4R14

Crystal structure of human CSN6 MPN domain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000338	biological_process	protein deneddylation
A	0008180	cellular_component	COP9 signalosome
A	0008233	molecular_function	peptidase activity
A	0008237	molecular_function	metallopeptidase activity
B	0000338	biological_process	protein deneddylation
B	0008180	cellular_component	COP9 signalosome
B	0008233	molecular_function	peptidase activity
B	0008237	molecular_function	metallopeptidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE HG A 301

Chain	Residue
A	CYS143
A	GLU147
A	PRO149

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE HG A 302

Chain	Residue
A	CYS143

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site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE HG A 303

Chain	Residue
A	HIS54
A	GLU88

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE HG A 304

Chain	Residue
A	PHE116
A	LEU119

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site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE HG B 301

Chain	Residue
B	GLU147
B	PRO149
B	CYS143

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site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE HG B 302

Chain	Residue
B	CYS143

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site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE HG B 303

Chain	Residue
B	HIS54

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site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE HG B 304

Chain	Residue
B	PHE116
B	LEU119

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	266
Details	Domain: {"description":"MPN","evidences":[{"source":"PROSITE-ProRule","id":"PRU01182","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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