4QTP
Crystal Structure of an Anti-sigma Factor Antagonist from Mycobacterium paratuberculosis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0043856 | molecular_function | anti-sigma factor antagonist activity |
| A | 0045893 | biological_process | positive regulation of DNA-templated transcription |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0043856 | molecular_function | anti-sigma factor antagonist activity |
| B | 0045893 | biological_process | positive regulation of DNA-templated transcription |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0043856 | molecular_function | anti-sigma factor antagonist activity |
| C | 0045893 | biological_process | positive regulation of DNA-templated transcription |
| D | 0006355 | biological_process | regulation of DNA-templated transcription |
| D | 0043856 | molecular_function | anti-sigma factor antagonist activity |
| D | 0045893 | biological_process | positive regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE CIT A 201 |
| Chain | Residue |
| A | GLY86 |
| A | PRO87 |
| A | ARG90 |
| A | ARG91 |
| A | HIS94 |
| A | HOH353 |
| D | ALA3 |
| D | EDO203 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 202 |
| Chain | Residue |
| A | ALA3 |
| A | SER6 |
| A | THR8 |
| A | SER23 |
| A | GLY24 |
| C | ALA33 |
| C | EDO202 |
| A | SER2 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 203 |
| Chain | Residue |
| A | SER2 |
| A | GLU57 |
| D | ARG91 |
| D | HIS94 |
| D | GOL204 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 204 |
| Chain | Residue |
| A | LYS65 |
| A | ALA69 |
| A | GOL205 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 205 |
| Chain | Residue |
| A | SER61 |
| A | LYS65 |
| A | EDO204 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE CIT B 201 |
| Chain | Residue |
| B | GLY86 |
| B | PRO87 |
| B | ARG90 |
| B | ARG91 |
| B | HIS94 |
| B | HOH325 |
| B | HOH382 |
| C | ALA3 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 202 |
| Chain | Residue |
| B | SER2 |
| B | ALA3 |
| B | SER6 |
| B | THR8 |
| B | SER23 |
| B | GLY24 |
| D | ALA33 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 203 |
| Chain | Residue |
| B | ASP99 |
| B | LYS100 |
| B | THR101 |
| B | PHE102 |
| B | HOH378 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 204 |
| Chain | Residue |
| B | SER61 |
| B | LYS65 |
| B | HOH398 |
| site_id | BC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE CIT C 201 |
| Chain | Residue |
| B | LEU59 |
| B | GLY60 |
| B | SER61 |
| B | PRO92 |
| B | LEU95 |
| B | THR96 |
| B | HOH331 |
| C | ASP27 |
| C | MET28 |
| C | PHE58 |
| C | GLY60 |
| C | SER61 |
| C | VAL62 |
| C | HOH302 |
| C | HOH340 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO C 202 |
| Chain | Residue |
| A | SER2 |
| A | EDO202 |
| C | GLN36 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 203 |
| Chain | Residue |
| B | PRO87 |
| C | PRO4 |
| C | GLU25 |
| C | GLU57 |
| C | HOH355 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 204 |
| Chain | Residue |
| C | ASP99 |
| C | LYS100 |
| C | PHE102 |
| C | PRO103 |
| site_id | BC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO C 205 |
| Chain | Residue |
| C | HIS14 |
| site_id | BC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO C 206 |
| Chain | Residue |
| C | ALA69 |
| C | THR70 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO C 207 |
| Chain | Residue |
| C | LEU104 |
| C | TYR105 |
| C | HOH365 |
| site_id | BC8 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE CIT D 201 |
| Chain | Residue |
| A | LEU59 |
| A | GLY60 |
| A | SER61 |
| A | PRO92 |
| A | LEU95 |
| A | THR96 |
| A | HOH335 |
| D | ASP27 |
| D | MET28 |
| D | PHE58 |
| D | GLY60 |
| D | SER61 |
| D | VAL62 |
| D | HOH301 |
| D | HOH337 |
| site_id | BC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO D 202 |
| Chain | Residue |
| D | LYS73 |
| D | HOH395 |
| D | THR70 |
| site_id | CC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO D 203 |
| Chain | Residue |
| A | PRO87 |
| A | CIT201 |
| D | GLU25 |
| D | HOH327 |
| site_id | CC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL D 204 |
| Chain | Residue |
| A | EDO203 |
| D | ARG85 |
| D | GLY86 |
| D | PRO87 |
| D | ARG90 |
| D | ARG91 |
