4QSH

Crystal Structure of L. monocytogenes Pyruvate Carboxylase in complex with Cyclic-di-AMP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004736	molecular_function	pyruvate carboxylase activity
A	0005524	molecular_function	ATP binding
A	0006090	biological_process	pyruvate metabolic process
A	0006094	biological_process	gluconeogenesis
A	0046872	molecular_function	metal ion binding
B	0003824	molecular_function	catalytic activity
B	0004736	molecular_function	pyruvate carboxylase activity
B	0005524	molecular_function	ATP binding
B	0006090	biological_process	pyruvate metabolic process
B	0006094	biological_process	gluconeogenesis
B	0046872	molecular_function	metal ion binding
C	0003824	molecular_function	catalytic activity
C	0004736	molecular_function	pyruvate carboxylase activity
C	0005524	molecular_function	ATP binding
C	0006090	biological_process	pyruvate metabolic process
C	0006094	biological_process	gluconeogenesis
C	0046872	molecular_function	metal ion binding
D	0003824	molecular_function	catalytic activity
D	0004736	molecular_function	pyruvate carboxylase activity
D	0005524	molecular_function	ATP binding
D	0006090	biological_process	pyruvate metabolic process
D	0006094	biological_process	gluconeogenesis
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FLC A 2001

Chain	Residue
A	ARG420
A	GLY466
A	ASN1047
A	GLN1049
A	ARG1051

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN A 2002

Chain	Residue
A	ASP541
A	LYS710
A	HIS739
A	HIS741

---

site_id	AC3
Number of Residues	13
Details	BINDING SITE FOR RESIDUE 2BA A 2003

Chain	Residue
A	TYR722
A	TYR749
A	ALA753
A	SER756
A	2BA2004
A	HOH2112
A	HOH2118
A	HOH2147
A	HOH2152
D	TYR722
D	TYR749
D	ALA753
D	SER756

---

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE 2BA A 2004

Chain	Residue
A	2BA2003
C	2BA1201

---

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FLC B 2001

Chain	Residue
B	ARG420
B	ARG422
B	GLY466
B	LEU1046
B	ASN1047
B	GLN1049
B	ARG1051

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN B 2002

Chain	Residue
B	ASP541
B	LYS710
B	HIS739
B	HIS741

---

site_id	AC7
Number of Residues	13
Details	BINDING SITE FOR RESIDUE 2BA C 1201

Chain	Residue
A	2BA2004
B	TYR722
B	TYR749
B	ALA753
B	SER756
C	TYR722
C	TYR749
C	ALA753
C	SER756
C	HOH1322
C	HOH1323
C	HOH1343
C	HOH1344

---

site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FLC C 1202

Chain	Residue
C	ARG420
C	ARG422
C	GLY466
C	LEU1046
C	ASN1047
C	GLN1049
C	ARG1051

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN C 1203

Chain	Residue
C	ASP541
C	LYS710
C	HIS739
C	HIS741

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FLC D 2001

Chain	Residue
D	ARG420
D	GLY466
D	LEU1046
D	ASN1047
D	GLN1049
D	ARG1051

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN D 2002

Chain	Residue
D	ASP541
D	LYS710
D	HIS739
D	HIS741

---

Functional Information from PROSITE/UniProt

site_id	PS00866
Number of Residues	15
Details	CPSASE_1 Carbamoyl-phosphate synthase subdomain signature 1. YPLMIKASlggGGrG

Chain	Residue	Details
A	TYR156-GLY170

---

site_id	PS00867
Number of Residues	8
Details	CPSASE_2 Carbamoyl-phosphate synthase subdomain signature 2. FIEVNPRV

Chain	Residue	Details
A	PHE288-VAL295

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