4RBM

Porphyromonas gingivalis gingipain K (Kgp) catalytic and immunoglobulin superfamily-like domains

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006508	biological_process	proteolysis
A	0008233	molecular_function	peptidase activity
A	0008234	molecular_function	cysteine-type peptidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 701

Chain	Residue
A	ASP313
A	PHE482
A	GLU491
A	HOH816
A	HOH850
A	HOH853

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 702

Chain	Residue
A	GLU343
A	HOH836
A	HOH874
A	ASP337
A	ASP339
A	PHE341

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA A 703

Chain	Residue
A	TYR402
A	VAL521
A	THR536
A	SER537
A	ASP542
A	HOH1275

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA A 704

Chain	Residue
A	ALA543
A	THR544
A	LEU546
A	SER549
A	TYR550
A	ASN551

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NI A 705

Chain	Residue
A	GLU355
A	GLU379
A	HIS707
A	ACT708

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA A 706

Chain	Residue
A	THR415
A	GLU498
A	HOH891
A	HOH904
A	HOH1060
A	HOH1204

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE HIS A 707

Chain	Residue
A	GLU355
A	GLU379
A	NI705
A	ACT708
A	HOH992

---

site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE ACT A 708

Chain	Residue
A	GLU355
A	GLU379
A	LYS497
A	NI705
A	HIS707
A	HOH1313
A	HOH1315

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACT A 709

Chain	Residue
A	GLU356
A	ARG495
A	HOH881
A	HOH1066
A	HOH1134

---

site_id	BC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE AZI A 710

Chain	Residue
A	HIS234
A	ASP339
A	TYR389
A	SER390
A	AZI712
A	HOH1221
A	HOH1251

---

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE AZI A 711

Chain	Residue
A	HIS234
A	GLY235
A	LEU237
A	TRP558
A	HOH1327

---

site_id	BC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE AZI A 712

Chain	Residue
A	ASP233
A	HIS234
A	ASP388
A	AZI710
A	HOH1001
A	HOH1221

---

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 713

Chain	Residue
A	LYS288
A	GLU320
A	TYR332
A	HOH1097

---

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 714

Chain	Residue
A	TYR418
A	ASN419
A	TYR420
A	GOL716

---

site_id	BC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 715

Chain	Residue
A	TYR420
A	LEU421
A	LYS422
A	PRO424
A	HOH1076
A	HOH1140

---

site_id	BC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 716

Chain	Residue
A	ASP416
A	VAL417
A	TYR418
A	LYS466
A	GOL714
A	HOH904
A	HOH1162
A	HOH1317

---

site_id	BC8
Number of Residues	14
Details	BINDING SITE FOR RESIDUE CKC A 717

Chain	Residue
A	SER511
A	TRP513
A	ASP516
A	HOH929
A	HOH1045
A	HOH1142
A	ASP229
A	THR232
A	THR442
A	ALA443
A	HIS444
A	GLY445
A	ASN475
A	CYS477

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000305|PubMed:25266723

Chain	Residue	Details
A	HIS444

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Nucleophile => ECO:0000269|PubMed:25266723

Chain	Residue	Details
A	CYS477

---

site_id	SWS_FT_FI3
Number of Residues	7
Details	BINDING: BINDING => ECO:0000269|PubMed:25266723, ECO:0007744|PDB:4RBM

Chain	Residue	Details
A	ASP313
A	ASP337
A	ASP339
A	PHE341
A	GLU343
A	PHE482
A	GLU491

---