4RD4
Structure of aIF2 gamma from sulfolobus solfataricus bound to gdpnp
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000049 | molecular_function | tRNA binding |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0001514 | biological_process | selenocysteine incorporation |
| A | 0001731 | biological_process | formation of translation preinitiation complex |
| A | 0003743 | molecular_function | translation initiation factor activity |
| A | 0003746 | molecular_function | translation elongation factor activity |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006412 | biological_process | translation |
| A | 0006413 | biological_process | translational initiation |
| A | 0006414 | biological_process | translational elongation |
| A | 0016259 | biological_process | selenocysteine metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0035368 | molecular_function | selenocysteine insertion sequence binding |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE GNP A 501 |
| Chain | Residue |
| A | VAL18 |
| A | GLY96 |
| A | ASN149 |
| A | LYS150 |
| A | ASP152 |
| A | SER184 |
| A | ALA185 |
| A | LEU186 |
| A | MG502 |
| A | HOH605 |
| A | HOH608 |
| A | ASP19 |
| A | HOH614 |
| A | HOH640 |
| A | HOH656 |
| A | HOH664 |
| A | HOH690 |
| A | HOH710 |
| A | HOH752 |
| A | HOH859 |
| A | HOH985 |
| A | HIS20 |
| A | GLY21 |
| A | LYS22 |
| A | THR23 |
| A | THR24 |
| A | MET45 |
| A | THR46 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 502 |
| Chain | Residue |
| A | THR23 |
| A | THR46 |
| A | GNP501 |
| A | HOH608 |
| A | HOH985 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE GNP A 503 |
| Chain | Residue |
| A | VAL223 |
| A | LYS225 |
| A | LYS234 |
| A | SER278 |
| A | ARG280 |
| A | GLY282 |
| A | ALA296 |
| A | GLY298 |
| A | HOH837 |
| A | HOH868 |
| A | HOH890 |
| A | HOH897 |
| A | HOH928 |
| A | HOH996 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE MPD A 504 |
| Chain | Residue |
| A | TYR300 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00119, ECO:0000269|PubMed:25690901, ECO:0007744|PDB:4RD1 |
| Chain | Residue | Details |
| A | ASP19 | |
| A | GLY44 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00119, ECO:0000269|PubMed:16407071, ECO:0000269|PubMed:25690901, ECO:0007744|PDB:2AHO |
| Chain | Residue | Details |
| A | THR23 | |
| A | THR46 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q8U082, ECO:0000255|HAMAP-Rule:MF_00119 |
| Chain | Residue | Details |
| A | CYS59 | |
| A | CYS62 | |
| A | CYS74 | |
| A | CYS77 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00119, ECO:0000269|PubMed:25690901, ECO:0007744|PDB:4RCY, ECO:0007744|PDB:4RD1 |
| Chain | Residue | Details |
| A | ASN149 | |
| A | SER184 |
