4QRI
2.35 Angstrom resolution crystal structure of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004422 | molecular_function | hypoxanthine phosphoribosyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006166 | biological_process | purine ribonucleoside salvage |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0032264 | biological_process | IMP salvage |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0052657 | molecular_function | guanine phosphoribosyltransferase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004422 | molecular_function | hypoxanthine phosphoribosyltransferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006166 | biological_process | purine ribonucleoside salvage |
| B | 0016757 | molecular_function | glycosyltransferase activity |
| B | 0032264 | biological_process | IMP salvage |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0052657 | molecular_function | guanine phosphoribosyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 201 |
| Chain | Residue |
| A | GLN20 |
| A | LYS21 |
| A | SER24 |
| A | HOH306 |
| A | HOH361 |
| A | HOH362 |
| B | PEG205 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 202 |
| Chain | Residue |
| A | ARG166 |
| A | LYS45 |
| A | GLY46 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 203 |
| Chain | Residue |
| A | PHE60 |
| A | SER61 |
| A | LYS80 |
| B | ARG164 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 204 |
| Chain | Residue |
| A | LEU103 |
| A | ASP104 |
| A | THR105 |
| A | GLY106 |
| A | PHE107 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG A 205 |
| Chain | Residue |
| A | LYS45 |
| A | ARG70 |
| A | GLY163 |
| A | ARG166 |
| A | HOH344 |
| A | HOH360 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 201 |
| Chain | Residue |
| B | TYR111 |
| B | ARG114 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 202 |
| Chain | Residue |
| A | ARG164 |
| A | TYR165 |
| B | PHE60 |
| B | SER61 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 203 |
| Chain | Residue |
| B | LYS45 |
| B | GLY46 |
| B | ARG166 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 204 |
| Chain | Residue |
| B | LEU103 |
| B | ASP104 |
| B | THR105 |
| B | GLY106 |
| B | PHE107 |
| B | HOH346 |
| B | HOH371 |
| site_id | BC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PEG B 205 |
| Chain | Residue |
| A | ARG12 |
| A | PHE13 |
| A | ASP17 |
| A | TRP147 |
| A | SO4201 |
| A | HOH306 |
| B | GLU31 |
| B | ASP32 |
| B | LYS143 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG B 206 |
| Chain | Residue |
| B | ASP17 |
| B | GLU82 |
| B | TRP147 |
Functional Information from PROSITE/UniProt
| site_id | PS00103 |
| Number of Residues | 13 |
| Details | PUR_PYR_PR_TRANSFER Purine/pyrimidine phosphoribosyl transferases signature. VIIVEDILDTGfT |
| Chain | Residue | Details |
| A | VAL96-THR108 |
