4RG3

Epsilon-caprolactone-bound crystal structure of cyclohexanone monooxygenase in the Tight conformation

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004497	molecular_function	monooxygenase activity
A	0004499	molecular_function	N,N-dimethylaniline monooxygenase activity
A	0016709	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
A	0050660	molecular_function	flavin adenine dinucleotide binding
A	0050661	molecular_function	NADP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	36
Details	BINDING SITE FOR RESIDUE FAD A 601

Chain	Residue
A	ILE14
A	TRP48
A	TRP50
A	ASN51
A	TYR53
A	SER58
A	ASP59
A	THR60
A	TYR65
A	GLU111
A	VAL112
A	GLY15
A	ALA142
A	VAL143
A	GLY144
A	ASN388
A	ILE392
A	LEU428
A	ASN436
A	LEU437
A	NAP602
A	ECE603
A	GLY17
A	BCN604
A	HOH703
A	HOH720
A	HOH732
A	HOH744
A	HOH768
A	HOH799
A	PHE18
A	GLY19
A	ASP39
A	LYS40
A	GLY46
A	THR47

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site_id	AC2
Number of Residues	34
Details	BINDING SITE FOR RESIDUE NAP A 602

Chain	Residue
A	TYR53
A	LEU57
A	SER58
A	ASP59
A	LEU146
A	PRO152
A	ILE184
A	GLY185
A	THR186
A	GLY187
A	SER188
A	THR189
A	GLN192
A	ARG209
A	THR210
A	ARG329
A	ILE350
A	ALA379
A	THR380
A	GLY381
A	TRP492
A	FAD601
A	ECE603
A	HOH707
A	HOH709
A	HOH718
A	HOH726
A	HOH730
A	HOH734
A	HOH738
A	HOH739
A	HOH740
A	HOH778
A	HOH779

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ECE A 603

Chain	Residue
A	PHE279
A	ARG329
A	PHE434
A	THR435
A	FAD601
A	NAP602

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site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE BCN A 604

Chain	Residue
A	LYS40
A	TRP50
A	SER147
A	ALA168
A	ASN388
A	FAD601

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