4R1P

Crystal Structure of Thermophilic Geobacillus kaustophilus L-Arabinose isomerase with Mn2+

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005996	biological_process	monosaccharide metabolic process
A	0008733	molecular_function	L-arabinose isomerase activity
A	0016853	molecular_function	isomerase activity
A	0016861	molecular_function	intramolecular oxidoreductase activity, interconverting aldoses and ketoses
A	0019568	biological_process	arabinose catabolic process
A	0019569	biological_process	L-arabinose catabolic process to xylulose 5-phosphate
A	0030145	molecular_function	manganese ion binding
A	0046872	molecular_function	metal ion binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005996	biological_process	monosaccharide metabolic process
B	0008733	molecular_function	L-arabinose isomerase activity
B	0016853	molecular_function	isomerase activity
B	0016861	molecular_function	intramolecular oxidoreductase activity, interconverting aldoses and ketoses
B	0019568	biological_process	arabinose catabolic process
B	0019569	biological_process	L-arabinose catabolic process to xylulose 5-phosphate
B	0030145	molecular_function	manganese ion binding
B	0046872	molecular_function	metal ion binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005996	biological_process	monosaccharide metabolic process
C	0008733	molecular_function	L-arabinose isomerase activity
C	0016853	molecular_function	isomerase activity
C	0016861	molecular_function	intramolecular oxidoreductase activity, interconverting aldoses and ketoses
C	0019568	biological_process	arabinose catabolic process
C	0019569	biological_process	L-arabinose catabolic process to xylulose 5-phosphate
C	0030145	molecular_function	manganese ion binding
C	0046872	molecular_function	metal ion binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005996	biological_process	monosaccharide metabolic process
D	0008733	molecular_function	L-arabinose isomerase activity
D	0016853	molecular_function	isomerase activity
D	0016861	molecular_function	intramolecular oxidoreductase activity, interconverting aldoses and ketoses
D	0019568	biological_process	arabinose catabolic process
D	0019569	biological_process	L-arabinose catabolic process to xylulose 5-phosphate
D	0030145	molecular_function	manganese ion binding
D	0046872	molecular_function	metal ion binding
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005996	biological_process	monosaccharide metabolic process
E	0008733	molecular_function	L-arabinose isomerase activity
E	0016853	molecular_function	isomerase activity
E	0016861	molecular_function	intramolecular oxidoreductase activity, interconverting aldoses and ketoses
E	0019568	biological_process	arabinose catabolic process
E	0019569	biological_process	L-arabinose catabolic process to xylulose 5-phosphate
E	0030145	molecular_function	manganese ion binding
E	0046872	molecular_function	metal ion binding
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0005996	biological_process	monosaccharide metabolic process
F	0008733	molecular_function	L-arabinose isomerase activity
F	0016853	molecular_function	isomerase activity
F	0016861	molecular_function	intramolecular oxidoreductase activity, interconverting aldoses and ketoses
F	0019568	biological_process	arabinose catabolic process
F	0019569	biological_process	L-arabinose catabolic process to xylulose 5-phosphate
F	0030145	molecular_function	manganese ion binding
F	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN A 501

Chain	Residue
A	GLU307
A	GLU332
A	HIS349
A	HIS448
A	HOH768
A	HOH770

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN B 501

Chain	Residue
B	HIS448
B	HOH610
B	HOH714
B	GLU307
B	GLU332
B	HIS349

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN C 501

Chain	Residue
C	GLU307
C	GLU332
C	HIS349
C	HIS448
C	HOH610
C	HOH708

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN D 501

Chain	Residue
D	GLU307
D	GLU332
D	HIS349
D	HIS448
D	HOH796

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN E 501

Chain	Residue
E	GLU307
E	GLU332
E	HIS349
E	HIS448
E	HOH794

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN F 501

Chain	Residue
F	GLU307
F	GLU332
F	HIS349
F	HIS448
F	HOH624
F	HOH740

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00519

Chain	Residue	Details
A	GLU307
C	GLU332
C	HIS349
C	HIS448
D	GLU307
D	GLU332
D	HIS349
D	HIS448
E	GLU307
E	GLU332
E	HIS349
A	GLU332
E	HIS448
F	GLU307
F	GLU332
F	HIS349
F	HIS448
A	HIS349
A	HIS448
B	GLU307
B	GLU332
B	HIS349
B	HIS448
C	GLU307

---