393 |
| D | CYS399 |
| D | CU1801 |
| D | HEM807 |
| D | HOH1186 |
| site_id | EC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE BU3 D 803 |
| Chain | Residue |
| D | ILE357 |
| D | ASN359 |
| E | HEM806 |
| E | HEM808 |
| E | HOH952 |
| site_id | EC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE BU3 D 804 |
| Chain | Residue |
| D | LYS288 |
| D | SER394 |
| D | ASP540 |
| D | HOH1077 |
| site_id | FC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT D 805 |
| Chain | Residue |
| D | ASN359 |
| D | GLN365 |
| D | GLY403 |
| D | THR406 |
| D | TYR412 |
| D | HOH949 |
| site_id | FC2 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM D 806 |
| Chain | Residue |
| D | CYS143 |
| D | CYS146 |
| D | HIS147 |
| D | GLU340 |
| D | HIS343 |
| D | GLY346 |
| D | GLY347 |
| D | HIS348 |
| D | LEU349 |
| D | HEM808 |
| D | HOH971 |
| D | HOH1076 |
| K | ARG124 |
| K | VAL125 |
| K | ALA126 |
| K | ILE357 |
| K | SER358 |
| K | ASN359 |
| K | CYS360 |
| K | GLU361 |
| K | ARG362 |
| K | BU3803 |
| K | HOH980 |
| site_id | FC3 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM D 807 |
| Chain | Residue |
| D | TYR123 |
| D | VAL202 |
| D | GLY203 |
| D | HIS204 |
| D | ARG206 |
| D | THR207 |
| D | LYS208 |
| D | ARG218 |
| D | TYR301 |
| D | CYS302 |
| D | CYS305 |
| D | HIS306 |
| D | CYS363 |
| D | HIS364 |
| D | CYS399 |
| D | GLY400 |
| D | GLU402 |
| D | CYS495 |
| D | ARG513 |
| D | CU1801 |
| D | SO2802 |
| D | HEM809 |
| D | HEM810 |
| site_id | FC4 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE HEM D 808 |
| Chain | Residue |
| D | HIS147 |
| D | GLN150 |
| D | TYR151 |
| D | TRP154 |
| D | HIS159 |
| D | VAL337 |
| D | SER338 |
| D | CYS339 |
| D | CYS342 |
| D | HIS343 |
| D | ILE357 |
| D | SER358 |
| D | ALA419 |
| D | PRO424 |
| D | HIS425 |
| D | LYS459 |
| D | HEM806 |
| D | HEM809 |
| D | HOH913 |
| D | HOH952 |
| D | HOH980 |
| K | ASN359 |
| K | GLU361 |
| K | ARG417 |
| K | HOH959 |
| site_id | FC5 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE HEM D 809 |
| Chain | Residue |
| D | ARG158 |
| D | HIS159 |
| D | THR162 |
| D | HIS204 |
| D | VAL304 |
| D | CYS305 |
| D | HIS306 |
| D | VAL337 |
| D | CYS360 |
| D | CYS363 |
| D | HIS364 |
| D | VAL427 |
| D | THR428 |
| D | SER454 |
| D | ARG513 |
| D | HEM807 |
| D | HEM808 |
| D | HEM810 |
| site_id | FC6 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM D 810 |
| Chain | Residue |
| D | ARG206 |
| D | HIS364 |
| D | GLU402 |
| D | GLY403 |
| D | MET416 |
| D | ARG417 |
| D | CYS418 |
| D | CYS421 |
| D | HIS422 |
| D | SER454 |
| D | LYS455 |
| D | PRO456 |
| D | LEU458 |
| D | PHE491 |
| D | ARG513 |
| D | ARG514 |
| D | HIS516 |
| D | HEM807 |
| D | HEM809 |
| D | HOH953 |
| D | HOH976 |
| D | HOH1039 |
| D | HOH1151 |
| site_id | FC7 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE HEM D 811 |
| Chain | Residue |
| D | HIS411 |
| D | MET416 |
| D | LYS460 |
| D | CYS462 |
| D | CYS465 |
| D | HIS466 |
| D | HIS488 |
| D | TRP518 |
| D | ARG553 |
| D | HEM812 |
| D | HOH954 |
| D | HOH1004 |
| D | HOH1059 |
| D | HOH1116 |
| D | HOH1117 |
| E | ASP464 |
| site_id | FC8 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE HEM D 812 |
| Chain | Residue |
| D | CYS462 |
| D | HIS466 |
| D | GLN473 |
| D | HIS479 |
| D | CYS484 |
| D | CYS487 |
| D | HIS488 |
| D | ILE520 |
| D | GLN606 |
| D | ASP657 |
| D | GLY658 |
| D | HIS663 |
| D | HEM811 |
| D | HOH906 |
| D | HOH915 |
| D | HOH931 |
| D | HOH1057 |
| D | HOH1184 |
| site_id | FC9 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE HEM D 813 |
| Chain | Residue |
| D | THR478 |
| D | HIS479 |
| D | SER486 |
| D | CYS562 |
| D | ALA575 |
| D | CYS578 |
| D | HIS579 |
| D | LEU586 |
| D | LEU590 |
| D | VAL602 |
| D | TRP605 |
| H | HEM814 |
| site_id | GC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CU1 E 801 |
| Chain | Residue |
| E | CYS399 |
| E | CYS495 |
| E | SX802 |
| E | HEM807 |
| site_id | GC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SX E 802 |
| Chain | Residue |
| E | ARG366 |
| E | LYS393 |
| E | CYS399 |
| E | CU1801 |
| E | HEM807 |
| site_id | GC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE BU3 E 803 |
| Chain | Residue |
| E | ILE357 |
| E | ASN359 |
| E | HOH1058 |
| K | ILE357 |
| site_id | GC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE BU3 E 804 |
| Chain | Residue |
| E | LYS288 |
| E | SER394 |
| E | TYR499 |
| E | ASP540 |
| E | HOH1018 |
| E | HOH1110 |
| site_id | GC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT E 805 |
| Chain | Residue |
| E | GLN365 |
| E | GLY403 |
| E | THR406 |
| E | TYR412 |
