4QSV

Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with thymidine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006325	biological_process	chromatin organization
A	0006355	biological_process	regulation of transcription, DNA-templated
A	0016887	molecular_function	ATP hydrolysis activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 A 1201

Chain	Residue
A	ARG987
A	ARG990
A	ARG994
A	HIS1041
A	ARG1067
A	ARG1072
A	HOH1429
A	HOH1431

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 1202

Chain	Residue
A	PHE986
A	ARG990
A	LEU1044
A	HOH1318
A	HOH1350
A	HOH1482
A	GLU983

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 1203

Chain	Residue
A	GLU988
A	GLU1092
A	LEU1093
A	ASP1094
A	HOH1441
A	HOH1442

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 1204

Chain	Residue
A	LYS1047
A	ARG1051
A	ASP1054
A	TYR1086
A	HOH1472

---

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO A 1205

Chain	Residue
A	HIS998
A	GLU1091
A	GLU1092
A	LEU1093
A	ASP1094
A	HOH1442
A	HOH1446
A	HOH1475

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1206

Chain	Residue
A	LYS1047
A	GLU1098
A	HOH1315
A	HOH1472

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1207

Chain	Residue
A	LYS1037
A	LYS1042
A	HOH1445
A	HOH1498

---

site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 1208

Chain	Residue
A	ARG1082
A	ASP1083
A	TYR1086
A	HOH1301
A	HOH1393
A	HOH1458
A	HOH1479

---

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 1209

Chain	Residue
A	GLN1099
A	GLU1102
A	GLU1106

---

site_id	BC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE THM A 1210

Chain	Residue
A	VAL1008
A	VAL1013
A	GLU1017
A	VAL1018
A	TYR1063
A	ASN1064
A	ILE1074
A	HOH1351
A	HOH1374
A	HOH1460

---