4QN0

Crystal structure of the CPS-6 mutant Q130K

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding
B	0003676	molecular_function	nucleic acid binding
B	0016787	molecular_function	hydrolase activity
B	0046872	molecular_function	metal ion binding
C	0003676	molecular_function	nucleic acid binding
C	0016787	molecular_function	hydrolase activity
C	0046872	molecular_function	metal ion binding
D	0003676	molecular_function	nucleic acid binding
D	0016787	molecular_function	hydrolase activity
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 401

Chain	Residue
A	HIS148
A	ASN180
A	HOH532
A	HOH541
A	HOH542
A	HOH546

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG B 401

Chain	Residue
B	HOH559
B	HOH560
B	ASN180
B	HOH540
B	HOH555

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 401

Chain	Residue
C	ASN180
C	HOH535
C	HOH536
C	HOH539
C	HOH541

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site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG D 401

Chain	Residue
D	ASN180
D	HOH523
D	HOH524
D	HOH525
D	HOH530

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Functional Information from PROSITE/UniProt

site_id	PS01070
Number of Residues	9
Details	NUCLEASE_NON_SPEC DNA/RNA non-specific endonucleases active site. DRGHLaaaG

Chain	Residue	Details
A	ASP145-GLY153

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU10047

Chain	Residue	Details
A	HIS148
B	HIS148
C	HIS148
D	HIS148

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	ASN180
B	ASN180
C	ASN180
D	ASN180

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