Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005829 | cellular_component | cytosol |
| A | 0006979 | biological_process | response to oxidative stress |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019172 | molecular_function | glyoxalase III activity |
| A | 0019249 | biological_process | lactate biosynthetic process |
| A | 0061727 | biological_process | methylglyoxal catabolic process to lactate |
| A | 1903189 | biological_process | glyoxal metabolic process |
| A | 1990748 | biological_process | cellular detoxification |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005829 | cellular_component | cytosol |
| B | 0006979 | biological_process | response to oxidative stress |
| B | 0016829 | molecular_function | lyase activity |
| B | 0019172 | molecular_function | glyoxalase III activity |
| B | 0019249 | biological_process | lactate biosynthetic process |
| B | 0061727 | biological_process | methylglyoxal catabolic process to lactate |
| B | 1903189 | biological_process | glyoxal metabolic process |
| B | 1990748 | biological_process | cellular detoxification |
| C | 0005515 | molecular_function | protein binding |
| C | 0005634 | cellular_component | nucleus |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005739 | cellular_component | mitochondrion |
| C | 0005829 | cellular_component | cytosol |
| C | 0006979 | biological_process | response to oxidative stress |
| C | 0016829 | molecular_function | lyase activity |
| C | 0019172 | molecular_function | glyoxalase III activity |
| C | 0019249 | biological_process | lactate biosynthetic process |
| C | 0061727 | biological_process | methylglyoxal catabolic process to lactate |
| C | 1903189 | biological_process | glyoxal metabolic process |
| C | 1990748 | biological_process | cellular detoxification |
| D | 0005515 | molecular_function | protein binding |
| D | 0005634 | cellular_component | nucleus |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005739 | cellular_component | mitochondrion |
| D | 0005829 | cellular_component | cytosol |
| D | 0006979 | biological_process | response to oxidative stress |
| D | 0016829 | molecular_function | lyase activity |
| D | 0019172 | molecular_function | glyoxalase III activity |
| D | 0019249 | biological_process | lactate biosynthetic process |
| D | 0061727 | biological_process | methylglyoxal catabolic process to lactate |
| D | 1903189 | biological_process | glyoxal metabolic process |
| D | 1990748 | biological_process | cellular detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 201 |
| Chain | Residue |
| A | PHE17 |
| A | TRP21 |
| A | SER33 |
| A | MET52 |
| A | TYR53 |
| A | ASN55 |
| B | VAL50 |
| B | GLU51 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 202 |
| Chain | Residue |
| A | ALA64 |
| A | ASP65 |
| A | HOH356 |
| A | HOH390 |
| A | SER63 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO A 203 |
| Chain | Residue |
| A | SER47 |
| A | ARG48 |
| A | GLY79 |
| A | GLY80 |
| A | HOH308 |
| A | HOH474 |
| A | HOH475 |
| A | HOH509 |
| B | ARG26 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG B 201 |
| Chain | Residue |
| B | HOH428 |
| B | HOH489 |
| B | HOH490 |
| B | HOH491 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO C 201 |
| Chain | Residue |
| C | PHE17 |
| C | TRP21 |
| C | SER33 |
| C | MET52 |
| C | TYR53 |
| C | ASN55 |
| D | VAL50 |
| D | GLU51 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO C 202 |
| Chain | Residue |
| C | GLU14 |
| C | PHE17 |
| C | SER18 |
| C | MET46 |
| C | MET52 |
| C | HOH485 |
| D | SER18 |
| D | HOH352 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO C 203 |
| Chain | Residue |
| C | SER47 |
| C | ARG48 |
| C | GLY79 |
| C | GLY80 |
| C | HOH304 |
| C | HOH333 |
| C | HOH459 |
| C | HOH561 |
| D | ARG26 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG C 204 |
| Chain | Residue |
| C | HOH445 |
| C | HOH446 |
| C | HOH470 |
| C | HOH479 |
| D | HOH344 |
| D | HOH350 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG C 205 |
| Chain | Residue |
| A | HOH457 |
| C | HOH301 |
| C | HOH503 |
| C | HOH504 |
| C | HOH505 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG C 206 |
| Chain | Residue |
| B | HOH475 |
| C | HOH430 |
| C | HOH487 |
| C | HOH517 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO D 201 |
| Chain | Residue |
| C | VAL50 |
| C | GLU51 |
| D | PHE17 |
| D | TRP21 |
| D | SER33 |
| D | TYR53 |
| D | ASN55 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO D 202 |
| Chain | Residue |
| C | GLY135 |
| C | GLU139 |
| C | HOH343 |
| D | CSD111 |
| D | ALA112 |
| D | SER132 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG D 203 |
| Chain | Residue |
| B | GLU139 |
| B | HOH339 |
| B | HOH397 |
| B | HOH398 |
| D | GLY141 |
| D | HOH449 |
| D | HOH450 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"24758716","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