| E | HOH1105 |
| site_id | GC6 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM E 806 |
| Chain | Residue |
| D | ARG124 |
| D | VAL125 |
| D | ALA126 |
| D | ILE357 |
| D | SER358 |
| D | ASN359 |
| D | CYS360 |
| D | GLU361 |
| D | ARG362 |
| D | BU3803 |
| D | HOH908 |
| D | HOH966 |
| E | CYS143 |
| E | CYS146 |
| E | HIS147 |
| E | GLU340 |
| E | HIS343 |
| E | GLY346 |
| E | GLY347 |
| E | HIS348 |
| E | LEU349 |
| E | HEM808 |
| E | HOH907 |
| site_id | GC7 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM E 807 |
| Chain | Residue |
| E | TYR123 |
| E | ARG158 |
| E | VAL202 |
| E | GLY203 |
| E | HIS204 |
| E | ARG206 |
| E | THR207 |
| E | LYS208 |
| E | ARG218 |
| E | TYR301 |
| E | CYS302 |
| E | CYS305 |
| E | HIS306 |
| E | CYS363 |
| E | HIS364 |
| E | CYS399 |
| E | GLY400 |
| E | GLU402 |
| E | ARG513 |
| E | CU1801 |
| E | SX802 |
| E | HEM809 |
| E | HEM810 |
| site_id | GC8 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE HEM E 808 |
| Chain | Residue |
| D | ASN359 |
| D | GLU361 |
| D | ARG417 |
| D | BU3803 |
| D | HOH967 |
| E | CYS143 |
| E | HIS147 |
| E | TYR151 |
| E | TRP154 |
| E | HIS159 |
| E | VAL337 |
| E | CYS339 |
| E | CYS342 |
| E | HIS343 |
| E | ILE357 |
| E | SER358 |
| E | ALA419 |
| E | PRO424 |
| E | HIS425 |
| E | LYS459 |
| E | HEM806 |
| E | HEM809 |
| E | HOH924 |
| E | HOH952 |
| E | HOH966 |
| site_id | GC9 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE HEM E 809 |
| Chain | Residue |
| E | ARG158 |
| E | HIS159 |
| E | THR162 |
| E | HIS204 |
| E | VAL304 |
| E | CYS305 |
| E | HIS306 |
| E | VAL337 |
| E | SER358 |
| E | CYS360 |
| E | CYS363 |
| E | HIS364 |
| E | VAL427 |
| E | THR428 |
| E | SER454 |
| E | ARG513 |
| E | HEM807 |
| E | HEM808 |
| E | HEM810 |
| site_id | HC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM E 810 |
| Chain | Residue |
| E | ARG206 |
| E | HIS364 |
| E | GLU402 |
| E | GLY403 |
| E | MET416 |
| E | ARG417 |
| E | CYS418 |
| E | CYS421 |
| E | HIS422 |
| E | SER454 |
| E | LYS455 |
| E | LEU458 |
| E | PHE491 |
| E | ARG513 |
| E | ARG514 |
| E | HIS516 |
| E | TRP518 |
| E | HEM807 |
| E | HEM809 |
| E | HEM811 |
| E | HOH929 |
| E | HOH976 |
| E | HOH1115 |
| site_id | HC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE HEM E 811 |
| Chain | Residue |
| E | HIS411 |
| E | MET416 |
| E | LYS460 |
| E | CYS462 |
| E | CYS465 |
| E | HIS466 |
| E | HIS488 |
| E | MET489 |
| E | TRP518 |
| E | ARG553 |
| E | HEM810 |
| E | HEM812 |
| E | HOH927 |
| E | HOH950 |
| site_id | HC3 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE HEM E 812 |
| Chain | Residue |
| E | CYS462 |
| E | HIS466 |
| E | GLN469 |
| E | HIS479 |
| E | CYS484 |
| E | CYS487 |
| E | HIS488 |
| E | ILE520 |
| E | VAL522 |
| E | GLN606 |
| E | ASP657 |
| E | GLY658 |
| E | HIS663 |
| E | HEM811 |
| E | HOH903 |
| E | HOH937 |
| E | HOH999 |
| E | HOH1004 |
| site_id | HC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE HEM E 813 |
| Chain | Residue |
| E | THR478 |
| E | HIS479 |
| E | ASN482 |
| E | SER486 |
| E | ALA561 |
| E | CYS562 |
| E | ALA575 |
| E | CYS578 |
| E | HIS579 |
| E | VAL602 |
| E | TRP605 |
| site_id | HC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CU1 F 801 |
| Chain | Residue |
| F | CYS399 |
| F | CYS495 |
| F | SX802 |
| F | HEM808 |
| site_id | HC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SX F 802 |
| Chain | Residue |
| F | TYR285 |
| F | ARG366 |
| F | LYS393 |
| F | CYS399 |
| F | CU1801 |
| F | HEM808 |
| F | HOH1086 |
| site_id | HC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE BU3 F 803 |
| Chain | Residue |
| F | ILE357 |
| J | HEM806 |
| J | HEM808 |
| J | HOH929 |
| site_id | HC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BU3 F 804 |
| Chain | Residue |
| F | LYS288 |
| F | SER394 |
| F | ASP540 |
| site_id | HC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE BU3 F 805 |
| Chain | Residue |
| F | THR420 |
| site_id | IC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT F 806 |
| Chain | Residue |
| F | ASN359 |
| F | GLN365 |
| F | GLY403 |
| F | TYR412 |
| F | HOH1145 |
| site_id | IC2 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE HEM F 807 |
| Chain | Residue |
| F | CYS143 |
| F | CYS146 |
| F | HIS147 |
| F | CYS339 |
| F | GLU340 |
| F | HIS343 |
| F | HIS348 |
| F | HEM809 |
| F | HOH928 |
| I | ARG124 |
| I | VAL125 |
| I | ALA126 |
| I | ILE357 |
| I | SER358 |
| I | ASN359 |
| I | CYS360 |
| I | GLU361 |
| I | ARG362 |
| I | HOH915 |
| I | HOH967 |
| site_id | IC3 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM F 808 |
| Chain | Residue |
