4R89

Crystal structure of paFAN1 - 5' flap DNA complex with Manganase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0003676	molecular_function	nucleic acid binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004527	molecular_function	exonuclease activity
A	0004528	molecular_function	phosphodiesterase I activity
A	0006281	biological_process	DNA repair
A	0006974	biological_process	DNA damage response
A	0008409	molecular_function	5'-3' exonuclease activity
A	0016787	molecular_function	hydrolase activity
A	0016788	molecular_function	hydrolase activity, acting on ester bonds
A	0017108	molecular_function	5'-flap endonuclease activity
A	0030145	molecular_function	manganese ion binding
A	0036297	biological_process	interstrand cross-link repair
A	0046872	molecular_function	metal ion binding
A	0070336	molecular_function	flap-structured DNA binding
E	0000287	molecular_function	magnesium ion binding
E	0003676	molecular_function	nucleic acid binding
E	0004518	molecular_function	nuclease activity
E	0004519	molecular_function	endonuclease activity
E	0004527	molecular_function	exonuclease activity
E	0004528	molecular_function	phosphodiesterase I activity
E	0006281	biological_process	DNA repair
E	0006974	biological_process	DNA damage response
E	0008409	molecular_function	5'-3' exonuclease activity
E	0016787	molecular_function	hydrolase activity
E	0016788	molecular_function	hydrolase activity, acting on ester bonds
E	0017108	molecular_function	5'-flap endonuclease activity
E	0030145	molecular_function	manganese ion binding
E	0036297	biological_process	interstrand cross-link repair
E	0046872	molecular_function	metal ion binding
E	0070336	molecular_function	flap-structured DNA binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN A 601

Chain	Residue
A	GLU368
A	ASP507
A	GLU522
A	VAL523
A	LYS524
B	DA5

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN A 602

Chain	Residue
B	DA5
A	GLU386
A	ASP507
B	DC4

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN E 601

Chain	Residue
E	GLU368
E	ASP507
E	GLU522
E	VAL523
E	LYS524
F	DA5

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN E 602

Chain	Residue
E	GLU386
E	ASP507
F	DC4
F	DA5

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25319828","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4R89","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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