4QMQ

MST3 in complex with CP-673451

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004672	molecular_function	protein kinase activity
A	0005524	molecular_function	ATP binding
A	0006468	biological_process	protein phosphorylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	BINDING SITE FOR RESIDUE 34U A 401

Chain	Residue
A	ILE30
A	ASP109
A	ALA148
A	ASN149
A	LEU151
A	ASP162
A	TYR291
A	HOH503
A	HOH520
A	HOH603
A	GLY33
A	ALA51
A	GLU70
A	MET99
A	GLU100
A	TYR101
A	LEU102
A	GLY105

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 402

Chain	Residue
A	LYS245
A	LYS272
A	ARG276

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PEG A 403

Chain	Residue
A	ASP43
A	TYR86
A	TYR89
A	HOH530

---

Functional Information from PROSITE/UniProt

site_id	PS00107
Number of Residues	24
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGKGSFGEVFkGidnrtqkv..........VAIK

Chain	Residue	Details
A	ILE30-LYS53

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	14
Details	Motif: {"description":"Bipartite nuclear localization signal"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	13
Details	Binding site: {}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine; by autocatalysis","evidences":[{"source":"PubMed","id":"17046825","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19604147","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20124694","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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