| F | TYR123 |
| F | ARG158 |
| F | VAL202 |
| F | GLY203 |
| F | HIS204 |
| F | ARG206 |
| F | THR207 |
| F | LYS208 |
| F | ARG218 |
| F | TYR301 |
| F | CYS302 |
| F | CYS305 |
| F | HIS306 |
| F | CYS363 |
| F | HIS364 |
| F | CYS399 |
| F | GLY400 |
| F | GLU402 |
| F | ARG513 |
| F | CU1801 |
| F | SX802 |
| F | HEM810 |
| F | HEM811 |
| site_id | IC4 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE HEM F 809 |
| Chain | Residue |
| F | PRO424 |
| F | HIS425 |
| F | LYS459 |
| F | HEM807 |
| F | HEM810 |
| F | HOH1033 |
| F | HOH1064 |
| F | HOH1096 |
| F | HOH1097 |
| I | ASN359 |
| I | GLU361 |
| I | ARG417 |
| F | HIS147 |
| F | TYR151 |
| F | TRP154 |
| F | HIS159 |
| F | VAL337 |
| F | CYS339 |
| F | CYS342 |
| F | HIS343 |
| F | SER358 |
| F | ALA419 |
| site_id | IC5 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE HEM F 810 |
| Chain | Residue |
| F | ARG158 |
| F | HIS159 |
| F | THR162 |
| F | HIS204 |
| F | VAL304 |
| F | CYS305 |
| F | HIS306 |
| F | VAL337 |
| F | CYS360 |
| F | CYS363 |
| F | HIS364 |
| F | VAL427 |
| F | THR428 |
| F | SER454 |
| F | ARG513 |
| F | HEM808 |
| F | HEM809 |
| F | HEM811 |
| site_id | IC6 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE HEM F 811 |
| Chain | Residue |
| F | ARG206 |
| F | HIS364 |
| F | GLU402 |
| F | GLY403 |
| F | HIS411 |
| F | MET416 |
| F | ARG417 |
| F | CYS418 |
| F | CYS421 |
| F | HIS422 |
| F | SER454 |
| F | LYS455 |
| F | PRO456 |
| F | LEU458 |
| F | PHE491 |
| F | ARG513 |
| F | ARG514 |
| F | HIS516 |
| F | TRP518 |
| F | HEM808 |
| F | HEM810 |
| F | HOH903 |
| F | HOH940 |
| F | HOH972 |
| F | HOH1008 |
| site_id | IC7 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE HEM F 812 |
| Chain | Residue |
| F | HIS411 |
| F | LYS414 |
| F | MET416 |
| F | LYS460 |
| F | CYS462 |
| F | CYS465 |
| F | HIS466 |
| F | HIS488 |
| F | TRP518 |
| F | ARG553 |
| F | HEM813 |
| F | HOH929 |
| F | HOH955 |
| F | HOH1000 |
| site_id | IC8 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE HEM F 813 |
| Chain | Residue |
| F | CYS462 |
| F | HIS466 |
| F | GLN469 |
| F | GLN473 |
| F | HIS479 |
| F | CYS484 |
| F | CYS487 |
| F | HIS488 |
| F | ILE520 |
| F | GLN606 |
| F | ASP657 |
| F | HIS663 |
| F | HEM812 |
| F | HOH901 |
| F | HOH902 |
| F | HOH946 |
| F | HOH949 |
| F | HOH976 |
| F | HOH994 |
| site_id | IC9 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE HEM F 814 |
| Chain | Residue |
| A | HEM813 |
| F | THR478 |
| F | HIS479 |
| F | SER486 |
| F | CYS487 |
| F | CYS562 |
| F | CYS578 |
| F | HIS579 |
| F | LEU586 |
| F | LEU590 |
| F | GLU601 |
| F | VAL602 |
| F | TRP605 |
| F | HOH909 |
| site_id | JC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CU1 H 801 |
| Chain | Residue |
| H | CYS399 |
| H | CYS495 |
| H | SX802 |
| H | HEM808 |
| site_id | JC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SX H 802 |
| Chain | Residue |
| H | ARG366 |
| H | LYS393 |
| H | CYS399 |
| H | CU1801 |
| H | HEM808 |
| H | HOH1075 |
| H | HOH1082 |
| site_id | JC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BU3 H 803 |
| Chain | Residue |
| G | ILE357 |
| H | ILE357 |
| site_id | JC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BU3 H 804 |
| Chain | Residue |
| H | LYS288 |
| H | SER394 |
| H | ASP540 |
| site_id | JC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE BU3 H 805 |
| Chain | Residue |
| G | LYS475 |
| G | HOH1015 |
| H | TYR624 |
| H | TYR641 |
| H | GLN648 |
| H | HOH1148 |
| site_id | JC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT H 806 |
| Chain | Residue |
| H | ASN359 |
| H | GLN365 |
| H | GLY403 |
| H | THR406 |
| H | TYR412 |
| site_id | JC7 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE HEM H 807 |
| Chain | Residue |
| H | CYS143 |
| H | CYS146 |
| H | HIS147 |
| H | GLU340 |
| H | HIS343 |
| H | GLY346 |
| H | GLY347 |
| H | HIS348 |
| H | LEU349 |
| H | HEM809 |
| H | HOH915 |
| L | ARG124 |
| L | VAL125 |
| L | ILE357 |
| L | SER358 |
| L | ASN359 |
| L | CYS360 |
| L | GLU361 |
| L | ARG362 |
| L | HOH921 |
| L | HOH945 |
| site_id | JC8 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE HEM H 808 |
| Chain | Residue |
| H | TYR123 |
| H | VAL202 |
| H | GLY203 |
| H | HIS204 |
| H | ARG206 |
| H | THR207 |
| H | LYS208 |
| H | ARG218 |
| H | TYR301 |
| H | CYS302 |
| H | CYS305 |
| H | HIS306 |
| H | CYS363 |
| H | HIS364 |
| H | CYS399 |
| H | GLY400 |
| H | GLU402 |
| H | ARG513 |
| H | CU1801 |
| H | SX802 |
| H | HEM810 |
| H | HEM811 |
| site_id | JC9 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE HEM H 809 |
| Chain | Residue |
| H | HIS147 |
