4RAP

Crystal structure of bacterial iron-containing dodecameric glycosyltransferase TibC from enterotoxigenic E.coli H10407

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016740	molecular_function	transferase activity
A	0016757	molecular_function	glycosyltransferase activity
A	0046872	molecular_function	metal ion binding
B	0016740	molecular_function	transferase activity
B	0016757	molecular_function	glycosyltransferase activity
B	0046872	molecular_function	metal ion binding
C	0016740	molecular_function	transferase activity
C	0016757	molecular_function	glycosyltransferase activity
C	0046872	molecular_function	metal ion binding
D	0016740	molecular_function	transferase activity
D	0016757	molecular_function	glycosyltransferase activity
D	0046872	molecular_function	metal ion binding
E	0016740	molecular_function	transferase activity
E	0016757	molecular_function	glycosyltransferase activity
E	0046872	molecular_function	metal ion binding
F	0016740	molecular_function	transferase activity
F	0016757	molecular_function	glycosyltransferase activity
F	0046872	molecular_function	metal ion binding
G	0016740	molecular_function	transferase activity
G	0016757	molecular_function	glycosyltransferase activity
G	0046872	molecular_function	metal ion binding
H	0016740	molecular_function	transferase activity
H	0016757	molecular_function	glycosyltransferase activity
H	0046872	molecular_function	metal ion binding
I	0016740	molecular_function	transferase activity
I	0016757	molecular_function	glycosyltransferase activity
I	0046872	molecular_function	metal ion binding
J	0016740	molecular_function	transferase activity
J	0016757	molecular_function	glycosyltransferase activity
J	0046872	molecular_function	metal ion binding
K	0016740	molecular_function	transferase activity
K	0016757	molecular_function	glycosyltransferase activity
K	0046872	molecular_function	metal ion binding
L	0016740	molecular_function	transferase activity
L	0016757	molecular_function	glycosyltransferase activity
L	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE A 501

Chain	Residue
A	CYS339
A	CYS342
A	CYS358
A	CYS370

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE B 501

Chain	Residue
B	CYS339
B	CYS342
B	CYS358
B	CYS370

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE C 501

Chain	Residue
C	CYS342
C	CYS358
C	CYS370
C	CYS339

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO C 502

Chain	Residue
C	ARG189
C	ARG200
C	GLU201

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE D 501

Chain	Residue
D	CYS339
D	CYS342
D	CYS358
D	CYS370

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE E 1400

Chain	Residue
E	CYS339
E	CYS342
E	CYS358
E	CYS370

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE F 501

Chain	Residue
F	CYS339
F	CYS342
F	CYS358
F	CYS370

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE G 1400

Chain	Residue
G	CYS339
G	CYS342
G	CYS358
G	CYS370

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE H 501

Chain	Residue
H	CYS339
H	CYS342
H	CYS358
H	CYS370

---

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE I 501

Chain	Residue
I	CYS339
I	CYS342
I	CYS358
I	CYS370

---

site_id	BC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO I 502

Chain	Residue
I	ARG189
I	GLU201

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO I 503

Chain	Residue
F	TRP272
I	ALA259
I	HIS260
I	ASP276

---

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE J 501

Chain	Residue
J	CYS339
J	CYS342
J	CYS358
J	CYS370

---

site_id	BC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO J 502

Chain	Residue
J	ARG189
J	ARG200
J	GLU201

---

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE K 501

Chain	Residue
K	CYS339
K	CYS342
K	CYS358
K	CYS370

---

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE L 501

Chain	Residue
L	CYS339
L	CYS342
L	CYS358
L	CYS370

---

site_id	BC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO L 502

Chain	Residue
L	ARG189
L	GLU201

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"25310236","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	120
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25310236","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4RB4","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	36
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25310236","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4RAP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4RB4","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25310236","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4RAP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---