4RKD

Psychrophilic aromatic amino acids aminotransferase from Psychrobacter sp. B6 cocrystalized with aspartic acid

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004838	molecular_function	L-tyrosine:2-oxoglutarate transaminase activity
A	0005829	cellular_component	cytosol
A	0006520	biological_process	amino acid metabolic process
A	0008483	molecular_function	transaminase activity
A	0009058	biological_process	biosynthetic process
A	0030170	molecular_function	pyridoxal phosphate binding
A	0042802	molecular_function	identical protein binding
B	0003824	molecular_function	catalytic activity
B	0004838	molecular_function	L-tyrosine:2-oxoglutarate transaminase activity
B	0005829	cellular_component	cytosol
B	0006520	biological_process	amino acid metabolic process
B	0008483	molecular_function	transaminase activity
B	0009058	biological_process	biosynthetic process
B	0030170	molecular_function	pyridoxal phosphate binding
B	0042802	molecular_function	identical protein binding
C	0003824	molecular_function	catalytic activity
C	0004838	molecular_function	L-tyrosine:2-oxoglutarate transaminase activity
C	0005829	cellular_component	cytosol
C	0006520	biological_process	amino acid metabolic process
C	0008483	molecular_function	transaminase activity
C	0009058	biological_process	biosynthetic process
C	0030170	molecular_function	pyridoxal phosphate binding
C	0042802	molecular_function	identical protein binding
D	0003824	molecular_function	catalytic activity
D	0004838	molecular_function	L-tyrosine:2-oxoglutarate transaminase activity
D	0005829	cellular_component	cytosol
D	0006520	biological_process	amino acid metabolic process
D	0008483	molecular_function	transaminase activity
D	0009058	biological_process	biosynthetic process
D	0030170	molecular_function	pyridoxal phosphate binding
D	0042802	molecular_function	identical protein binding
E	0003824	molecular_function	catalytic activity
E	0004838	molecular_function	L-tyrosine:2-oxoglutarate transaminase activity
E	0005829	cellular_component	cytosol
E	0006520	biological_process	amino acid metabolic process
E	0008483	molecular_function	transaminase activity
E	0009058	biological_process	biosynthetic process
E	0030170	molecular_function	pyridoxal phosphate binding
E	0042802	molecular_function	identical protein binding
F	0003824	molecular_function	catalytic activity
F	0004838	molecular_function	L-tyrosine:2-oxoglutarate transaminase activity
F	0005829	cellular_component	cytosol
F	0006520	biological_process	amino acid metabolic process
F	0008483	molecular_function	transaminase activity
F	0009058	biological_process	biosynthetic process
F	0030170	molecular_function	pyridoxal phosphate binding
F	0042802	molecular_function	identical protein binding
G	0003824	molecular_function	catalytic activity
G	0004838	molecular_function	L-tyrosine:2-oxoglutarate transaminase activity
G	0005829	cellular_component	cytosol
G	0006520	biological_process	amino acid metabolic process
G	0008483	molecular_function	transaminase activity
G	0009058	biological_process	biosynthetic process
G	0030170	molecular_function	pyridoxal phosphate binding
G	0042802	molecular_function	identical protein binding
H	0003824	molecular_function	catalytic activity
H	0004838	molecular_function	L-tyrosine:2-oxoglutarate transaminase activity
H	0005829	cellular_component	cytosol
H	0006520	biological_process	amino acid metabolic process
H	0008483	molecular_function	transaminase activity
H	0009058	biological_process	biosynthetic process
H	0030170	molecular_function	pyridoxal phosphate binding
H	0042802	molecular_function	identical protein binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 401

Chain	Residue
A	HOH528
A	HOH530
A	HOH533
A	HOH594
B	HOH551
B	HOH552

---

site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE PLP A 402

Chain	Residue
A	TRP130
A	ASP211
A	ALA213
A	TYR214
A	SER243
A	SER245
A	LYS246
A	ARG254
B	TYR65
A	GLY102
A	GLY103
A	SER104

---

site_id	AC3
Number of Residues	14
Details	BINDING SITE FOR RESIDUE KET A 403

Chain	Residue
A	GLY34
A	GLY102
A	GLY103
A	SER104
A	TRP130
A	ASN183
A	ASP211
A	TYR214
A	SER243
A	SER245
A	LYS246
A	ARG254
B	TYR65
B	ARG280