| H | TYR151 |
| H | TRP154 |
| H | HIS159 |
| H | VAL337 |
| H | CYS339 |
| H | CYS342 |
| H | HIS343 |
| H | SER358 |
| H | ALA419 |
| H | PRO424 |
| H | HIS425 |
| H | LYS459 |
| H | HEM807 |
| H | HEM810 |
| H | HOH925 |
| H | HOH1125 |
| L | ASN359 |
| L | ARG417 |
| L | HOH911 |
| site_id | KC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE HEM H 810 |
| Chain | Residue |
| H | ARG158 |
| H | HIS159 |
| H | THR162 |
| H | HIS204 |
| H | VAL304 |
| H | CYS305 |
| H | HIS306 |
| H | VAL337 |
| H | CYS360 |
| H | ARG362 |
| H | CYS363 |
| H | HIS364 |
| H | VAL427 |
| H | THR428 |
| H | SER454 |
| H | ARG513 |
| H | HEM808 |
| H | HEM809 |
| H | HEM811 |
| site_id | KC2 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE HEM H 811 |
| Chain | Residue |
| H | ARG206 |
| H | HIS364 |
| H | GLU402 |
| H | GLY403 |
| H | MET416 |
| H | ARG417 |
| H | CYS418 |
| H | CYS421 |
| H | HIS422 |
| H | SER454 |
| H | LYS455 |
| H | PRO456 |
| H | LEU458 |
| H | PHE491 |
| H | ARG513 |
| H | ARG514 |
| H | HIS516 |
| H | TRP518 |
| H | HEM808 |
| H | HEM810 |
| H | HOH910 |
| H | HOH996 |
| H | HOH1061 |
| H | HOH1073 |
| site_id | KC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE HEM H 812 |
| Chain | Residue |
| H | HIS411 |
| H | MET416 |
| H | LYS460 |
| H | CYS462 |
| H | CYS465 |
| H | HIS466 |
| H | HIS488 |
| H | TRP518 |
| H | ARG553 |
| H | HEM813 |
| H | HOH916 |
| H | HOH923 |
| H | HOH1054 |
| H | HOH1137 |
| site_id | KC4 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE HEM H 813 |
| Chain | Residue |
| H | CYS462 |
| H | THR463 |
| H | HIS466 |
| H | GLN473 |
| H | HIS479 |
| H | CYS484 |
| H | CYS487 |
| H | HIS488 |
| H | ILE520 |
| H | VAL522 |
| H | GLN606 |
| H | ASP657 |
| H | GLY658 |
| H | HIS663 |
| H | HEM812 |
| H | HOH908 |
| H | HOH988 |
| H | HOH1004 |
| H | HOH1028 |
| H | HOH1029 |
| H | HOH1077 |
| site_id | KC5 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE HEM H 814 |
| Chain | Residue |
| D | HEM813 |
| H | THR478 |
| H | HIS479 |
| H | SER486 |
| H | CYS562 |
| H | ALA575 |
| H | CYS578 |
| H | HIS579 |
| H | LEU586 |
| H | LEU590 |
| H | PHE592 |
| H | VAL602 |
| H | TRP605 |
| H | HOH1079 |
| site_id | KC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CU1 I 801 |
| Chain | Residue |
| I | CYS399 |
| I | CYS495 |
| I | SO2802 |
| I | HEM807 |
| site_id | KC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO2 I 802 |
| Chain | Residue |
| I | LYS208 |
| I | TYR285 |
| I | ARG366 |
| I | LYS393 |
| I | CYS399 |
| I | CU1801 |
| I | HEM807 |
| I | HOH1118 |
| site_id | KC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE BU3 I 803 |
| Chain | Residue |
| I | ILE357 |
| site_id | KC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE BU3 I 804 |
| Chain | Residue |
| I | LYS288 |
| I | SER394 |
| I | ARG539 |
| I | ASP540 |
| site_id | LC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT I 805 |
| Chain | Residue |
| I | ASN359 |
| I | GLN365 |
| I | GLY403 |
| I | TYR412 |
| I | HOH1117 |
| site_id | LC2 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE HEM I 806 |
| Chain | Residue |
| I | CYS143 |
| I | CYS146 |
| I | HIS147 |
| I | GLU340 |
| I | HIS343 |
| I | GLY346 |
| I | GLY347 |
| I | HIS348 |
| I | LEU349 |
| I | HEM808 |
| I | HOH911 |
| J | ARG124 |
| J | VAL125 |
| J | ALA126 |
| J | ILE357 |
| J | SER358 |
| J | ASN359 |
| J | CYS360 |
| J | GLU361 |
| J | ARG362 |
| J | HOH925 |
| site_id | LC3 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM I 807 |
| Chain | Residue |
| I | TYR123 |
| I | VAL202 |
| I | GLY203 |
| I | HIS204 |
| I | ARG206 |
| I | THR207 |
| I | LYS208 |
| I | ARG218 |
| I | TYR301 |
| I | CYS302 |
| I | CYS305 |
| I | HIS306 |
| I | CYS363 |
| I | HIS364 |
| I | CYS399 |
| I | GLY400 |
| I | GLU402 |
| I | CYS495 |
| I | ARG513 |
| I | CU1801 |
| I | SO2802 |
| I | HEM809 |
| I | HEM810 |
| site_id | LC4 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE HEM I 808 |
| Chain | Residue |
| I | HIS147 |
| I | TYR151 |
| I | TRP154 |
| I | HIS159 |
| I | VAL337 |
| I | CYS339 |
| I | CYS342 |
| I | HIS343 |
| I | SER358 |
| I | ALA419 |
| I | PRO424 |
| I | HIS425 |
| I | LYS459 |
| I | HEM806 |
| I | HEM809 |
| I | HOH912 |
| I | HOH930 |
| J | ASN359 |
| J | GLU361 |
| J | ARG417 |
| J | HOH914 |
| J | HOH1060 |
| site_id | LC5 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE HEM I 809 |
| Chain | Residue |
| I | ARG158 |
| I | HIS159 |
| I | THR162 |
| I | HIS204 |
| I | VAL304 |
| I | CYS305 |
| I | HIS306 |
| I | VAL337 |
| I | CYS360 |
| I | ARG362 |
| I | CYS363 |
| I | HIS364 |
| I | VAL427 |
