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4R4I

Structure of RPA70N in complex with 5-(4-((6-(5-carboxyfuran-2-yl)-1-thioxo-3,4-dihydroisoquinolin-2(1H)-yl)methyl)phenyl)-1-(3,4-dichlorophenyl)-1H-pyrazole-3-carboxylic acid

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0005634cellular_componentnucleus
A0006260biological_processDNA replication
Functional Information from PDB Data
site_idAC1
Number of Residues14
DetailsBINDING SITE FOR RESIDUE 3HV A 201
ChainResidue
AARG31
ALEU87
AVAL93
AILE95
AHOH312
AHOH367
ATHR34
AARG41
AARG43
ASER55
AMET57
AALA59
ATHR60
AASN85

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: N-acetylmethionine => ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895
ChainResidueDetails
AMET1

site_idSWS_FT_FI2
Number of Residues3
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:26474068
ChainResidueDetails
ALYS22
ALYS88

227344

PDB entries from 2024-11-13

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