Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0016020 | cellular_component | membrane |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 3KU A 501 |
| Chain | Residue |
| A | ASP93 |
| A | ASP289 |
| A | GLY291 |
| A | THR292 |
| A | HOH972 |
| A | HOH993 |
| A | GLY95 |
| A | VAL130 |
| A | TYR132 |
| A | LYS168 |
| A | PHE169 |
| A | PHE170 |
| A | ILE171 |
| A | ARG189 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE TLA B 501 |
| Chain | Residue |
| B | ARG68 |
| B | ASN89 |
| B | HIS110 |
| B | ARG111 |
| B | ASN175 |
| B | HOH793 |
| B | HOH794 |
| B | HOH815 |
| B | HOH913 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE TLA B 502 |
| Chain | Residue |
| A | LYS300 |
| B | HIS106 |
| B | PHE108 |
| B | ASP167 |
| B | LYS168 |
| B | HOH738 |
| B | HOH834 |
| B | HOH927 |
| B | HOH994 |
| site_id | AC4 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE 3KU B 503 |
| Chain | Residue |
| B | ASP93 |
| B | GLY95 |
| B | VAL130 |
| B | TYR132 |
| B | LYS168 |
| B | PHE169 |
| B | PHE170 |
| B | ILE171 |
| B | ARG189 |
| B | ASP289 |
| B | GLY291 |
| B | THR292 |
| B | HOH996 |
| B | HOH998 |
| B | HOH999 |
| B | HOH1002 |
| B | HOH1006 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ILVDTGSSNFAV |
| Chain | Residue | Details |
| A | ILE90-VAL101 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP93 | |
| A | ASP289 | |
| B | ASP93 | |
| B | ASP289 | |
| Chain | Residue | Details |
| A | LYS126 | |
| B | LYS279 | |
| B | LYS285 | |
| B | LYS299 | |
| B | LYS300 | |
| B | LYS307 | |
| A | LYS275 | |
| A | LYS279 | |
| A | LYS285 | |
| A | LYS299 | |
| A | LYS300 | |
| A | LYS307 | |
| B | LYS126 | |
| B | LYS275 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN153 | |
| A | ASN172 | |
| A | ASN223 | |
| A | ASN354 | |
| B | ASN153 | |
| B | ASN172 | |
| B | ASN223 | |
| B | ASN354 | |