| I | THR428 |
| I | SER454 |
| I | ARG513 |
| I | HEM807 |
| I | HEM808 |
| I | HEM810 |
| site_id | LC6 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE HEM I 810 |
| Chain | Residue |
| I | ARG206 |
| I | HIS364 |
| I | GLU402 |
| I | GLY403 |
| I | HIS411 |
| I | MET416 |
| I | ARG417 |
| I | CYS418 |
| I | CYS421 |
| I | HIS422 |
| I | SER454 |
| I | LYS455 |
| I | PRO456 |
| I | LEU458 |
| I | PHE491 |
| I | ARG513 |
| I | ARG514 |
| I | HIS516 |
| I | TRP518 |
| I | HEM807 |
| I | HEM809 |
| I | HEM811 |
| I | HOH907 |
| I | HOH913 |
| I | HOH937 |
| site_id | LC7 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE HEM I 811 |
| Chain | Residue |
| I | HIS411 |
| I | MET416 |
| I | LYS460 |
| I | CYS462 |
| I | CYS465 |
| I | HIS466 |
| I | HIS488 |
| I | MET489 |
| I | TRP518 |
| I | ARG553 |
| I | HEM810 |
| I | HEM812 |
| I | HOH1032 |
| I | HOH1053 |
| I | HOH1064 |
| site_id | LC8 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE HEM I 812 |
| Chain | Residue |
| I | CYS462 |
| I | THR463 |
| I | HIS466 |
| I | GLN469 |
| I | GLN473 |
| I | HIS479 |
| I | CYS484 |
| I | CYS487 |
| I | HIS488 |
| I | ILE520 |
| I | GLN606 |
| I | ASP657 |
| I | GLY658 |
| I | TRP660 |
| I | HIS663 |
| I | HEM811 |
| I | HOH909 |
| I | HOH949 |
| I | HOH1048 |
| I | HOH1095 |
| site_id | LC9 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE HEM I 813 |
| Chain | Residue |
| I | THR478 |
| I | HIS479 |
| I | ASN482 |
| I | SER486 |
| I | LEU558 |
| I | ALA561 |
| I | CYS562 |
| I | ALA575 |
| I | CYS578 |
| I | HIS579 |
| I | GLU601 |
| I | VAL602 |
| I | TRP605 |
| site_id | MC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CU1 J 801 |
| Chain | Residue |
| J | CYS399 |
| J | CYS495 |
| J | SX802 |
| J | HEM807 |
| site_id | MC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SX J 802 |
| Chain | Residue |
| J | ARG366 |
| J | LYS393 |
| J | CYS399 |
| J | CU1801 |
| J | HEM807 |
| J | HOH1012 |
| J | HOH1057 |
| site_id | MC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE BU3 J 803 |
| Chain | Residue |
| J | ILE357 |
| J | SER358 |
| J | ASN359 |
| J | HOH914 |
| site_id | MC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BU3 J 804 |
| Chain | Residue |
| J | SER394 |
| J | ASP540 |
| J | GLY541 |
| site_id | MC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT J 805 |
| Chain | Residue |
| J | ASN359 |
| J | GLN365 |
| J | GLY403 |
| J | THR406 |
| J | TYR412 |
| J | HOH977 |
| site_id | MC6 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE HEM J 806 |
| Chain | Residue |
| F | ARG124 |
| F | VAL125 |
| F | ILE357 |
| F | SER358 |
| F | ASN359 |
| F | CYS360 |
| F | GLU361 |
| F | ARG362 |
| F | BU3803 |
| F | HOH932 |
| F | HOH1093 |
| J | ILE138 |
| J | CYS143 |
| J | CYS146 |
| J | HIS147 |
| J | HIS343 |
| J | GLY346 |
| J | HIS348 |
| J | LEU349 |
| J | HEM808 |
| J | HOH941 |
| site_id | MC7 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE HEM J 807 |
| Chain | Residue |
| J | TYR123 |
| J | VAL202 |
| J | HIS204 |
| J | ARG206 |
| J | THR207 |
| J | LYS208 |
| J | ARG218 |
| J | TYR301 |
| J | CYS302 |
| J | CYS305 |
| J | HIS306 |
| J | CYS363 |
| J | HIS364 |
| J | CYS399 |
| J | GLY400 |
| J | GLU402 |
| J | ARG513 |
| J | CU1801 |
| J | SX802 |
| J | HEM809 |
| J | HEM810 |
| site_id | MC8 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE HEM J 808 |
| Chain | Residue |
| F | ASN359 |
| F | GLU361 |
| F | ARG417 |
| F | BU3803 |
| F | HOH913 |
| J | HIS147 |
| J | TYR151 |
| J | TRP154 |
| J | HIS159 |
| J | VAL337 |
| J | SER338 |
| J | CYS339 |
| J | CYS342 |
| J | HIS343 |
| J | ILE357 |
| J | SER358 |
| J | ALA419 |
| J | PRO424 |
| J | HIS425 |
| J | LYS459 |
| J | HEM806 |
| J | HEM809 |
| J | HOH902 |
| J | HOH929 |
| J | HOH1001 |
| site_id | MC9 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE HEM J 809 |
| Chain | Residue |
| J | ARG158 |
| J | HIS159 |
| J | THR162 |
| J | HIS204 |
| J | VAL304 |
| J | CYS305 |
| J | HIS306 |
| J | VAL337 |
| J | CYS360 |
| J | ARG362 |
| J | CYS363 |
| J | HIS364 |
| J | VAL427 |
| J | THR428 |
| J | SER454 |
| J | ARG513 |
| J | HEM807 |
| J | HEM808 |
| J | HEM810 |
| site_id | NC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM J 810 |
| Chain | Residue |
| J | ARG206 |
| J | HIS364 |
| J | GLU402 |
| J | GLY403 |
| J | MET416 |
| J | CYS418 |
| J | CYS421 |
| J | HIS422 |
| J | SER454 |
| J | LYS455 |
| J | LEU458 |
| J | PHE491 |
| J | ARG513 |
| J | ARG514 |
| J | HIS516 |
| J | TRP518 |
| J | HEM807 |
| J | HEM809 |
| J | HEM811 |
| J | HOH908 |
| J | HOH985 |
| J | HOH991 |
| J | HOH1049 |
