4R8G

Crystal Structure of Myosin-1c tail in complex with Calmodulin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005102	molecular_function	signaling receptor binding
A	0005509	molecular_function	calcium ion binding
A	0030234	molecular_function	enzyme regulator activity
A	0046872	molecular_function	metal ion binding
B	0005102	molecular_function	signaling receptor binding
B	0005509	molecular_function	calcium ion binding
B	0030234	molecular_function	enzyme regulator activity
B	0046872	molecular_function	metal ion binding
E	0003774	molecular_function	cytoskeletal motor activity
E	0016459	cellular_component	myosin complex
H	0005102	molecular_function	signaling receptor binding
H	0005509	molecular_function	calcium ion binding
H	0030234	molecular_function	enzyme regulator activity
H	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 E 1101

Chain	Residue
E	ARG901
E	ARG903
E	GLU916

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 E 1102

Chain	Residue
E	LYS892
E	ARG903
E	LYS921

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 E 1103

Chain	Residue
E	HIS963
A	LYS94
E	ARG859
E	ARG865

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Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DKDGDGTITtkEL

Chain	Residue	Details
B	ASP20-LEU32
B	ASP56-PHE68
B	ASP93-LEU105
B	ASP129-PHE141

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	60
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448

Chain	Residue	Details
B	ASP20
B	GLU67
B	ASP93
B	ASP95
B	ASN97
B	TYR99
B	GLU104
B	ASP129
B	ASP131
B	ASP133
B	GLN135
B	ASP22
B	GLU140
A	ASP20
A	ASP22
A	ASP24
A	THR26
A	GLU31
A	ASP56
A	ASP58
A	ASN60
A	THR62
B	ASP24
A	GLU67
A	ASP93
A	ASP95
A	ASN97
A	TYR99
A	GLU104
A	ASP129
A	ASP131
A	ASP133
A	GLN135
B	THR26
A	GLU140
H	ASP20
H	ASP22
H	ASP24
H	THR26
H	GLU31
H	ASP56
H	ASP58
H	ASN60
H	THR62
B	GLU31
H	GLU67
H	ASP93
H	ASP95
H	ASN97
H	TYR99
H	GLU104
H	ASP129
H	ASP131
H	ASP133
H	GLN135
B	ASP56
H	GLU140
B	ASP58
B	ASN60
B	THR62

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site_id	SWS_FT_FI2
Number of Residues	3
Details	MOD_RES: N-acetylalanine => ECO:0000250|UniProtKB:P0DP23

Chain	Residue	Details
B	ALA1
A	ALA1
H	ALA1

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site_id	SWS_FT_FI3
Number of Residues	3
Details	MOD_RES: N6,N6,N6-trimethyllysine => ECO:0000250|UniProtKB:P0DP23

Chain	Residue	Details
B	LYS115
A	LYS115
H	LYS115

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