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4R37

Crystal structure analysis of LpxA, a UDP-N-acetylglucosamine acyltransferase from Bacteroides fragilis 9343 with UDP-GlcNAc

Functional Information from GO Data
ChainGOidnamespacecontents
A0008610biological_processlipid biosynthetic process
A0008780molecular_functionacyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
A0009245biological_processlipid A biosynthetic process
A0016746molecular_functionacyltransferase activity
A0046872molecular_functionmetal ion binding
B0008610biological_processlipid biosynthetic process
B0008780molecular_functionacyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
B0009245biological_processlipid A biosynthetic process
B0016746molecular_functionacyltransferase activity
B0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues17
DetailsBINDING SITE FOR RESIDUE UD1 A 1001
ChainResidue
AASP68
AGLY194
AARG197
AACT1004
AHOH1140
AHOH1169
AHOH1190
AHOH1216
AHOH1291
ALEU69
ALYS70
AHIS118
AILE145
AGLN154
AMET163
AASN191
AILE193

site_idAC2
Number of Residues13
DetailsBINDING SITE FOR RESIDUE PE5 A 1002
ChainResidue
AASN29
AGLU75
AGLY100
AARG101
AHOH1282
AHOH1286
AHOH1384
AHOH1386
AHOH1388
BALA231
BGLU232
BVAL233
BPRO234

site_idAC3
Number of Residues3
DetailsBINDING SITE FOR RESIDUE PG0 A 1003
ChainResidue
ALEU69
AASN107
AGLY125

site_idAC4
Number of Residues7
DetailsBINDING SITE FOR RESIDUE ACT A 1004
ChainResidue
AGLN67
AHIS115
AALA117
AASN130
AUD11001
AHOH1101
AHOH1346

site_idAC5
Number of Residues9
DetailsBINDING SITE FOR RESIDUE CA A 1005
ChainResidue
AASN89
AASN89
AASN89
AHOH1124
AHOH1124
AHOH1124
AHOH1229
AHOH1229
AHOH1229

site_idAC6
Number of Residues4
DetailsBINDING SITE FOR RESIDUE CA A 1006
ChainResidue
AHOH1212
AHOH1255
AHOH1321
BHOH538

site_idAC7
Number of Residues7
DetailsBINDING SITE FOR RESIDUE CA B 301
ChainResidue
AHOH1168
AHOH1188
AHOH1254
BHOH430
BHOH456
BHOH457
BHOH525

site_idAC8
Number of Residues6
DetailsBINDING SITE FOR RESIDUE ACT B 302
ChainResidue
BGLN67
BHIS115
BALA117
BASN130
BHOH403
BHOH577

site_idAC9
Number of Residues9
DetailsBINDING SITE FOR RESIDUE CA B 303
ChainResidue
BASN89
BASN89
BASN89
BHOH424
BHOH424
BHOH424
BHOH547
BHOH547
BHOH547

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PDB entries from 2024-10-30

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