| site_id | NC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE HEM J 811 |
| Chain | Residue |
| I | ASP464 |
| J | HIS411 |
| J | LYS414 |
| J | MET416 |
| J | LYS460 |
| J | CYS462 |
| J | CYS465 |
| J | HIS466 |
| J | HIS488 |
| J | TRP518 |
| J | ARG553 |
| J | HEM810 |
| J | HEM812 |
| J | HOH919 |
| J | HOH957 |
| J | HOH984 |
| J | HOH995 |
| site_id | NC3 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE HEM J 812 |
| Chain | Residue |
| J | CYS462 |
| J | THR463 |
| J | HIS466 |
| J | HIS479 |
| J | CYS484 |
| J | CYS487 |
| J | HIS488 |
| J | ILE520 |
| J | GLN606 |
| J | ASP657 |
| J | GLY658 |
| J | TRP660 |
| J | HIS663 |
| J | HEM811 |
| J | HOH912 |
| J | HOH920 |
| J | HOH932 |
| J | HOH949 |
| site_id | NC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE HEM J 813 |
| Chain | Residue |
| J | THR478 |
| J | HIS479 |
| J | ASN482 |
| J | LEU558 |
| J | ALA561 |
| J | CYS562 |
| J | ALA575 |
| J | CYS578 |
| J | HIS579 |
| J | LEU586 |
| J | GLU601 |
| J | VAL602 |
| J | TRP605 |
| site_id | NC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CU1 K 801 |
| Chain | Residue |
| K | CYS399 |
| K | CYS495 |
| K | SX802 |
| K | HEM807 |
| site_id | NC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SX K 802 |
| Chain | Residue |
| K | ARG366 |
| K | LYS393 |
| K | CYS399 |
| K | CU1801 |
| K | HEM807 |
| K | HOH1043 |
| site_id | NC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BU3 K 803 |
| Chain | Residue |
| D | HEM806 |
| K | ILE357 |
| K | ASN359 |
| site_id | NC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BU3 K 804 |
| Chain | Residue |
| K | LYS288 |
| K | SER394 |
| K | ASP540 |
| site_id | NC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT K 805 |
| Chain | Residue |
| K | ASN359 |
| K | GLN365 |
| K | GLY403 |
| K | THR406 |
| K | TYR412 |
| K | HOH1057 |
| site_id | OC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE HEM K 806 |
| Chain | Residue |
| E | TYR59 |
| E | ARG124 |
| E | VAL125 |
| E | ILE357 |
| E | SER358 |
| E | ASN359 |
| E | CYS360 |
| E | GLU361 |
| E | ARG362 |
| E | HOH910 |
| E | HOH1065 |
| K | CYS143 |
| K | CYS146 |
| K | HIS147 |
| K | HIS343 |
| K | GLY346 |
| K | GLY347 |
| K | HIS348 |
| K | LEU349 |
| K | HEM808 |
| K | HOH909 |
| site_id | OC2 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM K 807 |
| Chain | Residue |
| K | TYR123 |
| K | ARG158 |
| K | VAL202 |
| K | GLY203 |
| K | HIS204 |
| K | ARG206 |
| K | THR207 |
| K | LYS208 |
| K | ARG218 |
| K | TYR301 |
| K | CYS302 |
| K | CYS305 |
| K | HIS306 |
| K | CYS363 |
| K | HIS364 |
| K | CYS399 |
| K | GLY400 |
| K | GLU402 |
| K | ARG513 |
| K | CU1801 |
| K | SX802 |
| K | HEM809 |
| K | HEM810 |
| site_id | OC3 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE HEM K 808 |
| Chain | Residue |
| E | ASN359 |
| E | GLU361 |
| E | ARG417 |
| E | HOH934 |
| K | HIS147 |
| K | TYR151 |
| K | TRP154 |
| K | HIS159 |
| K | VAL337 |
| K | SER338 |
| K | CYS339 |
| K | CYS342 |
| K | HIS343 |
| K | SER358 |
| K | ALA419 |
| K | PRO424 |
| K | HIS425 |
| K | LYS459 |
| K | HEM806 |
| K | HEM809 |
| K | HOH903 |
| K | HOH904 |
| K | HOH916 |
| K | HOH1049 |
| site_id | OC4 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE HEM K 809 |
| Chain | Residue |
| K | ARG158 |
| K | HIS159 |
| K | THR162 |
| K | HIS204 |
| K | VAL304 |
| K | CYS305 |
| K | HIS306 |
| K | VAL337 |
| K | CYS342 |
| K | CYS360 |
| K | ARG362 |
| K | CYS363 |
| K | HIS364 |
| K | VAL427 |
| K | THR428 |
| K | SER454 |
| K | ARG513 |
| K | HEM807 |
| K | HEM808 |
| K | HEM810 |
| site_id | OC5 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE HEM K 810 |
| Chain | Residue |
| K | ARG206 |
| K | HIS364 |
| K | GLU402 |
| K | GLY403 |
| K | HIS411 |
| K | MET416 |
| K | ARG417 |
| K | CYS418 |
| K | CYS421 |
| K | HIS422 |
| K | SER454 |
| K | LYS455 |
| K | LEU458 |
| K | PHE491 |
| K | ARG513 |
| K | ARG514 |
| K | HIS516 |
| K | TRP518 |
| K | HEM807 |
| K | HEM809 |
| K | HEM811 |
| K | HOH919 |
| K | HOH932 |
| K | HOH951 |
| site_id | OC6 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE HEM K 811 |
| Chain | Residue |
| K | HIS411 |
| K | LYS414 |
| K | MET416 |
| K | CYS462 |
| K | CYS465 |
| K | HIS466 |
| K | HIS488 |
| K | TRP518 |
| K | ARG553 |
| K | HEM810 |
| K | HEM812 |
| K | HOH923 |
| K | HOH924 |
| site_id | OC7 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE HEM K 812 |
| Chain | Residue |
| K | CYS462 |
| K | THR463 |
| K | HIS466 |
| K | GLN469 |
| K | GLN473 |
| K | HIS479 |
| K | CYS484 |
| K | CYS487 |
| K | HIS488 |
| K | ILE520 |
| K | GLN606 |
| K | ASP657 |
| K | GLY658 |