---

site_id	AC4
Number of Residues	12
Details	BINDING SITE FOR RESIDUE PLP B 401

Chain	Residue
A	TYR65
B	GLY102
B	GLY103
B	SER104
B	ASN183
B	ASP211
B	ALA213
B	TYR214
B	SER243
B	SER245
B	LYS246
B	ARG254

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 401

Chain	Residue
C	HOH523
C	HOH569
C	HOH575
D	HOH542
D	HOH569

---

site_id	AC6
Number of Residues	14
Details	BINDING SITE FOR RESIDUE PLP C 402

Chain	Residue
C	GLY102
C	GLY103
C	SER104
C	TRP130
C	ASN183
C	ASP211
C	TYR214
C	SER243
C	SER245
C	LYS246
C	ARG254
C	HOH573
C	HOH574
D	TYR65

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE OAA C 403

Chain	Residue
C	TYR65
C	ARG280
C	HOH570
D	TRP130
D	PMP401

---

site_id	AC8
Number of Residues	15
Details	BINDING SITE FOR RESIDUE PMP D 401

Chain	Residue
C	TYR65
C	OAA403
D	GLY102
D	GLY103
D	SER104
D	TRP130
D	ASN183
D	ASP211
D	ALA213
D	TYR214
D	SER243
D	SER245
D	LYS246
D	ARG254
D	HOH615

---

site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG E 401

Chain	Residue
E	GLU112
E	HOH523
E	HOH524
F	GLU112
F	HOH543
F	HOH545
F	HOH567

---

site_id	BC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE PLP E 402

Chain	Residue
E	LYS246
E	ARG254
F	TYR65
E	GLY102
E	GLY103
E	SER104
E	ASN183
E	ASP211
E	ALA213
E	TYR214
E	SER243
E	SER245

---

site_id	BC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE OAA E 403

Chain	Residue
E	GLU138
E	ASP141
E	ILE142
E	GLU143
E	HOH543
E	HOH544
E	HOH562

---

site_id	BC3
Number of Residues	14
Details	BINDING SITE FOR RESIDUE KET E 404

Chain	Residue
E	GLY34
E	GLY102
E	GLY103
E	SER104
E	TRP130
E	ASN183
E	ASP211
E	TYR214
E	SER243
E	SER245
E	LYS246
E	ARG254
E	HOH568
F	TYR65

---

site_id	BC4
Number of Residues	14
Details	BINDING SITE FOR RESIDUE PLP F 401

Chain	Residue
E	TYR65
F	GLY102
F	GLY103
F	SER104
F	TRP130
F	HIS133
F	ASN183
F	ASP211
F	ALA213
F	TYR214
F	SER243
F	SER245
F	LYS246
F	ARG254

---

site_id	BC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG G 401

Chain	Residue
G	HOH543
G	HOH563
H	HOH543
H	HOH544
H	HOH570
H	HOH571

---

site_id	BC6
Number of Residues	13
Details	BINDING SITE FOR RESIDUE KET G 402

Chain	Residue
G	GLY102
G	GLY103
G	SER104
G	TRP130
G	ASN183
G	ASP211
G	TYR214
G	SER243
G	SER245
G	LYS246
G	ARG254
G	ARG374
H	TYR65

---

site_id	BC7
Number of Residues	14
Details	BINDING SITE FOR RESIDUE PMP H 401

Chain	Residue
G	TYR65
H	GLY102
H	GLY103
H	SER104
H	TRP130
H	ASN183
H	ASP211
H	ALA213
H	TYR214
H	SER243
H	SER245
H	LYS246
H	ARG254
H	HOH574

---

Functional Information from PROSITE/UniProt

site_id	PS00105
Number of Residues	14
Details	AA_TRANSFER_CLASS_1 Aminotransferases class-I pyridoxal-phosphate attachment site. SFSKnlSLyGERVG

Chain	Residue	Details
A	SER243-GLY256

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