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4QQ3

Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae, deletion mutant, in complex with XMP

Functional Information from GO Data
ChainGOidnamespacecontents
A0003824molecular_functioncatalytic activity
A0003938molecular_functionIMP dehydrogenase activity
A0006164biological_processpurine nucleotide biosynthetic process
A0016491molecular_functionoxidoreductase activity
Functional Information from PDB Data
site_idAC1
Number of Residues22
DetailsBINDING SITE FOR RESIDUE XMP A 501
ChainResidue
AALA49
AGLY341
AGLY342
AGLY363
ASER364
ATYR387
AGLY389
AMET390
AHOH610
AHOH613
AHOH617
AASN279
AHOH647
AHOH663
AHOH712
AGLY304
ASER305
AILE306
ACYS307
ATHR308
ATHR309
AASP340

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE CL A 502
ChainResidue
AVAL280
AALA281
ATHR282
AHOH634
AHOH723

site_idAC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE CL A 503
ChainResidue
ATHR12
AARG310
AGLN319
AHOH687

Functional Information from PROSITE/UniProt
site_idPS00487
Number of Residues13
DetailsIMP_DH_GMP_RED IMP dehydrogenase / GMP reductase signature. VKVGIGpGSICtT
ChainResidueDetails
AVAL297-THR309

226707

PDB entries from 2024-10-30

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