| K | TRP660 |
| K | HIS663 |
| K | HEM811 |
| K | HOH902 |
| K | HOH944 |
| K | HOH953 |
| K | HOH961 |
| K | HOH983 |
| K | HOH988 |
| site_id | OC8 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE HEM K 813 |
| Chain | Residue |
| K | THR478 |
| K | HIS479 |
| K | ASN482 |
| K | ALA561 |
| K | CYS562 |
| K | ALA575 |
| K | CYS578 |
| K | HIS579 |
| K | PHE592 |
| K | GLU601 |
| K | VAL602 |
| K | TRP605 |
| site_id | OC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CU1 L 801 |
| Chain | Residue |
| L | CYS399 |
| L | CYS495 |
| L | SX802 |
| L | HEM807 |
| site_id | PC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SX L 802 |
| Chain | Residue |
| L | ARG366 |
| L | LYS393 |
| L | CYS399 |
| L | CU1801 |
| L | HEM807 |
| L | HOH975 |
| site_id | PC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BU3 L 803 |
| Chain | Residue |
| L | ILE357 |
| L | ASN359 |
| site_id | PC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BU3 L 804 |
| Chain | Residue |
| L | LYS288 |
| L | SER394 |
| L | ASP540 |
| site_id | PC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT L 805 |
| Chain | Residue |
| L | GLN365 |
| L | GLY403 |
| L | THR406 |
| L | TYR412 |
| L | HOH1023 |
| site_id | PC5 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE HEM L 806 |
| Chain | Residue |
| G | ARG124 |
| G | VAL125 |
| G | ILE357 |
| G | SER358 |
| G | ASN359 |
| G | CYS360 |
| G | GLU361 |
| G | ARG362 |
| G | HOH919 |
| G | HOH1065 |
| L | CYS143 |
| L | CYS146 |
| L | HIS147 |
| L | GLU340 |
| L | HIS343 |
| L | GLY346 |
| L | GLY347 |
| L | HIS348 |
| L | LEU349 |
| L | HEM808 |
| L | HOH903 |
| site_id | PC6 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE HEM L 807 |
| Chain | Residue |
| L | TYR123 |
| L | VAL202 |
| L | GLY203 |
| L | HIS204 |
| L | ARG206 |
| L | THR207 |
| L | LYS208 |
| L | PHE212 |
| L | ARG218 |
| L | TYR301 |
| L | CYS302 |
| L | CYS305 |
| L | HIS306 |
| L | CYS363 |
| L | HIS364 |
| L | CYS399 |
| L | GLY400 |
| L | GLU402 |
| L | CYS495 |
| L | ARG513 |
| L | CU1801 |
| L | SX802 |
| L | HEM809 |
| L | HEM810 |
| site_id | PC7 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE HEM L 808 |
| Chain | Residue |
| G | ASN359 |
| G | GLU361 |
| G | ARG417 |
| G | HOH965 |
| L | HIS147 |
| L | TYR151 |
| L | TRP154 |
| L | HIS159 |
| L | VAL337 |
| L | CYS339 |
| L | CYS342 |
| L | HIS343 |
| L | SER358 |
| L | ALA419 |
| L | PRO424 |
| L | HIS425 |
| L | LYS459 |
| L | HEM806 |
| L | HEM809 |
| L | HOH908 |
| L | HOH997 |
| L | HOH998 |
| site_id | PC8 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE HEM L 809 |
| Chain | Residue |
| L | ARG158 |
| L | HIS159 |
| L | THR162 |
| L | HIS204 |
| L | VAL304 |
| L | CYS305 |
| L | HIS306 |
| L | VAL337 |
| L | CYS360 |
| L | CYS363 |
| L | HIS364 |
| L | VAL427 |
| L | THR428 |
| L | SER454 |
| L | ARG513 |
| L | HEM807 |
| L | HEM808 |
| L | HEM810 |
| site_id | PC9 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE HEM L 810 |
| Chain | Residue |
| L | ARG206 |
| L | HIS364 |
| L | GLU402 |
| L | GLY403 |
| L | MET416 |
| L | ARG417 |
| L | CYS418 |
| L | CYS421 |
| L | HIS422 |
| L | SER454 |
| L | LYS455 |
| L | LEU458 |
| L | PHE491 |
| L | ARG513 |
| L | ARG514 |
| L | HIS516 |
| L | TRP518 |
| L | HEM807 |
| L | HEM809 |
| L | HEM811 |
| L | HOH1000 |
| L | HOH1018 |
| site_id | QC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE HEM L 811 |
| Chain | Residue |
| L | HIS411 |
| L | MET416 |
| L | LYS460 |
| L | GLU461 |
| L | CYS462 |
| L | CYS465 |
| L | HIS466 |
| L | HIS488 |
| L | MET489 |
| L | TRP518 |
| L | ARG553 |
| L | HEM810 |
| L | HEM812 |
| L | HOH981 |
| L | HOH986 |
| site_id | QC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE HEM L 812 |
| Chain | Residue |
| L | CYS462 |
| L | THR463 |
| L | HIS466 |
| L | GLN469 |
| L | GLN473 |
| L | HIS479 |
| L | CYS484 |
| L | CYS487 |
| L | HIS488 |
| L | ILE520 |
| L | GLN606 |
| L | ASP657 |
| L | GLY658 |
| L | HIS663 |
| L | HEM811 |
| L | HOH909 |
| L | HOH935 |
| L | HOH1003 |
| L | HOH1004 |
| site_id | QC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE HEM L 813 |
| Chain | Residue |
| L | THR478 |
| L | HIS479 |
| L | ASN482 |
| L | SER486 |
| L | CYS487 |
| L | LEU558 |
| L | ALA561 |
| L | CYS562 |
| L | ALA575 |
| L | CYS578 |
| L | HIS579 |
| L | LEU590 |
| L | VAL602 |
| site_id | QC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CU1 G 801 |
| Chain | Residue |
| G | CYS399 |
| G | CYS495 |
| G | SX802 |
| G | HEM807 |
| G | SO2814 |
| site_id | QC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SX G 802 |
| Chain | Residue |
| G | ARG366 |
