4QSS

Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with N-Methyl-2-pyrrolidone (NMP)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006325	biological_process	chromatin organization
A	0006355	biological_process	regulation of transcription, DNA-templated
A	0016887	molecular_function	ATP hydrolysis activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 1201

Chain	Residue
A	ARG987
A	ARG990
A	ARG994
A	ARG1067
A	ARG1072
A	HOH1377

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site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 A 1202

Chain	Residue
A	MPD1204
A	HOH1375
A	HOH1375
A	HOH1376
A	HOH1376
A	LYS1042
A	LYS1042
A	MPD1204

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MPD A 1203

Chain	Residue
A	HIS998
A	GLU1092
A	MPD1205
A	HOH1351

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site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MPD A 1204

Chain	Residue
A	LYS1026
A	SER1036
A	SO41202
A	SO41202
A	HOH1338
A	HOH1375
A	HOH1462

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site_id	AC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MPD A 1205

Chain	Residue
A	GLU988
A	PHE992
A	PRO1069
A	GLU1092
A	LEU1093
A	ASP1094
A	PHE1097
A	MPD1203
A	HOH1305

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site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL A 1206

Chain	Residue
A	ILE1089
A	LEU1093

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site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MB3 A 1207

Chain	Residue
A	VAL1008
A	ASN1064
A	ILE1074
A	HOH1312

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