4QNN

Crystal Structure of phospholipase A 1 from hornet(Vespa basalis) venom

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0006629	biological_process	lipid metabolic process
A	0008970	molecular_function	glycerophospholipid phospholipase A1 activity
A	0016042	biological_process	lipid catabolic process
A	0016298	molecular_function	lipase activity
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0006629	biological_process	lipid metabolic process
B	0008970	molecular_function	glycerophospholipid phospholipase A1 activity
B	0016042	biological_process	lipid catabolic process
B	0016298	molecular_function	lipase activity
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0006629	biological_process	lipid metabolic process
C	0008970	molecular_function	glycerophospholipid phospholipase A1 activity
C	0016042	biological_process	lipid catabolic process
C	0016298	molecular_function	lipase activity
D	0005576	cellular_component	extracellular region
D	0005615	cellular_component	extracellular space
D	0006629	biological_process	lipid metabolic process
D	0008970	molecular_function	glycerophospholipid phospholipase A1 activity
D	0016042	biological_process	lipid catabolic process
D	0016298	molecular_function	lipase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 401

Chain	Residue
A	LYS241
A	HG406
B	CL402

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 402

Chain	Residue
A	LYS298
A	HOH577
B	CL402
B	CL407
B	HG413

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 403

Chain	Residue
A	LYS241
A	CL404
A	HOH513
C	HOH676
A	GLU238

---

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 404

Chain	Residue
A	CL403
C	HOH676

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE HG A 406

Chain	Residue
A	LYS241
A	CL401
A	HOH577
B	CL402

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 401

Chain	Residue
B	LYS241
B	HIS242
B	CL405
C	HOH682

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL B 402

Chain	Residue
A	CL401
A	CL402
A	HG406
A	HOH577
B	CL407
B	HG413

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 403

Chain	Residue
B	GLU238
B	LYS241
B	CL404
B	CL410

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 404

Chain	Residue
B	GLU238
B	LYS241
B	CL403
B	CL410

---

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 405

Chain	Residue
B	CL401
C	HOH643
C	HOH682
C	HOH694

---

site_id	BC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL B 406

Chain	Residue
B	CL409
C	HOH635

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 407

Chain	Residue
A	CL402
B	LYS72
B	CL402
B	HG413

---

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 408

Chain	Residue
B	CL411
C	CL502
D	HOH544
D	HOH545

---

site_id	BC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL B 409

Chain	Residue
B	CL406

---

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 410

Chain	Residue
B	LYS241
B	CL403
B	CL404
D	HOH543

---

site_id	BC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL B 411

Chain	Residue
B	CL408
C	CL502

---

site_id	BC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL B 412

Chain	Residue
B	LYS298
C	HOH682
C	HOH694

---

site_id	BC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE HG B 413

Chain	Residue
A	CL402
B	GLU243
B	ASN272
B	CL402
B	CL407

---

site_id	CC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL C 501

Chain	Residue
C	LYS298
C	CL502
C	CL504
C	HG505

---

site_id	CC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL C 502

Chain	Residue
B	CL408
B	CL411
C	CL501
C	CL504
C	HG505

---

site_id	CC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL C 503

Chain	Residue
C	GLU238

---

site_id	CC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL C 504

Chain	Residue
C	CL501
C	CL502
C	HG505

---

site_id	CC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE HG C 505

Chain	Residue
C	HIS242
C	CL501
C	CL502
C	CL504

---

site_id	CC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL D 401

Chain	Residue
C	HOH650

---

site_id	CC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL D 402

Chain	Residue
D	CL403

---

site_id	CC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL D 403

Chain	Residue
D	GLU238
D	CL402
D	HOH592
D	HOH597

---

Functional Information from PROSITE/UniProt

site_id	PS00107
Number of Residues	30
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGLGKYSEIIgLdpagpsfksndcse....RICK

Chain	Residue	Details
A	LEU153-LYS182

---

site_id	PS00120
Number of Residues	10
Details	LIPASE_SER Lipases, serine active site. IRLIGHSLGA

Chain	Residue	Details
A	ILE131-ALA140

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"description":"Nucleophile"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Active site: {"description":"Charge relay system","evidences":[{"source":"PROSITE-ProRule","id":"PRU10037","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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