4QQY

Crystal structure of T. fusca Cas3-ADP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003724	molecular_function	RNA helicase activity
A	0004386	molecular_function	helicase activity
A	0004518	molecular_function	nuclease activity
A	0005524	molecular_function	ATP binding
A	0005829	cellular_component	cytosol
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding
A	0051607	biological_process	defense response to virus
C	0000166	molecular_function	nucleotide binding
C	0003724	molecular_function	RNA helicase activity
C	0004386	molecular_function	helicase activity
C	0004518	molecular_function	nuclease activity
C	0005524	molecular_function	ATP binding
C	0005829	cellular_component	cytosol
C	0016787	molecular_function	hydrolase activity
C	0046872	molecular_function	metal ion binding
C	0051607	biological_process	defense response to virus
E	0000166	molecular_function	nucleotide binding
E	0003724	molecular_function	RNA helicase activity
E	0004386	molecular_function	helicase activity
E	0004518	molecular_function	nuclease activity
E	0005524	molecular_function	ATP binding
E	0005829	cellular_component	cytosol
E	0016787	molecular_function	hydrolase activity
E	0046872	molecular_function	metal ion binding
E	0051607	biological_process	defense response to virus
G	0000166	molecular_function	nucleotide binding
G	0003724	molecular_function	RNA helicase activity
G	0004386	molecular_function	helicase activity
G	0004518	molecular_function	nuclease activity
G	0005524	molecular_function	ATP binding
G	0005829	cellular_component	cytosol
G	0016787	molecular_function	hydrolase activity
G	0046872	molecular_function	metal ion binding
G	0051607	biological_process	defense response to virus

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE A 1001

Chain	Residue
A	ASP84
A	HIS115
A	HIS149
A	HIS150
A	FE1002
B	DA12

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE A 1002

Chain	Residue
A	ASP215
A	FE1001
B	DA12
A	HIS37
A	HIS83
A	ASP84

---

site_id	AC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE ADP A 1003

Chain	Residue
A	LEU277
A	LYS279
A	PRO280
A	ASN281
A	GLN284
A	MET307
A	GLY308
A	GLU309
A	GLY310
A	GLU313
A	ARG692

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE C 1001

Chain	Residue
C	ASP84
C	HIS115
C	HIS149
C	HIS150
C	FE1002
D	DA12

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE C 1002

Chain	Residue
C	HIS37
C	HIS83
C	ASP84
C	ASP215
C	FE1001
D	DA12

---

site_id	AC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE ADP C 1003

Chain	Residue
C	LEU277
C	LYS279
C	ASN281
C	GLN284
C	MET307
C	GLY308
C	GLU309
C	GLY310
C	GLU313
C	ARG692

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE E 1001

Chain	Residue
E	ASP84
E	HIS115
E	HIS149
E	HIS150
E	FE1002
F	DA12

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE E 1002

Chain	Residue
E	HIS37
E	HIS83
E	ASP84
E	ASP215
E	FE1001
F	DA12

---

site_id	AC9
Number of Residues	12
Details	BINDING SITE FOR RESIDUE ADP E 1003

Chain	Residue
E	LEU277
E	SER278
E	LYS279
E	PRO280
E	ASN281
E	GLN284
E	GLY308
E	GLY310
E	THR312
E	GLU313
E	ARG347
E	ARG692

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE G 1001

Chain	Residue
G	ASP84
G	HIS115
G	HIS149
G	HIS150
G	FE1002
H	DA12

---

site_id	BC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FE G 1002

Chain	Residue
G	HIS37
G	HIS83
G	ASP84
G	LYS87
G	ASP215
G	FE1001
H	DA12

---

site_id	BC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE ADP G 1003

Chain	Residue
G	LEU277
G	LYS279
G	ASN281
G	GLN284
G	MET307
G	GLY308
G	GLU309
G	GLY310
G	GLU313
G	ARG347
G	ARG692

---