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Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4REU

Revelation of Endogenously bound Fe2+ ions in the Crystal Structure of Ferritin from Escherichia coli

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006826	biological_process	iron ion transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0008199	molecular_function	ferric iron binding
B	0006826	biological_process	iron ion transport
B	0006879	biological_process	intracellular iron ion homeostasis
B	0008199	molecular_function	ferric iron binding
C	0006826	biological_process	iron ion transport
C	0006879	biological_process	intracellular iron ion homeostasis
C	0008199	molecular_function	ferric iron binding
D	0006826	biological_process	iron ion transport
D	0006879	biological_process	intracellular iron ion homeostasis
D	0008199	molecular_function	ferric iron binding
E	0006826	biological_process	iron ion transport
E	0006879	biological_process	intracellular iron ion homeostasis
E	0008199	molecular_function	ferric iron binding
F	0006826	biological_process	iron ion transport
F	0006879	biological_process	intracellular iron ion homeostasis
F	0008199	molecular_function	ferric iron binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE A 201

Chain	Residue
A	GLU17
A	GLU50
A	HIS53
A	FE202
A	HOH301
A	HOH312

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE A 202

Chain	Residue
A	FE201
A	HOH301
A	GLU50
A	GLU94
A	GLU130

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 203

Chain	Residue
A	HIS93
A	LEU96
A	HOH306

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 204

Chain	Residue
A	ALA78
A	GLU89

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 205

Chain	Residue
A	GLU79
A	TYR80
A	GLU85

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 206

Chain	Residue
B	GLU74
F	GLU103

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 207

Chain	Residue
A	ILE7
A	GLU8
A	LEU67

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MES A 208

Chain	Residue
A	GLU12
A	TYR19
A	ASN71
A	HOH315

site_id	AC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 209

Chain	Residue
C	HG205

site_id	BC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 210

Chain	Residue
C	HG205

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 211

Chain	Residue
A	THR72
A	HOH329
D	GLN112

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 212

Chain	Residue
A	GLN112
E	THR72
E	HOH331

site_id	BC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 213

Chain	Residue
A	ASN102

site_id	BC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 214

Chain	Residue
A	GLU74
A	HOH313

site_id	BC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE B 201

Chain	Residue
B	GLU17
B	GLU50
B	HIS53
B	FE202
B	HOH317
B	HOH319

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE B 202

Chain	Residue
B	GLU50
B	GLU94
B	GLU130
B	FE201
B	HOH319

site_id	BC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 203

Chain	Residue
B	HIS93
B	LEU96
B	HOH303

site_id	BC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 204

Chain	Residue
B	GLU49
B	ASP162
B	HOH312

site_id	CC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL B 206

Chain	Residue
B	GLU8
B	HOH328
B	HOH329

site_id	CC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 207

Chain	Residue
B	GLN99
B	GLU103
B	CL208
F	HOH326

site_id	CC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL B 208

Chain	Residue
B	GLU103
B	CL207

site_id	CC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE C 201

Chain	Residue
C	GLU17
C	GLU50
C	HIS53
C	FE202
C	HOH301
C	HOH319

site_id	CC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE C 202

Chain	Residue
C	GLU50
C	GLU94
C	GLU130
C	FE201
C	HOH301

site_id	CC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 C 203

Chain	Residue
C	GLU89
C	HIS93
C	LEU96

site_id	CC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 C 204

Chain	Residue
C	GLU8
C	LEU67

site_id	CC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE HG C 205

Chain	Residue
A	CL209
A	CL210

site_id	CC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL C 207

Chain	Residue
C	GLU49
C	ASP162
C	HOH326

site_id	DC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE D 201

Chain	Residue
D	GLU17
D	GLU50
D	HIS53
D	FE202
D	HOH305
D	HOH323

site_id	DC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE D 202

Chain	Residue
D	GLU50
D	GLU94
D	GLU130
D	FE201
D	HOH305

site_id	DC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 D 203

Chain	Residue
D	GLN112
F	GLU74

site_id	DC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 204

Chain	Residue
D	ILE7
D	GLU8
D	LEU67

site_id	DC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 205

Chain	Residue
D	HIS93
D	LEU96
D	HOH318

site_id	DC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE HG D 206

Chain	Residue
D	CL208
D	CL209

site_id	DC7
Number of Residues	10
Details	BINDING SITE FOR RESIDUE MG D 207

Chain	Residue
D	GLU79
D	GLU79
D	GLU85
D	GLU85
D	HOH301
D	HOH301
D	HOH302
D	HOH302
D	HOH303
D	HOH303

site_id	DC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL D 208

Chain	Residue
D	HG206

site_id	DC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL D 209

Chain	Residue
D	HG206

site_id	EC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL D 210

Chain	Residue
D	THR72

site_id	EC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL D 212

Chain	Residue
D	HOH334

site_id	EC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL D 213

Chain	Residue
D	GLU79

site_id	EC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL D 214

Chain	Residue
D	HOH304
D	HOH335

site_id	EC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL D 215

Chain	Residue
D	HOH330

site_id	EC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE E 201

Chain	Residue
E	GLU17
E	GLU50
E	HIS53
E	FE202
E	HOH318
E	HOH319

site_id	EC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE E 202

Chain	Residue
E	GLU50
E	GLU94
E	GLU130
E	FE201
E	HOH319

site_id	EC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 E 203

Chain	Residue
E	HIS93
E	HOH308
E	HOH321

site_id	EC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 E 204

Chain	Residue
E	GLU79
E	TYR80
E	GLU85

site_id	FC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 E 205

Chain	Residue
E	ILE7
E	LEU67

site_id	FC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 E 206

Chain	Residue
E	GLU149
E	GLU149
E	GLU149
E	GLU149

site_id	FC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 E 207

Chain	Residue
E	ALA78
E	GLU89

site_id	FC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL E 208

Chain	Residue
E	ASN102

site_id	FC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL E 209

Chain	Residue
E	ASP162

site_id	FC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE F 201

Chain	Residue
F	GLU17
F	GLU50
F	HIS53
F	FE202
F	HOH316
F	HOH317

site_id	FC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE F 202

Chain	Residue
F	GLU50
F	GLU94
F	GLU130
F	FE201
F	HOH317

site_id	FC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 F 203

Chain	Residue
F	HIS93
F	HOH325
F	HOH326

site_id	FC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 F 204

Chain	Residue
F	ILE7
F	GLU8
F	ARG69

site_id	GC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL F 205

Chain	Residue
F	GLU49
F	ASP162

site_id	GC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL F 206

Chain	Residue
F	HIS34

site_id	GC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL F 207

Chain	Residue
F	GLU103
F	HOH332
F	HOH333

site_id	GC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL F 208

Chain	Residue
F	ASN102

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