| G | LYS393 |
| G | CYS399 |
| G | CU1801 |
| G | HEM807 |
| G | SO2814 |
| G | HOH1076 |
| G | HOH1132 |
| site_id | QC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE BU3 G 803 |
| Chain | Residue |
| G | ILE357 |
| site_id | QC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BU3 G 804 |
| Chain | Residue |
| G | SER394 |
| G | ASP540 |
| G | GLY541 |
| site_id | QC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT G 805 |
| Chain | Residue |
| G | ASN359 |
| G | GLN365 |
| G | GLY403 |
| G | TYR412 |
| G | HOH1121 |
| site_id | QC9 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE HEM G 806 |
| Chain | Residue |
| G | CYS143 |
| G | CYS146 |
| G | HIS147 |
| G | GLU340 |
| G | HIS343 |
| G | GLY346 |
| G | GLY347 |
| G | HIS348 |
| G | LEU349 |
| G | HEM808 |
| G | HOH958 |
| H | TYR59 |
| H | ARG124 |
| H | VAL125 |
| H | ALA126 |
| H | ILE357 |
| H | SER358 |
| H | ASN359 |
| H | CYS360 |
| H | GLU361 |
| H | ARG362 |
| H | HOH1096 |
| site_id | RC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE HEM G 807 |
| Chain | Residue |
| G | TYR123 |
| G | VAL202 |
| G | GLY203 |
| G | HIS204 |
| G | ARG206 |
| G | THR207 |
| G | LYS208 |
| G | ARG218 |
| G | TYR301 |
| G | CYS302 |
| G | CYS305 |
| G | HIS306 |
| G | CYS363 |
| G | HIS364 |
| G | CYS399 |
| G | GLY400 |
| G | GLU402 |
| G | CYS495 |
| G | ARG513 |
| G | CU1801 |
| G | SX802 |
| G | HEM809 |
| G | HEM810 |
| G | SO2814 |
| site_id | RC2 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM G 808 |
| Chain | Residue |
| G | HIS147 |
| G | TYR151 |
| G | TRP154 |
| G | HIS159 |
| G | VAL337 |
| G | CYS339 |
| G | CYS342 |
| G | HIS343 |
| G | SER358 |
| G | ALA419 |
| G | PRO424 |
| G | HIS425 |
| G | LYS459 |
| G | HEM806 |
| G | HEM809 |
| G | HOH907 |
| G | HOH1030 |
| G | HOH1090 |
| G | HOH1092 |
| H | ASN359 |
| H | GLU361 |
| H | ARG417 |
| H | HOH1126 |
| site_id | RC3 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE HEM G 809 |
| Chain | Residue |
| G | ARG158 |
| G | HIS159 |
| G | THR162 |
| G | HIS204 |
| G | CYS305 |
| G | HIS306 |
| G | VAL337 |
| G | CYS360 |
| G | CYS363 |
| G | HIS364 |
| G | VAL427 |
| G | THR428 |
| G | SER454 |
| G | ARG513 |
| G | HEM807 |
| G | HEM808 |
| G | HEM810 |
| site_id | RC4 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE HEM G 810 |
| Chain | Residue |
| G | ARG206 |
| G | HIS364 |
| G | GLU402 |
| G | GLY403 |
| G | MET416 |
| G | ARG417 |
| G | CYS418 |
| G | CYS421 |
| G | HIS422 |
| G | SER454 |
| G | LYS455 |
| G | PRO456 |
| G | LEU458 |
| G | MET489 |
| G | PHE491 |
| G | ARG513 |
| G | ARG514 |
| G | HIS516 |
| G | TRP518 |
| G | HEM807 |
| G | HEM809 |
| G | HOH989 |
| G | HOH1113 |
| G | HOH1115 |
| site_id | RC5 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE HEM G 811 |
| Chain | Residue |
| G | HIS411 |
| G | MET416 |
| G | LYS460 |
| G | CYS462 |
| G | CYS465 |
| G | HIS466 |
| G | HIS488 |
| G | TRP518 |
| G | ARG553 |
| G | HEM812 |
| G | HOH1051 |
| G | HOH1069 |
| site_id | RC6 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE HEM G 812 |
| Chain | Residue |
| G | CYS462 |
| G | THR463 |
| G | HIS466 |
| G | GLN469 |
| G | GLN473 |
| G | HIS479 |
| G | CYS484 |
| G | CYS487 |
| G | HIS488 |
| G | ILE520 |
| G | GLN606 |
| G | ASP657 |
| G | GLY658 |
| G | TRP660 |
| G | HIS663 |
| G | HEM811 |
| G | HOH911 |
| G | HOH952 |
| G | HOH968 |
| G | HOH1119 |
| G | HOH1120 |
| site_id | RC7 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE HEM G 813 |
| Chain | Residue |
| G | THR478 |
| G | HIS479 |
| G | ASN482 |
| G | SER486 |
| G | CYS487 |
| G | ALA561 |
| G | CYS562 |
| G | ALA575 |
| G | CYS578 |
| G | HIS579 |
| G | LEU590 |
| G | GLU601 |
| G | VAL602 |
| G | TRP605 |
| site_id | RC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO2 G 814 |
| Chain | Residue |
| G | LYS208 |
| G | TYR285 |
| G | LYS393 |
| G | CU1801 |
| G | SX802 |
| G | HEM807 |
| G | HOH1076 |
| G | HOH1132 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 180 |
| Details | Binding site: {"description":"covalent","evidences":[{"source":"PDB","id":"4RKN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 180 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"source":"PDB","id":"4RKN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 36 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"4RKN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | Binding site: {"description":"covalent","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25642962","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4RKM","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
