4RFQ
Human Methyltransferase-Like 18
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE SAM A 401 |
| Chain | Residue |
| A | PRO78 |
| A | GLN216 |
| A | ASP217 |
| A | TYR218 |
| A | GLY268 |
| A | GLU269 |
| A | TRP270 |
| A | SER293 |
| A | THR295 |
| A | TYR301 |
| A | HOH507 |
| A | GLU89 |
| A | HOH509 |
| A | HOH510 |
| A | HOH521 |
| A | PRO90 |
| A | ILE168 |
| A | TRP169 |
| A | THR172 |
| A | GLY195 |
| A | CYS196 |
| A | GLY197 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|Ref.14, ECO:0007744|PDB:4RFQ |
| Chain | Residue | Details |
| A | ALA187 | |
| A | SER235 | |
| A | TYR287 | |
| A | LEU312 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|Ref.14, ECO:0000305|PubMed:35674491, ECO:0007744|PDB:4RFQ |
| Chain | Residue | Details |
| A | HIS214 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:17525332, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER72 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER77 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Tele-methylhistidine; by autocatalysis => ECO:0000269|PubMed:33693809 |
| Chain | Residue | Details |
| A | PHE173 |
